GABA Modulators
GABA modulators are compounds that influence the function of GABA (gamma-aminobutyric acid) receptors, the primary inhibitory neurotransmitter receptors in the central nervous system. These modulators can either enhance or inhibit GABAergic activity, affecting neuronal excitability and synaptic transmission. GABA modulators are crucial in the treatment and study of various neurological and psychiatric disorders, including anxiety, epilepsy, and insomnia. At CymitQuimica, we offer a wide range of GABA modulators to support your research in neuroscience, pharmacology, and neurotherapeutics.
Products of "GABA Modulators"
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Alpidem
CAS:Controlled ProductApplications A peripheral benzodiazepine GABAA receptor ligand, a new anxiolytic. References Min, D., et al.: Pharmacotherapy, 12, 68 (1992), Rothwell, C., et al.: J. Toxicol. Sci., 27, 35 (2002), Gonzalez-Diaz, H., et al.: Bioorg. Med. Chem. Lett., 15, 1651 (2005), Boelsterli, U., et al.: Curr. Drug Metab., 7, 715 (2006), Rietjens, I., et al.: Chem. Res. Toxicol., 19, 977 (2006),Formula:C21H23Cl2N3OColor and Shape:NeatMolecular weight:404.337-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:162.23599243164062Methocarbamol-d3
CAS:Controlled ProductApplications Methocarbamol-d3is deuterium labelled methocarbamol (M225950), which is a muscle relaxant (skeletal). References Topliss, J., et al.: J. Med. Chem., 22, 1238 (1979), Walters, W., et al.: Drug Discov. Today., 3, 160 (1998), Baldi, P., et al.: Bioinformatics, 16, 412 (2000), Kouznetsov, V., et al.: J. Arch. Pharm., 337, 127 (2004),Formula:C11H12D3NO5Color and Shape:NeatMolecular weight:244.267-Acetamido Clonazepam
CAS:Controlled ProductApplications Clonazepam (C587080) metabolite. References Huang, W., et al.: J. Anal. Toxicol., 19, 333 (1995), Rittner, M., et al.: J. Anal. Toxicol., 25, 115 (2001),Formula:C17H14ClN3O2Color and Shape:NeatMolecular weight:327.76Meclonazepam
CAS:Controlled ProductApplications Meclonazepam, is a drug of a benzodiazepine class similar in structure to Clonazepam (C587080). It has sedative and anxiolytic properties. It has also shown to have anti-parasitic effects against the parasitic worm Schistosoma mansoni. References O Boyle C., et al.: Euro. J. Clinic. Pharmacol., 29 (1), 105 (1985); Ansseau, M., et al.: Psychopharmacology, 87 (2), 130 (1985);Formula:C16H12ClN3O3Color and Shape:Off White SolidMolecular weight:329.74Bromazepam (1mg/mL in Methanol)
CAS:Controlled ProductFormula:C14H10BrN3OColor and Shape:ColourlessMolecular weight:316.155-Allyl-5-methallyl-barbituric Acid
CAS:Controlled ProductFormula:C11H14N2O3Color and Shape:NeatMolecular weight:222.247-AMINO-4-BOC-4,5-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE
CAS:Purity:97.0%Molecular weight:277.32400512695311'-Hydroxy Triazolam
CAS:Controlled ProductApplications A metabolite of Triazolam (T767380(M)), which is a sedative; a controlled substance (depressant). References Boxenbaum, H., et al.: J. Pharm. Pharm. Sci., 2, 47 (1999), Perloff, M., et al.: J. Pharmacol. Exp. Ther., 292, 618 (2000), Patki, K., et al.: Drug Metab. Dispos., 31, 938 (2003),Formula:C17H12Cl2N4OColor and Shape:Light GreenMolecular weight:359.21Zolpidem Hemitartrate
CAS:Controlled ProductFormula:C19H21N3O·C4H6O6Color and Shape:WhiteMolecular weight:764.87Cyclobenzaprine-d3 Hydrochloride
CAS:Controlled ProductApplications Use as muscle relaxant (skeletal). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Cotton, M.L., et al.: Anal. Profiles Drug Subs., 17, 41 (1988),Formula:C202H3H18N·ClHColor and Shape:White To YellowMolecular weight:314.87Phenobarbital N-Beta-D-Glucoside
CAS:Controlled ProductApplications A metabolite of Phenobarbital (P316760). References Soine, W.H., et al.: Drug Metab. Dispos., 12, 792 (1984), Soine, W.H., et al.: J. Pharmac. Sci., 80, 99 (1991),Formula:C18H22N2O8Color and Shape:NeatMolecular weight:394.38Methohexital (Mixture of Diastereomers)
CAS:Controlled ProductApplications Methohexital is a short-acting barbiturate used as a sedative. Methohexital is used an anesthetic for oral surgery and dentistry and is also used to induce anesthesia prior to electroconvulsive therapy (ECT). Methohexital is a Controlled Substance. Analog of secobarbital (S235000). References Avramov, M.N. et al.: Anesth. Analges., 81, 596 (1995); Hamid, S.K. et al.: Br. J. Anaesth., 77, 727 (1996);Formula:C14H18N2O3Color and Shape:NeatMolecular weight:262.30Butalbital (1.0 mg/mL in Methanol)
CAS:Controlled ProductFormula:C11H16N2O3Color and Shape:ColourlessMolecular weight:224.26Nordazepam-d5 (1.0 mg/mL in Methanol)
CAS:Controlled ProductFormula:C152H5H6ClN2OColor and Shape:Single SolutionMolecular weight:275.74Zopiclone
CAS:Controlled ProductStability Hygroscopic Applications Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic. References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),Formula:C17H17ClN6O3Color and Shape:White To Off-WhiteMolecular weight:388.81
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