
Serotonin–Norepinephrine Reuptake Inhibitors (SNRI)
Serotonin–Norepinephrine Reuptake Inhibitors (SNRI) are a class of compounds that inhibit the reuptake of the neurotransmitters serotonin and norepinephrine, thereby increasing their levels in the synaptic cleft. This action enhances neurotransmission and is commonly used in the treatment of depression, anxiety, and chronic pain. SNRIs are vital tools in studying mood disorders and the development of antidepressant therapies. At CymitQuimica, we provide a selection of SNRIs to aid your research in psychopharmacology, mood disorders, and neurobiology.
Products of "Serotonin–Norepinephrine Reuptake Inhibitors (SNRI)"
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(R)-O-Desmethyl-Venlafaxine
CAS:Formula:C16H25NO2Color and Shape:White To Off-White SolidMolecular weight:263.38N-Desethyl L-Milnacipran HCl
Formula:C13H18N2O·HClColor and Shape:Off-White SolidMolecular weight:218.30 36.46Atomoxetine EP Impurity D HCl (Atomoxetine USP Related Compound B (R-Isomer))
CAS:Formula:C17H21NO·HClMolecular weight:255.36 36.46Venlafaxine EP Impurity A HCl (Descyclohexanol Venlafaxine HCl)
CAS:Formula:C11H17NO·HClColor and Shape:White To Off-White SolidMolecular weight:179.26 36.46Sibutramine USP Related Compound D-d7 (N-Desmethyl Sibutramine-d7 HCl)
CAS:Formula:C16H17D7ClN·HClColor and Shape:White To Off-White SolidMolecular weight:272.87 36.46Duloxetine EP Impurity A Maleate (Duloxetine USP Related Compound A Maleate)
CAS:Formula:C18H19NOS·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:297.42 116.07(2RS)-2-(Cyclohex-1-enyl)-2-(4-methoxyphenyl)-N,N-dimethylethanamine Hydrochloride
CAS:Controlled Product(2RS)-2-(Cyclohex-1-enyl)-2-(4-methoxyphenyl)-N,N-dimethylethanamine Hydrochloride is a white crystalline powder with a melting point of 136.5°C and a molecular formula of C13H20N2O. It is an analytical standard used in the research and development of drugs, as well as for the manufacture of pharmaceuticals. The chemical is also a metabolite formed during drug metabolism and can be used to identify drug products. (2RS)-2-(Cyclohex-1-enyl)-2-(4-methoxyphenyl)-N,N-dimethylethanamine Hydrochloride has been approved by the United States Pharmacopeia (USP).Formula:C17H25NO·ClHPurity:Min. 95%Molecular weight:295.85 g/molVenlafaxine Impurity 11
CAS:Formula:C17H25NO3Color and Shape:White To Off-White SolidMolecular weight:291.394-Hydroxy duloxetine glucuronide
Formula:C24H27NO8SColor and Shape:Pale Yellow SolidMolecular weight:489.55Atomoxetine EP Impurity B-d3 HCl ((S)-Atomoxetine-d3 HCl)
CAS:Formula:C17H18D3NO·HClMolecular weight:258.38 36.46Duloxetine HCl
CAS:Formula:C18H19NOS·HClColor and Shape:White To Off-White SolidMolecular weight:297.42 36.46L-Milnacipran Carbamoyl-β-D-Glucuronide
CAS:Formula:C22H30N2O9Color and Shape:White To Off-White SolidMolecular weight:466.49N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate
CAS:N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate (DMNPA) is a synthetic compound with the molecular formula C14H17NO. DMNPA is used as an analytical reference standard for the quantification of N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2thienyl) propanamine HCl by HPLC. DMNPA has been shown to be a metabolite of the drug product, where it is formed from oxidation of the parent drug.Formula:C19H21NOS·C4H6O6Purity:Min. 95%Molecular weight:461.53 g/molVenlafaxine HCl
CAS:Formula:C17H27NO2·HClColor and Shape:White To Off-White SolidMolecular weight:277.41 36.46Sibutramine N-Oxide HCl
Formula:C17H26ClNO·HClColor and Shape:White To Off-White SolidMolecular weight:295.86 36.46rac-Atomoxetine EP Impurity D HCl (Atomoxetine USP Related Compound B)
CAS:Formula:C17H21NO·HClMolecular weight:255.36 36.46Duloxetine Impurity 13 Oxalate
