GABA Modulators
GABA modulators are compounds that influence the function of GABA (gamma-aminobutyric acid) receptors, the primary inhibitory neurotransmitter receptors in the central nervous system. These modulators can either enhance or inhibit GABAergic activity, affecting neuronal excitability and synaptic transmission. GABA modulators are crucial in the treatment and study of various neurological and psychiatric disorders, including anxiety, epilepsy, and insomnia. At CymitQuimica, we offer a wide range of GABA modulators to support your research in neuroscience, pharmacology, and neurotherapeutics.
Products of "GABA Modulators"
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Fludiazepam
CAS:Controlled ProductApplications Fludiazepam is a drug which is a benzodiazepine derivative. Fludiazepam possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. References Fang, S.Y., et al.: Drug. Alcohol. Depend., 104, 140 (2009); Esteki, M., et al.: Chem. Biol. Drug. Design., 72, 409 (2008);Formula:C16H12ClFN2OColor and Shape:White To Off-WhiteMolecular weight:302.7307(R)-3-amino-9-fluoro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
Purity:97%Molecular weight:269.27899169921875Mexazolam
CAS:Controlled ProductApplications Mexazolam is a benzodiazepine derivative and have been investigated for its therapeutic value in treating anxiety. Mexazolam is known to be metabolized via the CYP3A4 pathway. References Ferreira, L., et al.: Clin. Drug. Investig., 23, 235 (2003); Ishigami, M., et al.: Drug. Metab. Dispos., 30, 904 (2002); Sheridan, R.P., et al.: J. Med. Chem., 50, 3173 (2007);Formula:C18H16Cl2N2O2Color and Shape:NeatMolecular weight:363.24Sodium Barbital
CAS:Controlled ProductFormula:C8H11N2O3·NaColor and Shape:NeatMolecular weight:206.17Alpidem
CAS:Controlled ProductApplications A peripheral benzodiazepine GABAA receptor ligand, a new anxiolytic. References Min, D., et al.: Pharmacotherapy, 12, 68 (1992), Rothwell, C., et al.: J. Toxicol. Sci., 27, 35 (2002), Gonzalez-Diaz, H., et al.: Bioorg. Med. Chem. Lett., 15, 1651 (2005), Boelsterli, U., et al.: Curr. Drug Metab., 7, 715 (2006), Rietjens, I., et al.: Chem. Res. Toxicol., 19, 977 (2006),Formula:C21H23Cl2N3OColor and Shape:NeatMolecular weight:404.337-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:162.23599243164062Methocarbamol-d3
CAS:Controlled ProductApplications Methocarbamol-d3is deuterium labelled methocarbamol (M225950), which is a muscle relaxant (skeletal). References Topliss, J., et al.: J. Med. Chem., 22, 1238 (1979), Walters, W., et al.: Drug Discov. Today., 3, 160 (1998), Baldi, P., et al.: Bioinformatics, 16, 412 (2000), Kouznetsov, V., et al.: J. Arch. Pharm., 337, 127 (2004),Formula:C11H12D3NO5Color and Shape:NeatMolecular weight:244.267-Acetamido Clonazepam
CAS:Controlled ProductApplications Clonazepam (C587080) metabolite. References Huang, W., et al.: J. Anal. Toxicol., 19, 333 (1995), Rittner, M., et al.: J. Anal. Toxicol., 25, 115 (2001),Formula:C17H14ClN3O2Color and Shape:NeatMolecular weight:327.76Meclonazepam
CAS:Controlled ProductApplications Meclonazepam, is a drug of a benzodiazepine class similar in structure to Clonazepam (C587080). It has sedative and anxiolytic properties. It has also shown to have anti-parasitic effects against the parasitic worm Schistosoma mansoni. References O Boyle C., et al.: Euro. J. Clinic. Pharmacol., 29 (1), 105 (1985); Ansseau, M., et al.: Psychopharmacology, 87 (2), 130 (1985);Formula:C16H12ClN3O3Color and Shape:Off White SolidMolecular weight:329.74
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