
GABA Modulators
GABA modulators are compounds that influence the function of GABA (gamma-aminobutyric acid) receptors, the primary inhibitory neurotransmitter receptors in the central nervous system. These modulators can either enhance or inhibit GABAergic activity, affecting neuronal excitability and synaptic transmission. GABA modulators are crucial in the treatment and study of various neurological and psychiatric disorders, including anxiety, epilepsy, and insomnia. At CymitQuimica, we offer a wide range of GABA modulators to support your research in neuroscience, pharmacology, and neurotherapeutics.
Products of "GABA Modulators"
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6-Chloro-1-methyl-4-phenyl-2(1H)-quinazolinone
CAS:Controlled ProductImpurity Diazepam EP Impurity E Applications 6-Chloro-1-methyl-4-phenyl-2(1H)-quinazolinone (Diazepam EP Impurity E) is an impurity of Temazepam (T017200), which is a pharmacologically active metabolite. It is used as a sedative and hypnotic drug. References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981)Formula:C15H11ClN2OColor and Shape:Light YellowMolecular weight:270.71Zaleplon
CAS:Controlled ProductApplications Selective non-benzodiazepine GABAA receptor agonist. References Allen, D., et al.: Eur. J. Clin. Pharmacol., 45, 313 (1993), Beer, B., et al.: J. Clin. Pharmacol., 34, 335 (1994), Rosen, A.S., et al.: Biopharm. Drug Dispos., 20, 171 (1999), Elie, R., et al.: J. Clin. Psychiatry, 60, 536 (1999), Heydorn, W.E., et al.: Expert Opin. Invest. Drugs, 9, 841 (2000)Formula:C17H15N5OColor and Shape:Off-WhiteMolecular weight:305.33Pentanoic Acid (Valeric Acid)
CAS:Controlled ProductFormula:C5H10O2Color and Shape:NeatMolecular weight:102.13Flunitrazepam
CAS:Controlled ProductApplications Flunitrazepam is used as an hypnotic. This is a controlled substance (depressant). References Sternbach, L.H., et al.: J. Med. Chem., 6, 261 (1963), Eidelberg, E., et al.: Neurology, 5, 223 (1965), Caplan, Y., et al.: J. Anal. Toxicol., 25, 396 (2001), Wood, M., et al.: Forensic Sci. Int., 150, 227 (2005),Formula:C16H12FN3O3Color and Shape:Off-WhiteMolecular weight:313.28(5RS)-5-Ethyl-2-imino-5-phenyldihydropyrimidine-4,6(1H,3H)-dione (2-Amino-5-ethyl-5-phenyl-4,6(1H,5H)-pyrimidinedione)
CAS:Controlled ProductFormula:C12H13N3O2Color and Shape:NeatMolecular weight:231.255-Phenyl-5-ethyl-2-thiobarbituric Acid
CAS:Controlled ProductFormula:C12H12N2O2SColor and Shape:NeatMolecular weight:248.3Phenobarbital (1.0mg/mL in Methanol)
CAS:Controlled ProductFormula:C12H12N2O3Color and Shape:Single SolutionMolecular weight:232.24Chlordiazepoxide-d5 (100ug/ml in Methanol)
CAS:Controlled ProductFormula:C162H5H9ClN3OColor and Shape:Single SolutionMolecular weight:304.792-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine
CAS:Controlled ProductApplications An Intermediate for the synthesis of Midazolam. References Walser, A., J. Org. Chem., 43, 936 (1978).Formula:C16H15ClFN3Color and Shape:NeatMolecular weight:303.76Alprazolam-d3
CAS:Controlled ProductApplications Controlled substance (depressant). Anxiolytic. References Sethy, V.H., et al.: Arch. Pharmacol., 301, 157 (1978), Fawcett, J.A., et al.: Pharmacotherapy, 2, 242 (1982),Formula:C17H10ClD3N4Color and Shape:NeatMolecular weight:311.807-Amino Nitrazepam
CAS:Controlled ProductApplications A metabolite of Nitrazepam (N490140). References Randall, L.O., et al.: Biochem. Pharmacol., 8, 15 (1961),Formula:C15H13N3OColor and Shape:Light YellowMolecular weight:251.284-Boc-9-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Purity:97.0%Molecular weight:262.35299682617197-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Formula:C10H9FN2O2Purity:97%Color and Shape:SolidMolecular weight:208.18917-Amino Nitrazepam-d5
CAS:Controlled ProductApplications A labelled metabolite of Nitrazepam (N490140(M)), which is an anticonvulsant; hypnotic.Controlled substance (depressant). References Randall, L.O., et al.: Biochem. Pharmacol., 8, 15 (1961), Rieder, et al.: Arzneim.-Forsch., 23, 212 (1973), Kangas, L., Acta Pharmacol. Toxicol., 45, 16 (1979), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 9, 487 (1980)Formula:C15H8D5N3OColor and Shape:Light Yellow SolidMolecular weight:256.31(2RS)-2-Ethyl-2-methylbutanedioic Acid
CAS:Controlled ProductFormula:C7H12O4Color and Shape:NeatMolecular weight:160.168Gabapentin-lactam 100 µg/mL in Acetonitrile
CAS:Formula:C9H15NOColor and Shape:Single SolutionMolecular weight:153.222,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPIN-8-YLAMINE 2HCL
CAS:Purity:97.0%Molecular weight:236.139999389648447-Amino-4-Boc-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Purity:97.0%Molecular weight:263.34100341796875Zolpidem
CAS:Controlled ProductApplications A selective non-benzodiazepine GABAA receptor agonist. Sedative, hypnotic. Controlled substance (depresssant). References Arbilla, S., et al.: Arch. Pharmacol., 330, 248 (1985), Cashman, J.N., et al.: Brit. J. Clin. Pharmacol., 21, 205 (1986)Formula:C19H21N3OColor and Shape:Off-WhiteMolecular weight:307.39