CAS:Formula:C19H21NOS·C2H2O4Color and Shape:White LiquidMolecular weight:311.44 90.04Atomoxetine EP Impurity A HCl ((R)-Isomer)
CAS:Formula:C16H19NO·HClColor and Shape:White To Off-White SolidMolecular weight:241.34 36.46Venlafaxine
CAS:Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD),Formula:C17H27NO2Purity:99.20%Color and Shape:White Solid CrystallineMolecular weight:277.4(S)-Duloxetine Phthalamide
CAS:Formula:C26H23NO4SColor and Shape:White To Off-White SolidMolecular weight:445.53N-Nitroso-N,O-Didesmethyl Venlafaxine (Mixture of Diastereomers)
Formula:C15H22N2O3Molecular weight:278.35Chloro-Sibutramine HCl
CAS:Formula:C17H25Cl2N·HClColor and Shape:White To Off-White SolidMolecular weight:314.30 36.46Tramadol EP Impurity E HCl (Tramadol USP Related Compound B)
CAS:Formula:C9H17NO·HClColor and Shape:White To Off-White SolidMolecular weight:155.24 36.46Atomoxetine EP Impurity F HCl
Formula:C17H20FNO·HClColor and Shape:Off-White SolidMolecular weight:273.35 36.46O-Desmethyl Venlafaxine-d10
CAS:Formula:C16H15D10NO2Color and Shape:White To Off-White SolidMolecular weight:273.44N-Formyl N,N-Didesmethyl Sibutramine
CAS:Formula:C16H22ClNOColor and Shape:White To Off-White SolidMolecular weight:279.81Tramadol 1,2-Olefin Hydrochloride (1-(3-Methoxyphenyl)-2-(dimethylaminomethyl) cyclohex-1-ene hydrochloride)
CAS:Amino-naphthols and other amino-phenols, their ethers and esters, other than those cont more than one kind of oxygen function; salts thereof, nesoiFormula:C16H23NO·HClColor and Shape:White SolidMolecular weight:245.17796Tramadol Impurity 7 HCl
Formula:C16H25NO3·HClColor and Shape:White To Off-White SolidMolecular weight:279.38 36.46N-Nitroso Duloxetine
CAS:Formula:C18H18N2O2SColor and Shape:Colourless To Light YellowMolecular weight:326.413Venlafaxine EP Impurity F HCl
CAS:Formula:C17H25NO·HClColor and Shape:White To Off-White SolidMolecular weight:259.39 36.46Duloxetine Impurity 15 (α-Hydroxy)
CAS:Formula:C18H19NOSColor and Shape:Off-White SolidMolecular weight:297.42Venlafaxine Impurity F HCl
CAS:Controlled Productb-1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine is a drug product that is used in the development of drugs. It is a metabolite of cyclizine and has been shown to have antihistaminic effects. This chemical compound is an impurity standard for HPLC analyses of other substances. b-1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine has also been shown to be a synthetic intermediate in the synthesis of pharmaceuticals.Formula:C17H25NO·HClPurity:Min. 95%Molecular weight:295.85 g/molpara-Hydroxy L-Milnacipran
CAS:Formula:C15H22N2O2Color and Shape:White To Off-White SolidMolecular weight:262.35(S)-Duloxetine succinamide
CAS:Duloxetine succinamide is a chromatographic, solid, acidic compound. It has been synthesized by reacting (S)-duloxetine hydrochloride with succinic anhydride in the presence of triethylamine and acetonitrile. The reaction mixture was purified by high-performance liquid chromatography to produce the desired product. The purity of the compound was confirmed by postulating that it should have a reversed-phase HPLC profile similar to that of duloxetine succinate. Duloxetine succinamide is not soluble in water and is insoluble in organic solvents such as acetone, chloroform, ether, or benzene. The compound is stable at room temperature but decomposes when heated at higher temperatures. !--Formula:C22H23NO4SPurity:Min. 95%Color and Shape:PowderMolecular weight:397.49 g/molAtomoxetine Impurity 5
CAS:Formula:C18H21NO2Color and Shape:White To Off-White SolidMolecular weight:283.374-Hydroxy Atomoxetine Oxalate
CAS:Formula:C17H21NO2·C2H2O4Color and Shape:Off-White SolidMolecular weight:271.36 90.03(1R,2R)-Milnacipran HCl
