Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Products of "Complement System"
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C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated
C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated is expressed in E. coli with N-MBP, C-6xHis-Avi. The accession number is P30993.Color and Shape:Lyophilized PowderMolecular weight:52.8 kDa (Predicted)W-54011
CAS:W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Formula:C30H37ClN2O2Purity:95.62%Color and Shape:SolidMolecular weight:493.08Ref: TM-T17250
1mg85.00€5mg127.00€10mg187.00€25mg335.00€50mg518.00€100mg747.00€1mL*10mM (DMSO)165.00€C1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formula:C16H22Cl3N5Color and Shape:SolidMolecular weight:390.74C5aR2 agonist P32 acetate
C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.Formula:C54H70N16O11·xC2H4O2Color and Shape:SolidMolecular weight:1119.23 (free base)Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formula:C22H15NO4S2Purity:98% - 98.49%Color and Shape:SolidMolecular weight:421.49Iptacopan hydrochloride
CAS:Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.Formula:C25H31ClN2O4Purity:98.32% - 99.87%Color and Shape:SolidMolecular weight:458.98Ref: TM-T9189
1mg59.00€5mg127.00€10mg205.00€25mg371.00€50mg620.00€100mg1,026.00€200mg1,388.00€1mL*10mM (DMSO)128.00€C3a (70-77)
CAS:C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.Formula:C35H61N13O10Purity:98%Color and Shape:SolidMolecular weight:823.94Danicopan
CAS:Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.Formula:C26H23BrFN7O3Purity:99.94%Color and Shape:SolidMolecular weight:580.41Ref: TM-T8509
1mg96.00€2mg136.00€5mg215.00€10mg328.00€25mg557.00€50mg797.00€100mg1,103.00€1mL*10mM (DMSO)274.00€MASP2 Protein, Human, Recombinant (His)
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.Color and Shape:Lyophilized PowderMolecular weight:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.C1QL1 Protein, Mouse, Recombinant (His)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.Color and Shape:Lyophilized PowderMolecular weight:26.9 kDa (predicted)(Rel)-Factor B-IN-5
CAS:(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.Formula:C27H32N2O4Purity:98.53%Color and Shape:SolidMolecular weight:448.55Complement C3 Protein, Mouse, Recombinant (His)
Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:36.34 kDa (predicted); 32.39 kDa (reducing conditions)Greziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidCR1 Protein, Human, Recombinant
CR1 Protein, Human, Recombinant is expressed in E. coli with Tag Free. The accession number is P17927.Color and Shape:Lyophilized PowderMolecular weight:21.6 kDa (Predicted)Complement factor B Protein, Mouse, Recombinant (His)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.Color and Shape:Lyophilized PowderMolecular weight:87.0 kDa (predicted)Cyclosporin A
CAS:Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Formula:C62H111N11O12Purity:99.00% - 99.85%Color and Shape:White PowderMolecular weight:1202.61C1q Protein (human)
C1qProtein (human) serves as a subunit in the complement system. It binds to a variety of ligands from self, non-self, and altered-self, contributing to the balance of the immune system, promoting tissue repair, and defending against pathogens.Formula:C19H24N4O3SColor and Shape:SolidMolecular weight:388.48Complement Factor D/CFD Protein, Human, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Color and Shape:Lyophilized PowderMolecular weight:51.2 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.C1QB Protein, Human, Recombinant (His)
Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system.Color and Shape:Lyophilized PowderMolecular weight:25.2 kDa (predicted); 30 kDa (reducing condition, due to glycosylation)Complement C5 Protein, Cynomolgus, Recombinant (His)
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:188.1 kDa (predicted); 106.3 and 75.8 kDa (reducing conditions)Complement factor D Protein, Rat, Recombinant (His)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternateColor and Shape:Lyophilized PowderMolecular weight:27.8 kDa (predicted)Complement C4-B Protein, Mouse, Recombinant (His)
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway.Color and Shape:Lyophilized PowderMolecular weight:39.0 kDa (predicted)Complement C7 Protein, Human, Recombinant (His)
Complement C7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:92.6 kDa (predicted); 92-98 kDa (reducing conditions)C1q Protein (Mouse)
