Serotonin–Norepinephrine Reuptake Inhibitors (SNRI)

3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride is a sulfoxide that is used as a solvent. It has been used in the synthesis of benzylsulfoxides and solvents for the manufacture of pharmaceuticals. 3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride is also a potent compound, which is structurally similar to benzene but with an additional methyl group. 3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride has been used in the synthesis of melphalan and elemental analysis. The chloride group on its structure makes it soluble in water and organic solvents such as acetonitrile. 3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride can be synthesized by reacting nitric acid with 2-aminothiophenol and dimethylanil

Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.

Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders.

N-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride is a custom synthesis that has been shown to be a metabolite of naphthalene. It has been used as an impurity standard for N-methyl-3-(4-naphthol)-2-[(5-nitrofuran-2-yl)methyl] propanamine and in metabolism studies.

Atomoxetine (HSDB 7352) is a selective norepinephrine inhibitor that may cause an increase in blood pressure by increasing norepinephrine concentrations in

Duloxetine hydrochloride is an SNRI used for depression, anxiety, and pain in diabetes and fibromyalgia.