CAS:Formula:C15H22N2O·HClColor and Shape:White To Off-White SolidMolecular weight:246.36 36.46Venlafaxine EP Impurity E
CAS:Formula:C17H25NO2Color and Shape:White To Off-White SolidMolecular weight:275.391-Fluoronaphthalene
CAS:1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.Formula:C10H7FPurity:Min. 95%Molecular weight:146.16 g/molTramadol Related Compound B (2-[(Dimethylamino)methyl]cyclohexanone hydrochloride)
CAS:Amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof, nesoiFormula:C9H17NO·HClColor and Shape:White PowderMolecular weight:155.13101Venlafaxine EP Impurity C HCl (N,N-Didesmethyl Venlafaxine HCl)
CAS:Formula:C15H23NO2·HClColor and Shape:White To Off-White SolidMolecular weight:249.35 36.46Venlafaxine Related Compound 4 (S-4-(1-(1-Hydroxycyclohexyl)-2-((4-hydroxyphenylethyl) amino) ethyl) phenol)
Formula:C22H29NO3Molecular weight:355.484'-Hydroxy Atomoxetine-d3 Hemioxalate
CAS:Formula:C17H18D3NO2·5C2H2O4Color and Shape:White To Off-White SolidMolecular weight:274.38 0.5*90.03Atomoxetine hydrochloride
CAS:Atomoxetine HCl (LY 139603) is a selective non-stimulant ADHD drug that blocks norepinephrine reuptake, enhancing focus and reducing impulsivity.Formula:C17H22ClNOPurity:99.86%Color and Shape:White SolidMolecular weight:291.82(±)-trans Milnacipran HCl
CAS:Formula:C15H22N2O·HClColor and Shape:Off-White SolidMolecular weight:246.35 36.46Desvenlafaxine Succinate (O-Desmethyl Venlafaxine Succinate)
CAS:Formula:C16H25NO2·C4H6O4Color and Shape:White To Off-White SolidMolecular weight:263.38 118.09N-Nitroso Duloxetine EP Impurity A (N-Nitroso Duloxetine USP Related Compound A)
CAS:Formula:C18H18N2O2SMolecular weight:326.41N,O-Didesmethyl Tramadol Glucuronide (Mixture of Diastereomers)
Formula:C20H29NO8Color and Shape:White To Off-White SolidMolecular weight:411.45N,N-Didesmethyl 1-Hydroxy Sibutramine (Mixture of Diastereomers)
CAS:Formula:C8H8ClNOMolecular weight:267.80Sibutramine Impurity J
CAS:Formula:C15H19ClOColor and Shape:Pale Yellow LiquidMolecular weight:250.77Duloxetine USP Related Compound H
CAS:Formula:C22H23NO4SColor and Shape:White To Off-White SolidMolecular weight:397.49Duloxetine EP Impurity E
CAS:Formula:C18H19NOSColor and Shape:White To Off-White SolidMolecular weight:297.42Duloxetine EP Impurity F HCl
CAS:Formula:C18H19NOS·HClColor and Shape:White To Off-White SolidMolecular weight:297.42 36.464-Hydroxy Duloxetine Acetate
CAS:Formula:C18H19NO2S·C2H4O2Color and Shape:Pale Orange SolidMolecular weight:313.42 60.052,2'-Methylenebis[4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol
CAS:2,2'-Methylenebis[4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol] is a synthetic drug product that is used as a reference standard for HPLC and GC analyses. It is also a metabolite of the drug product 2,2'-methylenebis[4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol], which is used in pharmaceuticals. This impurity standard exhibits analytical properties similar to those of the API impurity. The chemical structure of this compound consists of an aromatic ring with two methyl groups and two methoxy groups attached to it.Formula:C33H50N2O4Purity:Min. 95%Molecular weight:538.76 g/molVenlafaxine EP Impurity G HCl
CAS:Formula:C17H27NO·HClColor and Shape:White To Off-White SolidMolecular weight:261.41 36.46Venlafaxine Impurity 16
CAS:Formula:C17H25NO2Color and Shape:White To Off-White SolidMolecular weight:275.39N,O-Didesmethyl Venlafaxine-13C-d3 ( (Mixture of Diastereomers)
Formula:C1413CH20D3NO2Molecular weight:253.36Desvenlafaxine Fumarate (O-Desmethyl Venlafaxine Fumarate)
CAS:Formula:C16H25NO2·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:263.38 116.07Venlafaxine-d6 N-Oxide
