
GABA Modulators
GABA modulators are compounds that influence the function of GABA (gamma-aminobutyric acid) receptors, the primary inhibitory neurotransmitter receptors in the central nervous system. These modulators can either enhance or inhibit GABAergic activity, affecting neuronal excitability and synaptic transmission. GABA modulators are crucial in the treatment and study of various neurological and psychiatric disorders, including anxiety, epilepsy, and insomnia. At CymitQuimica, we offer a wide range of GABA modulators to support your research in neuroscience, pharmacology, and neurotherapeutics.
Products of "GABA Modulators"
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8-Demethyl-6-hydroxy Zolazepam
CAS:Controlled ProductApplications N-Demethylated-8-hydroxylated metabolite of the anesthetic agent, Zolazepam (Z613500). References Baukema, J. et al.: Res. Comm. Chem. Pathol. Pharmacol., 10, 227 (1975);Formula:C14H13FN4O2Color and Shape:NeatMolecular weight:288.283,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:176.1750030517578Midazolam-D4.maleate, 1mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C182H4H9ClFN3·C4H4O43-Hydroxy-prazepam-D5
CAS:Controlled ProductFormula:C19H12D5ClN2O2Color and Shape:NeatMolecular weight:345.84Bromazepam
CAS:Controlled ProductApplications Controlled substance (depressant). Anxiolytic. References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),Formula:C14H10BrN3OColor and Shape:WhiteMolecular weight:316.15Barbituric Acid
CAS:Impurity Fluorouracil EP Impurity A Applications Barbituric Acid (Fluorouracil EP Impurity A) is a parent compound of barbiturate drugs. Unsubstituted barbituric acid has no hypnotic properties. References Luo, Y., et al.: J. Med. Chem., 53, 3846 (2010), Tomasic, T., et al.: Eur. J. Med. Chem., 45, 1667 (2010), Gilbert, A., et al.: Bioorg. Med. Chem. Lett., 20, 636 (2010),Formula:C4H4N2O3Color and Shape:NeatMolecular weight:128.097-Amino Nitrazepam (1mg/ml in Methanol)
CAS:Controlled ProductFormula:C15H13N3OColor and Shape:Single SolutionMolecular weight:251.28Deschloro-Zopiclone
CAS:Controlled ProductApplications Deschloro-Zopiclone is a metabolite of Zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),Formula:C17H18N6O3Color and Shape:NeatMolecular weight:354.36Gabapentin 100 µg/mL in Acetonitrile:Methanol
CAS:Controlled ProductFormula:C9H17NO2Color and Shape:Single SolutionMolecular weight:171.24Pirenzepine dihydrochloride, 99%
CAS:A M1 muscarinic receptor antagonist This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C19H23Cl2N5O2Purity:99%Color and Shape:Crystals or powder or crystalline powder, White to pale yellowMolecular weight:424.331-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Formula:C10H10N2O2Purity:95%Color and Shape:SolidMolecular weight:190.1986Pentobarbital-d5
CAS:Controlled ProductApplications Pentobarbital-d5 is labelled Pentobarbital (P276000, sodium salt) which is a short-acting barbiturate. Typical applications for pentobarbital are sedative, hypnotic for short term, preanesthetic and control of convulsions in emergencies. References Schafer, E.W., et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Woster, P.S., et al.: Clin. Pharm., 9, 762 (1990), Evans, A.T., et al.: J. Am. Vet. Med. Assoc., 203, 664 (1993),Formula:C112H5H13N2O3Color and Shape:WhiteMolecular weight:231.301,3-Dimethylbarbituric acid
CAS:Formula:C6H8N2O3Purity:98%Color and Shape:SolidMolecular weight:156.1393Methyl N-[(2S)-4-Methyl-2-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]pentyl]carbamate
CAS:Color and Shape:Neat(Carbamoylamino)(diphenyl)acetic Acid
CAS:Controlled ProductFormula:C15H14N2O3Color and Shape:NeatMolecular weight:270.289-Nitro-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Purity:95.0%Molecular weight:207.188995361328125-(4-Methylphenyl)-5-phenylimidazolidine-2,4-dione
CAS:Controlled ProductFormula:C16H14N2O2Color and Shape:NeatMolecular weight:266.29SKF 81297C
CAS:Controlled ProductApplications SKF 81297C is a dopamine D1 agonist (1). References (1) Bergman, J., et. al.: J. Pharmacol. Exp. Ther., 273, 40 (1995)Formula:C16H17BrClNO2Color and Shape:NeatMolecular weight:370.67Lorazepam (100 μg/mL in Acetonitrile)
CAS:Controlled ProductFormula:C15H10Cl2N2O2Color and Shape:Single SolutionMolecular weight:321.16(Z)-2-Propylpent-3-enoic Acid
CAS:Controlled ProductFormula:C8H14O2Color and Shape:NeatMolecular weight:142.196Allylisopropylacetylurea
CAS:Controlled ProductApplications Allylisopropylacetylurea is used in a novel approach to cytochrome P-450 induction, through barbiturate-like activity. References Ruettinger, R. et al.: Biochim. Biophys. Acta Gen. Subj. et al.: 801, 374 (1984);Formula:C9H16N2O2Color and Shape:NeatMolecular weight:184.24Phenobarbital 1-Butyric Acid
CAS:Controlled ProductFormula:C16H18N2O5Color and Shape:NeatMolecular weight:318.32Triazolam N-Oxide
CAS:Controlled ProductApplications Triazolam N-Oxide is a derivative of Triazolam (T767380), a sedative. References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976); Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978); Pakes, G.E., et al.: Drugs, 22, 81 (1981)Formula:C17H12Cl2N4OColor and Shape:NeatMolecular weight:359.21