Natural and semi-synthetic antibiotics
Natural and semisynthetic antibiotics are characterised by chemical structures with heterocyclic rings and active functional groups that inhibit the growth of microorganisms. Their structures allow them to interact with vital bacterial processes, making them useful treatments for bacterial infections. Semisynthetic antibiotics can be modified to enhance their spectrum of activity or resistance to degradation.
At CymitQuimica, we offer high-quality natural and semisynthetic antibiotics for research in microbiology and pharmaceutical development.
Products of "Natural and semi-synthetic antibiotics"
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Dicloxacillin Sodium EP Impurity A HCl (Mixture of Diastereomers)
Formula:C19H19Cl2N3O6S·HClColor and Shape:White To Off-White SolidMolecular weight:488.34 36.46Emamectin Benzoate
CAS:Formula:C49H75NO13(B1a)C48H73NO13(B1b)Molecular weight:886.13 (B1a); 872.11 (B1b)Cefepime EP Impurity E Chloride (Cefepime USP Related Compound E)
CAS:Formula:C13H20N3O3S·ClMolecular weight:298.39 35.45Cefamandole Sodium Salt
CAS:Formula:C18H17N6O5S2·NaColor and Shape:White To Off-White SolidMolecular weight:461.49 22.99Cefdinir Impurity 2 (Thiazolylacetylglycine Oxime)
CAS:Formula:C7H8N4O4SColor and Shape:Off-White SolidMolecular weight:244.23Posaconazole Related Compound A
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C37H42F2N8O4Color and Shape:White PowderMolecular weight:700.32971Sulbactam EP Impurity A (Sulbactam USP Related Compound A)
CAS:Formula:C5H11NO4SColor and Shape:White To Off-White SolidMolecular weight:181.21Chloramphenicol 3-Acetate
CAS:Controlled ProductFormula:C13H14Cl2N2O6Color and Shape:NeatMolecular weight:365.176-Epi Doxycycline
CAS:Impurity Doxycycline Related Compound A Stability Hygroscopic, Light Sensitive, Temperature Sensitive Applications 6-Epi Doxycycline is an antibiotic used in the treatment of bacterial and certain parasitic infections. Doxycycline Related Compound A Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Jutglar, M., et al.: J. Pharm. Biomed. Anal., 159, 60 (2018); Metsemakers, W., et al.: J. Control. Release, 209, 47 (2015)Formula:C22H24N2O8Purity:>90%Color and Shape:YellowMolecular weight:444.43Cefazedone Impurity 6
CAS:Formula:C17H15Cl2N3O7SColor and Shape:White To Off-White SolidMolecular weight:476.28Tilmicosin phosphate
CAS:Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease.Formula:C46H83N2O17PPurity:95% - 95.29%Color and Shape:Light Yellow PowderMolecular weight:967.1Cefminox Sodium Impurity 3
Formula:C16H21N7O7S3Color and Shape:White To Off-White SolidMolecular weight:519.57Aztreonam USP Related Compound B (Open-ring Desulfated Aztreonam)
CAS:Formula:C13H19N5O6SColor and Shape:White To Off-White SolidMolecular weight:373.38Amphotericin B Methyl Ester 90%
CAS:Controlled ProductApplications Amphotericin B Methyl Ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B Methyl Esterin is a cholesterol binding compound that showed inhibiton of human immunodeficiency virus type 1 (HIV-1). References Waheed, A.A. et al.: J. Biol. Chem., 281, 28699 (2006); Waheed, A. et al.: J. Virol., 82, 9776 (2008); Waheed, A., et al.: J. Biol. Chem., 281, 28699 (2006)Formula:C49H77NO16Purity:>80%Color and Shape:Dark Yellow To Dark OrangeMolecular weight:936.13Destomycin A