CAS:Formula:C17H21D6NO3Color and Shape:White To Off-White SolidMolecular weight:299.44O-Desmethyl Venlafaxine-d6
CAS:Formula:C16H19D6NO2Color and Shape:White To Off-White SolidMolecular weight:269.42Venlafaxine EP Impurity D-13C-d3 HCl (Venlafaxine USP Related Compound A-13C-d3, N-Desmethyl Venlafaxine-13C-d3 HCl)
CAS:Formula:C1513CH22D3NO2·HClMolecular weight:267.39 36.46Atomoxetine EP Impurity C HCl (Atomoxetine USP Related Compound C (R-Isomer))
CAS:Formula:C17H21NO·HClColor and Shape:White To Off-White SolidMolecular weight:255.36 36.46Venlafaxine Impurity 10
CAS:Formula:C23H31NO2Color and Shape:White To Off-White SolidMolecular weight:353.51O-Desmethyl Venlafaxine Cyclic Impurity
CAS:Formula:C16H23NO2Color and Shape:White To Off-White SolidMolecular weight:261.37Venlafaxine Impurity 13
CAS:Formula:C22H29NO3Color and Shape:White To Off-White SolidMolecular weight:355.48Milnacipran Impurity 20
Formula:C38H46N4O4Color and Shape:White To Off-White SolidMolecular weight:622.81Duloxetine Impurity 20
CAS:Formula:C25H23NO3SColor and Shape:White To Off-White Semi-SolidMolecular weight:417.52Atomoxetine Impurity 4 HCl
Formula:C16H19NO·HClColor and Shape:White To Off-White SolidMolecular weight:241.34 36.46Atomoxetine Impurity 8 HCl
CAS:Formula:C19H25NO2·HClColor and Shape:White To Off-White SolidMolecular weight:299.42 36.461,6-Dehydro Tramadol Hydrochloride (1-(3-Methoxyphenyl)-2-(dimethylaminomethyl) cyclohex-6-ene hydrochloride)
CAS:Amino-naphthols and other amino-phenols, their ethers and esters, other than those cont more than one kind of oxygen function; salts thereof, nesoiFormula:C16H23NO·HClColor and Shape:White PowderMolecular weight:245.17796Milnacipran USP Related Compound C
CAS:Formula:C23H24N2O3Color and Shape:White To Off-White SolidMolecular weight:376.46Venlafaxine Impurity 3 (Venlafaxine Hydroxy Nitrile Impurity)
CAS:Formula:C15H19NO2Color and Shape:White To Off-White SolidMolecular weight:245.32Venlafaxine EP Impurity H
CAS:Formula:C24H33NO3Color and Shape:White To Off-White SolidMolecular weight:383.53Venlafaxine-d6
CAS:Formula:C17H21D6NO2Color and Shape:White To Off-White SolidMolecular weight:283.44Venlafaxine Related Compound 1 (4-(1-Cyclohex-1-en-1-yl)-2-(dimethylamino)ethyl)phenol)
Formula:C16H23NOColor and Shape:White To Off-White SolidMolecular weight:245.374’-Hydroxy Atomoxetine Glucuronide
CAS:Formula:C23H29NO8Color and Shape:Off-White SolidMolecular weight:447.483-(Methylamino)-1-(2-thienyl)propan-1-ol
CAS:3-(Methylamino)-1-(2-thienyl)propan-1-ol is a lipase inhibitor that belongs to the group of 1-fluoronaphthalene. It is an efficient method for the demethylation of 1-fluoronaphthalene, which is used in the synthesis of many pharmaceuticals. The synthesis of this compound was achieved through a kinetic study and confirmed by x-ray crystallography. This compound has been shown to be an analytical method for the determination of impurities in other drugs. 3-(Methylamino)-1-(2-thienyl)propan-1-ol can also be used as a drug substance for other pharmaceuticals and has been shown to inhibit the transfer of chiral centers mediated by enzymes and substrates.Formula:C8H13NOSPurity:Min. 95%Molecular weight:171.26 g/mol(1R,2S)-Milnacipran-d5 HCl (D-Milnacipran-d5 HCl)
CAS:Formula:C15H17D5N2O·HClColor and Shape:Off-White SolidMolecular weight:251.38 36.46Milnacipran-d5 HCl
CAS:Formula:C15H17D5N2O·HClColor and Shape:White To Off-White SolidMolecular weight:251.38 36.46Tramadol EP Impurity C HCl
CAS:Formula:C16H23NO·HClColor and Shape:Off-White SolidMolecular weight:245.37 36.46(S)-O-Desmethyl-Venlafaxine
CAS:Formula:C16H25NO2Color and Shape:White To Off-White SolidMolecular weight:263.38N-Nitroso-N,O-Didesmethyl Venlafaxine-13C-d3 (Mixture of Diastereomers)
Formula:C1413CH19D3N2O3Molecular weight:282.36