Hormones in Recombinant Proteins

Applications A metabolite of Spironolactone. References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),

Applications Δ5-Avenasterol is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone. References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)

PTH Protein, Human, Recombinant (Active) is expressed in E. coli with Tag Free. The accession number is P01270.

Stability Light Sensitive Applications A synthetic, nonsteroidal estrogen. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 19, 145 (1990),

Applications Dienestrol is a metabolite of Diethylstilbestrol, a non-steroidal synthetic estrogen derivative. References Liehr, J.G., et al.: Steroids, 40, 713 (1982); Yearley, E. et al.: J. Mol. Struct., 890, 240 (2008);

The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes

Impurity Fluticasone USP Related Compound B Applications An impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory. Fluticasone USP Related Compound B. References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009), Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

Applications 5-Alpha-Dihydrotestosterone (2,2,4,4-D4, 98%) 95% Chemical Purity (cas# 5295-66-9) is a useful research chemical.

Applications Aminosteroid, competitive neuromuscular blocker.

Applications A biologically active labelled metabolite of Desogestrel. References Croxatto, H.B., et al.: Hum. Reprod., 14, 976 (1999), Edwards, J.E., et al.: Brit. J. Fam. Plan., 24, 3 (1999),

Applications Unlabeled Taurohyodeoxycholic Acid (T007900) is a bile acid which stimulates the flow of bile salts, for potential treatment of Irritable Bile Syndrome. References Gnewuch, C., et al.: World J. Gastroenterol., 15, 3134 (2009), Yu, B., et al.: J. Nat. Prod., 72, 24 (2009), Lim, S., et al.: Int. J. Cancer, 126, 1582 (2010),

Applications Isotope labelled intermediate in the synthesis of Dexamethasone (D298800), a glucocorticoid anti-inflammatory agent. References Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009), Rodgers, A., et al.: Chem. Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Applications A labelled derivative of Flumethasone. An antiallergic; anti-asthmatic; anti-inflammatory. References Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

Applications Isotope Labelled 17β-Estradiol 3-O-Sulfate is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors. References Li, W.J., et al.: J. Pharmacol. Exp. Therp., 323, 236 (2007); Schneider, C., et al.: Steroids., 69, 245 (2004);

Applications Ethynyl Estradiol-13C2 is isotope labelled version of Ethynyl Estradiol (E685100) which can be used in biological and analytical studies of simultaneous determination of UV-​filters and estrogens in aquatic invertebrates by modified Quick, Easy, Cheap, Effective, Rugged, and Safe extraction and liquid chromatography tandem mass spectrometry. References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.

Applications A common enironmental pollutant showing weak estrogenic effects. Has been shown to cause harm to the male reproductive system of vertebrates in particular among aquatic species where gonadal intersex, altered sex ratios, and reduced gonad size has been observed. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Nakano, S., et al.: J. Health Sci., 48, 83 (2002), Nishio, E., et al.: Biosci., Biotechnol., Biochem., 69, 1226 (2005), Barber, L., et al.: Aquatic Toxicol., 82, 36 (2007), Vajda, A., et al.: Environ. Sci. Technol., 42, 3407 (2008),

Adiponectin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Applications A labelled metabolite of Exemestane; exerts biological effects as an androgen. References Howell, A., et al.: Lancet, 365, 60 (2005), Goss, P., et al.: Clin. Cancer Res., 10, 5717 (2004), Buzdar, A., et al.: Lancet Oncol., 7, 633 (2006), Coates, A., et al.: J. Clin. Oncol., 25, 486 (2007), Jordan, V., et al.: Steroids, 72, 7 (2007),