CAS:Destomycin A, an aminoglycoside antibiotic, exhibits activity against bacterial (Gram-positive and Gram-negative), antifungal, and anthelmintic agents. It inhibits peptide synthesis in Escherichia coli cells and stimulates adenylate cyclase in animal tissues.Formula:C20H37N3O13Color and Shape:SolidMolecular weight:527.52p-Nitrobenzyl 6-(1’-Hydroxyethyl)-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate
CAS:Controlled ProductApplications Imipenem intermediate.Formula:C16H16N2O7Color and Shape:NeatMolecular weight:348.31Piperacillin Sulfoxide
CAS:Formula:C23H27N5O8SColor and Shape:White To Off-White SolidMolecular weight:533.56Potassium Clavulanate EP Impurity M
CAS:Formula:C8H20N2OColor and Shape:Colorless LiquidMolecular weight:160.26Chlortetracycline hydrochloride
CAS:Chlortetracycline HCl (Isphamycin): broad-spectrum, bacteriostatic, halts protein synthesis in bacteria and protozoa.Formula:C22H23ClN2O8·HClPurity:99.68%Color and Shape:Odorless Yellow SolidMolecular weight:515.35Amoxicillin EP Impurity J Disodium Salt (Amoxicillin USP Related Compound J Disodium Salt, Amoxicillin Dimer Impurity Disodium Salt) (Mixture of Diastereomers)
CAS:Formula:C32H38N6O10S2·2NaMolecular weight:728.79 2*22.99Cefadroxil Impurity 4 (Mixture of Diastereomers)
Formula:C24H24N4O7SColor and Shape:White To Off-White SolidMolecular weight:512.54Clindamycin Phosphate EP Impurity F
CAS:Formula:C18H35N2O9PSColor and Shape:White To Off-White SolidMolecular weight:486.52Piperacillin-d5 (N-ethyl-d5)
CAS:Formula:C23H22D5N5O7SColor and Shape:White To Off-White SolidMolecular weight:522.59Azithromycin Impurity 2
Formula:C38H70N2O14Color and Shape:White To Off-White SolidMolecular weight:778.98N-[(2S)-3-Amino-2-hydroxypropyl]-N-(3-fluoro-4-morpholinophenyl)acetamide Hydrochloride
CAS:Color and Shape:Neat2,5-Pyrazinediethanol
CAS:Controlled ProductImpurity Clavulanate Potassium EP Impurity A Applications 2,5-Pyrazinediethanol (Clavulanate Potassium EP Impurity A) is an impurity of Clavulanic acid (C563750). High concentrations of Clavulanic acid but not of its degradation products decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus. References Zupke, C., et al.: Biotechnol. Prog., 10, 489 (1994), Finlay, J., et al.: J .Antimicrob. Chemother., 52, 18 (2003), Alper, H., et al.: Science, 314, 1565 (2006), Brethauer, S., et al.: Biotechnol. Bioeng., 98, 356 (2007),Formula:C8H12N2O2Color and Shape:Beige To OrangeMolecular weight:168.19Posaconazole Impurity 72
Formula:C54H59F2N11O6Color and Shape:White To Off-White SolidMolecular weight:996.13N-Nitroso Meropenem EP Impurity A Disodium Salt
Formula:C17H24N4O7S·2NaMolecular weight:428.46 2*22.99Cephalosporin C Sodium Salt
CAS:Formula:C16H20N3O8S·NaColor and Shape:White To Off-White SolidMolecular weight:414.42 22.99Bacitracin EP Impurity H Ditrifluoroacetate
CAS:Formula:C65H96N16O17S·2C2HF3O2Molecular weight:1405.64 2*114.02Cefdinir Related Compound B ((6R,7R)-7-[2-(2-amino-4-thiazolyl)acetamido]-8-oxo-3-vinyl-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C14H14N4O4S2Color and Shape:Yellow Orange Light Brown PowderMolecular weight:366.04565Amikacin Impurity 4
CAS:Formula:C16H32N4O9Color and Shape:White To Off-White SolidMolecular weight:424.45Piperacillin EP Impurity E (Piperacillin USP Related Compound E)
CAS:Formula:C6H10N2O2Color and Shape:Off-White SolidMolecular weight:142.16Cefprozil EP Impurity H
Formula:C26H26N4O7SColor and Shape:White To Off-White SolidMolecular weight:538.58Posaconazole Impurity 113
CAS:Formula:C36H40F2N8O5Color and Shape:White To Off-White SolidMolecular weight:702.76Penicillamine Related Compound 2
Formula:C12H14N2O6S2Color and Shape:Off-White SolidMolecular weight:346.37Besifloxacin Impurity 1