C1qProtein (Mouse) is a subunit of the complement system. It recognizes a variety of ligands and plays roles in maintaining immune system balance, promoting tissue repair, and defending against pathogens.Color and Shape:Odour SolidCFI Protein, Mouse, Recombinant (His)
CFI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:66.75 kDa (predicted); 126.1 kDa, 59.3 kDa and 46.7 kDa (reducing conditions)C1SB Protein, Mouse, Recombinant (His & Myc)
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system.Color and Shape:Lyophilized PowderMolecular weight:82.4 kDa (predicted)NDT 9513727
CAS:NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Formula:C36H35N3O4Purity:99.21%Color and Shape:SolidMolecular weight:573.68C1QBP Protein, Human, Recombinant (His)
C1QBP Protein, Human, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:24.8 kDa (predicted); 36 kDa (reducing conditions)Complement C5 Protein, Rat, Recombinant (His & Myc)
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:14.0 kDa (predicted)C5AR1 Protein, Human, Recombinant (Cell-Free, His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Purity:90%Color and Shape:Lyophilized PowderMolecular weight:40.7 kDa (predicted)EG01377 2HCl
CAS:EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377Formula:C26H32Cl2N6O6S2Purity:99.56%Color and Shape:SoildMolecular weight:659.6Ref: TM-T11154L
1mg145.00€5mg354.00€10mg540.00€25mg869.00€50mg1,188.00€100mg1,596.00€500mg3,202.00€1mL*10mM (DMSO)512.00€CP-289
CAS:CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.Formula:C30H35ClN2O2Purity:99.85%Color and Shape:SoildMolecular weight:491.06Ref: TM-T60161
1mg115.00€2mg172.00€5mg255.00€10mg374.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,147.00€1mL*10mM (DMSO)305.00€Complement C5a Protein, Mouse, Recombinant, Biotinylated
Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:9 kDa (predicted)C5AR1 Protein-VLP, Human, Recombinant (His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Color and Shape:Lyophilized PowderMolecular weight:41.1 kDa (predicted)Complement C8b Protein, Human, Recombinant (His)
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane ofColor and Shape:Lyophilized PowderMolecular weight:67.0 kDa (predicted)SB290157 trifluoroacetate
CAS:SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).Formula:C24H29F3N4O6Purity:98.93% - 99.89%Color and Shape:SolidMolecular weight:526.51Complement C3 Protein, Cynomolgus, Recombinant (His)
Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:90.3%Color and Shape:Lyophilized PowderMolecular weight:186.40 kDa (predicted)C1s-A subcomponent Protein, Mouse, Recombinant (His)
C1s-A subcomponent Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:76.6 kDa (predicted)C3a Receptor Agonist
CAS:C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.Formula:C27H35N3O2Purity:97.5%Color and Shape:SolidMolecular weight:433.59C1QA Protein, Human, Recombinant (His & Myc)
C1QA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.Color and Shape:Lyophilized PowderMolecular weight:30.7 kDa (predicted)C1s Protein, Human, Recombinant (His)
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.Color and Shape:Lyophilized PowderMolecular weight:76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)C1QA Protein, Mouse, Recombinant (His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Purity:90% - 92%Color and Shape:Lyophilized PowderMolecular weight:25.6 kDa (predicted)Complement C5 Protein, Human, Recombinant (His & FLAG)
Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag.Purity:96.1%Color and Shape:Lyophilized PowderMolecular weight:188.8 kDa (predicted)(Z)-Leukadherin-1
CAS:(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b.Formula:C22H15NO4S2Purity:99.23%Color and Shape:SolidMolecular weight:421.49Complement C8a Protein, Human, Recombinant (His)
Complement C8a Protein, Human, Recombinant (His) is expressed in E. coli.Color and Shape:Lyophilized PowderMolecular weight:65.8 kDa (predicted)C1QL3 Protein, Mouse, Recombinant (His & Myc)
May regulate the number of excitatory synapses that are formed on hippocampus neurons.Color and Shape:Lyophilized PowderMolecular weight:28.6 kDa (predicted)Complement C2 Protein, Human, Recombinant (His)
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:98.6%Color and Shape:Lyophilized PowderMolecular weight:82.5 kDa (predicted)Eculizumab
CAS:Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5Purity:98.20%Color and Shape:LiquidMolecular weight:148 kDaComplement C5 Protein, Cynomolgus, Recombinant
Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells.Color and Shape:Lyophilized PowderMolecular weight:8.41 kDa (predicted); 12.42 kDa (reducing conditions)
