GABA Modulators
GABA modulators are compounds that influence the function of GABA (gamma-aminobutyric acid) receptors, the primary inhibitory neurotransmitter receptors in the central nervous system. These modulators can either enhance or inhibit GABAergic activity, affecting neuronal excitability and synaptic transmission. GABA modulators are crucial in the treatment and study of various neurological and psychiatric disorders, including anxiety, epilepsy, and insomnia. At CymitQuimica, we offer a wide range of GABA modulators to support your research in neuroscience, pharmacology, and neurotherapeutics.
Products of "GABA Modulators"
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2-Hydroxypropyl 4-(2-Chlorophenyl)-6-nitro-quinazoline-2-carboxylate
Formula:C18H14ClN3O5Color and Shape:Neat5-Allyl-6-imino-5-(1-methyl-2-pentynyl)hydrouracil
CAS:Controlled ProductFormula:C13H17N3O2Color and Shape:NeatMolecular weight:460.6067-Fluoro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:194.1649932861328N-Desmethyl Clotiazepam
CAS:Controlled ProductApplications Clotiazepam (C587410) metabolite, with central nervous depressant and anxiolytic activity. References Ito, K. et al.: Biopharm. Drug. Dispos., 18, 293 (1997); Nakanishi, M. et al.: J. Med. Chem., 16, 214 (1973)Formula:C15H13ClN2OSColor and Shape:NeatMolecular weight:304.79Clotiazepam
CAS:Controlled ProductApplications A thienodiazepine derivative that possesses anxiolytic, skeletal muscle relaxant anticonvulsant, sedative properties as well as contributing to siginificant increase stage 2 NREM sleep. It binds to benzodiazepine site of the GABAA receptor where it acts as a full agonist resulting in enhanced GABA inhibitory effect at the GABAA receptor. Controlled Substance. References Mandrioli, R. et al.: Curr.Drug Metab., 8, 827 (2008); Nakazawa, Y. et al.: Psychopharmacol., 44, 165 (1975); Yakushiji, T. et al.: Br. J. Pharmacol., 98, 735 (1989);Formula:C16H15ClN2OSColor and Shape:Off-WhiteMolecular weight:318.82Methylphenobarbital
CAS:Controlled ProductApplications Controlled substance (depressant). Anticonvulsant; sedative; hypnotic. References Price, W.C., et al.: J. Pharm. Pharmacol., 6, 522 (1954), Brochman-Hanssen, E., et al.: J. Pharm. Sci., 58, 370 (1969), Lackner, H., et al.: Arch. Toxikol., 26, 220 (1970),Formula:C13H14N2O3Color and Shape:WhiteMolecular weight:246.264-(2-Methylpropyl)piperidine-2,6-dione (3-Isobutylglutarimide)
CAS:Controlled ProductFormula:C9H15NO2Color and Shape:NeatMolecular weight:169.224-Boc-7-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:266.3160095214844N-Methyl Zonisamide
CAS:Controlled ProductApplications A methylated analog of Zonisamide (Z700000) with anticonvulsant activity. References Uno, H., et al.: J. Med. Chem., 22, 180 (1979)Formula:C9H10N2O3SColor and Shape:NeatMolecular weight:226.25Tizanidine Hydrochloride
CAS:Controlled ProductApplications An α2-adrenergic agonist; centrally active myotonolytic. A muscle relaxant (skeletal). References Turski, L., et al.: Brain Res., 379, 367 (1986), Ono, H., et al.: Gen. Pharmacol., 17, 137 (1986), Hoogstraten, M.C., et al.: Acta Neurol. Scand., 77, 224 (1988)Formula:C9H8ClN5S·ClHColor and Shape:Light YellowMolecular weight:290.177-Bromo-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Purity:95+%Molecular weight:269.0979919433594Butobarbital-d5
CAS:Controlled ProductApplications Labelled Butobarbital, a barbiturate derivative that is used as a hypnotic agent with sedative and anticonvulsant properties. Butobarbital is a Controlled Substance. References Sitsen, J.M.A. et al.: Pharmac. Week., 109, 1 (1974); Adams, R.G.: Psychopharmacologia, 40, 185 (1974);Formula:C10H11D5N2O3Color and Shape:NeatMolecular weight:217.28N-Demethyl Olanzapine
CAS:Controlled ProductApplications A metabolite of Olanzapine.Formula:C16H18N4SColor and Shape:BrownMolecular weight:298.416-(8-Chloro-4,5-dihydro-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-ylidene)-2,4-cyclohexadien-1-one
CAS:Controlled ProductFormula:C18H14ClN3OColor and Shape:NeatMolecular weight:323.78Oxcarbazepine EP Impurity F
CAS:Controlled ProductFormula:C16H12ClNO2Color and Shape:NeatMolecular weight:286.00Nitrazepam (1.0 mg/mL in Acetonitrile)
CAS:Controlled ProductFormula:C15H11N3O3Color and Shape:ColourlessMolecular weight:281.274-Boc-8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:266.3160095214844
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