Formula:C19H21ClFN3O3·HClColor and Shape:Pale Yellow SolidMolecular weight:393.85 36.46Temocillin disodium
CAS:Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity and can be used to study urinary tract infections.Formula:C16H16N2Na2O7S2Purity:92.30%Color and Shape:SolidMolecular weight:458.4212-Deoxy Roxithromycin
CAS:Controlled ProductFormula:C41H76N2O14Color and Shape:NeatMolecular weight:821.05Cefaclor-d5 Hydrate
CAS:Controlled ProductApplications Second-generation labelled cephalosporin antibiotic. Antibacterial. References Gray, B.M., et al.: Antimicrob. Agents Chemother., 13, 988 (1978), Lorenz, L.J., et al.: Anal. Profiles Drug Subs., 9, 107 (1980), Hori, R., et al.: J. Pharm. Pharmacol., 40, 646 (1988),Formula:C15H9D5ClN3O4S•x(H2O)Color and Shape:NeatMolecular weight:372.84 + x(18.02)Anidulafungin Ring Opening Impurity (Mixture of Diastereomers)
Formula:C58H73N7O17Molecular weight:1140.25Amoxicillin EP Impurity I
CAS:Formula:C8H9NO3Color and Shape:White To Off-White SolidMolecular weight:167.16Lomefloxacin Impurity 7
CAS:Formula:C19H23F2N3O3Color and Shape:White To Off-White SolidMolecular weight:379.41N-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]acetamide
CAS:N-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]acetamide is an impurity in a high purity analytical reference standard of 3-fluoro-4-(4-morpholinyl)aniline. It is also a metabolite that may be present in drug products containing 3-fluoro-4-(4-morpholinyl)aniline as the active ingredient, such as fluoroquinolones. N-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]acetamide has been shown to inhibit DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibFormula:C15H22FN3O3Purity:Min. 95%Molecular weight:311.35 g/molCeftazidime EP Impurity A
CAS:Formula:C22H22N6O7S2Color and Shape:Off-White SolidMolecular weight:546.57Bacitracin EP Impurity M Tritrifluoroacetate
Formula:C66H101N17O16S·3C2HF3O2Color and Shape:White To Off-White SolidMolecular weight:1420.70 3*114.02Tiamulin EP Impurity F Fumarate
Formula:C28H47NO4S·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:493.76 116.07Cefepime Impurity 9
Formula:C8H10N4O3S·C8H12N4O4SColor and Shape:Pale Yellow SolidMolecular weight:242.25 260.27Cefpirome sulfate
CAS:Cefpirome sulfate (HR-810 sulfate) is a fourth generation cephalosporin antibiotic.Formula:C22H24N6O9S3Purity:97.52%Color and Shape:White Or Off White Crystalline PowderMolecular weight:612.66Posaconazole Impurity 8
Formula:C29H37N5O3Color and Shape:White To Off-White SolidMolecular weight:503.65Thiazolylacetyl Glycine Oxime Acetal ((Z)-2-(2-Aminothiazol-4-yl)-N-(2,2-dihydroxyethyl)-2-(hydroxyimino)acetamide)
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFormula:C7H10N4O4SColor and Shape:Yellow Pale Yellow SolidMolecular weight:246.04228Cefotaxime EP Impurity A (Cefetamet)
CAS:Formula:C14H15N5O5S2Color and Shape:White To Off-White SolidMolecular weight:397.42Cefcapene Impurity 1
Formula:C16H16N4O4S2Color and Shape:White To Off-White SolidMolecular weight:392.45Meropenem trihydrate
CAS:Meropenem trihydrate (SM 7338 trihydrate) with broad-spectrum antibacterial activity,is a carbapenem antibiotic.Formula:C17H31N3O8SPurity:99.63%Color and Shape:SolidMolecular weight:437.51Cefotiam Impurity 20
CAS:Formula:C17H27N9O4S3Color and Shape:Pale Orange SolidMolecular weight:517.64Sultamicillin EP Impurity C (Ampicillin, Piperacillin EP Impurity A)
CAS:Formula:C16H19N3O4SMolecular weight:349.41
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