Hormones in Recombinant Proteins

Stability Hygroscopic Applications An active agent in the preparation of a pharmaceutical for the treatment of asthma or other respiratory diseases.

Applications A labelled metabolite of Pregnenolone (P712200). References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),

Applications Ulipristal Acetate-d3, is the labeled analogue of Ulipristal Acetate (U700812), a selective progesterone receptor modulator. Ulipristal acetate is used during pregnancy. References Gronemeijer, H. et al.: J. Steroid Biochem., 40, 271 (1991); Spitz, I. et al.: Contraception, 48, 403 (1993); Conneely, O. et al.: Steroids, 68, 771 (2003); Chwalisz, K. et al.: Endocr. Rev., 26, 423 (2005);

Impurity Fluocinolone Acetonide EP Impurity I Applications 14,15-Dehydro Fluocinolone Acetonide is an impurity of Fluocinolone Acetonide (F455800); a glucocorticoid and anti-inflammatory agent. References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964); Emerson, M.V., et al.: BioDrugs, 21, 245 (2007)

Applications 17a-Oxa-D-homo-5β-androst-1-ene-3,17-dione is a metabolite in the urine of men following treatment with Δ1-testololactone, which is an idiopathic oligospermic infertility. Also, it is derived from Androstenedione (A637550), which is a testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic steroid). References Yaeger, R. L., et al.: Drug Metab. Dispos., 13, 107-109 (1985); Walker, V.R., et al.: Anal. Biopchem., 234, 194 (1996), King, D.S., et al.: J. Am. Med. Assoc., 281, 2020 (1999)