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5-Bromo-4-chloro-3-indolyl a-D-maltopyranoside is a chromogenic substrate used to detect the specific enzymatic activity of alpha-glucosidase. After cleavage, 5-bromo-4-chloro-indoxyl is released, resulting in a blue to blue-green color change in bacterial colonies or media. 5-Bromo-4-chloro-3-indolyl a-D-maltopyranoside is used in Pompe disease screening and glycogen storage disorder diagnosis.

5-Bromo-4-chloro-3-indoxyl oleate is a fluorescent substrate that is used for staining and enzyme substrate. It is a conjugate that is used in environmental testing, food testing, and diagnostics. 5-Bromo-4-chloro-3-indoxyl oleate has a CAS number of 341972-97-2 and its molecular weight is 229.5 g/mol. It's purity is > 98%, with a specific optical rotation of +147° (c=1, CHCl3). This compound can be used as a chromogenic or fluorogenic substrate in bioluminescence assays. 5BRIO3 has been shown to be an excellent ligand for the detection of DNA polymerase I activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂,IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。

Chromogenic substrate specific for α-D-mannosidase. Yields a blue precipitate upon cleavage. Identification of Listeria species.

5-Bromo-6-chloro-3-indoxyl choline phosphate is a chemiluminescent substrate for the detection of bacterial activity. It reacts with an enzyme, luciferase, which is present in a variety of living cells. The reaction produces light. This product has been tested for environmental and food safety by the manufacturer. 5-Bromo-6-chloro-3-indoxyl choline phosphate is used as a diagnostic tool to determine the presence of bacteria in humans, animals, and plants. It can be used to measure levels of bacteria in culture media, water samples, and food products. 5-Bromo-6-chloro-3-indoxyl choline phosphate can also be used as a substrate for enzymes such as phosphatases or esterases that catalyze reactions with substrates with brominated or chlorinated groups.

Applications Carfilzomib (2S,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);

Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.

6-Bromo-2-naphthyl 2-acetamido-2-deoxy-beta-D-glucopyranoside is a chromogenic substrate used for the detection of chitinase activity. Upon hydrolysis by chitinase, it releases a yellow-brown color, which is easily detected by spectrophotometry. This substrate has been used to study chitinases in various organisms, including bacteria, fungi, and insects. It can also be used to quantitate chitinase activity in various biological samples.

The Aldol® 470 N-tosyl-L-alanine ester is a high purity, high quality fluorogenic substrate for the enzyme alkaline phosphatase. It is a conjugate of the tosyl group with L-alanine and has been used as a fluorogenic substrate in various food testing applications. The Aldol® 470 N-tosyl-L-alanine ester also has several other uses including in diagnostic methods, culture media, and enzyme substrates.

Aldol® 495 beta-D-glucuronic acid is a chromogenic and fluorogenic enzyme substrate used for detection of beta-glucuronidase activity. The living cells of Escherichia coli can be reliably detected in growth media containing Aldol® 495 beta-D-glucuronic acid, as beta-glucuronidase occurs almost exclusively in E. coli. Aldol® 495 beta-D-glucuronic acid can also be in GUS reporter assays. Aldol® 495 beta-D-glucuronic acid can be used in liquid culture and solid media, and is suitable for use under aerobic and anaerobic conditions. Upon exposure to active beta-glucuronidase, Aldol® 495 beta-D-glucuronic acid develops orange colour and green fluorescence.

A substrate for visualising alkaline phosphatase activity. Produces a red colored insoluble end product that is detected visually, when used together with nitroblue tetrazolium. The substrate system is versatile and functions in a variety of applications, including Northern, Southern, and Western blotting, in situ hybridization, ELISAs and immunohistochemistry. DMF soluble.

5-Bromo-4-chloro-3-indolyl b-D-fucopyranoside is a chromogenic substrate used is for the enzyme beta-fucosidase.

Bestatin (Ubenimex) competitively inhibits many aminopeptidases. Bestatin is a microbial metabolite and dipeptide with immunomodulatory and antitumor effects.