Carbohydrates and glycoconjugates

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Applications Labelled Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase. References Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Applications A fluorinated derivative of Erythromycin (E649950). A macrolide antibiotic. References Labro, M. et al.: Macrolide Antibiot., 37 (2002); Lo Bue, A.M. et al.: J. Chemother., 13, 255 (2001); Fera, M.T. et al.: Int. J. Antimicrob. Agents, 17, 151 (2001);

1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] is a complex carbohydrate that contains a fluorinated sugar. It is synthesized from a monosaccharide and an oligosaccharide and glycosylated with a polysaccharide. The compound has been modified to include methylation and click modification. 1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] can be purchased in high purity from the CAS registry number of 538570-75-6.

Found in milk with immunoprotective effects against pathogens in newborns and aids development and maturation of the immune system and gut microbiota. Suppresses adhesion and infectivity of bacteria and viruses, such as influenza viruses, HIV-1 and rotaviruses. Inhibits binding of cholera toxin.

Applications Isotope labelled Fructose1,6-bisphosphate is an intermediate that lies within the glycolysis metabolic pathway and is also an allosteric activator of pyruvate kinase. References Hinder, L.M., et al.: J. Endocriol., 216, 1 (2013); Takubo, K., et al.: Cell. Stem. Cell., 12, 49 (2013); Kalam, Y., et al.: Clin. Toxciol., 50, 546 (2012);

NA2 is a glycan that is a specific antigen binding molecule. It binds to the CD20 receptor on the surface of human B lymphocytes, which are involved in the development of cancer and inflammatory diseases. NA2 can be used for the treatment of these diseases, as well as cancers that express CD20 receptors. NA2 is generated from endogenous molecules that have been modified by introducing galactose into the carbohydrate backbone. These molecules also form a linker with bendamustine, which is an anticancer drug.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

The blood group H disaccharide is a custom synthesis, complex carbohydrate with an Oligosaccharide and CAS No. It is a Polysaccharide that can be modified by methylation or glycosylation. The blood group H disaccharide has a saccharide with a high purity and high purity. It is fluorinated at the 2' position of the sugar moiety in the backbone. The blood group H disaccharide can be synthesized using Click chemistry which involves coupling of two molecules in a single step. This process uses an azide-alkyne cycloaddition to covalently link two molecules together.

Chondroitin sulphate tetrasaccharide ammonium salt is a synthetic glycosaminoglycan that is used to study the structure, function and interactions of glycosaminoglycans. The polysaccharide is composed of four sugars: glucuronic acid, galactose, N-acetylgalactosamine and glucosamine. The chemical structure of this compound is characterized by its high purity, low viscosity and excellent solubility in water. It can be custom synthesized with any desired degree of substitution (0% to 100%). This product can be used as an additive in cosmetics or as a reagent in biochemistry experiments.

Applications: Laninamivir (L174000) prodrug; a novel long-acting neuraminidase inhibitor. References Neumann, G., et al.: Nature, 459, 931 (2009), Yamashita, M., et al.: Antimicrob. Agents Chemother., 53, 186 (2009),

N-acetyllactosamine is a monosaccharide that belongs to the group of n-acetyllactosamine. It can be found in the form of an agglutinin, lactose, and lectin. The conformation of this molecule is an equilibrium between its alpha and beta forms. The pyridine can act as an acid catalyst for the alpha conformation. There are two forms of this molecule: one synthesized from D-glucose and one synthesized from D-galactose. 1,6-Anhydro-4-O-b-D-galactopyranosyl-b-D-glucopyranose is synthesized from D-glucose. Oligosaccharides containing this molecule have been expressed in Saccharomyces cerevisiae cells and purified by affinity chromatography on columns that contain immobilized antibody to human serum albumin. This molecule has been shown

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

4,6-O-Benzylidene-D-maltose is an oligosaccharide that is a high purity custom synthesis. It has a Click modification and can be synthesized using the Fluorination and Glycosylation reaction. 4,6-O-Benzylidene-D-maltose is soluble in water and ethanol, but insoluble in ether. This product is listed as CAS No. 93417-41-5 and has a Methylation modification. 4,6-O-Benzylidene-D-maltose is also found in saccharides, carbohydrates, and complex carbohydrates.

D-Mannopyranose (Mannose) is a hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

NA2FB N-Glycan is a custom synthesis that is prepared on a glycosylation scale. The monosaccharide units are linked by alpha-1,6 or alpha-1,3 glycosidic bonds to form a linear chain. The saccharides are attached to each other via the formation of beta-1,4 glycosidic bonds. NA2FB N-Glycan has a high purity and modification. It is available in various forms such as oligosaccharide, polysaccharide, saccharide and carbohydrate. This product can be used for research purposes or as raw material in the production of medicine.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

The conformation of the 2-[[2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-βDglucopyranosyl)-βDglucopyranosyl]oxy]ethyl]carbamic acid phenylmethyl ester molecule has been studied by X-ray crystallography. The molecule adopts a chair conformation with the two acetyl groups occupying equatorial positions. The molecule is planar with an angle of 110° between the NH and CO axes. The calculated electron diffraction pattern was in good agreement with the experimental data. The analysis yielded a set of independent amplitudes for each reflection that were analysed to give structure constants and electron distributions.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Lewis Y-O-(CH2)8-biotin is a carbohydrate with the chemical formula (CHO)(CO)3OH. It is a methylated and glycosylated oligosaccharide that has been custom synthesized for use in biotechnology applications. Lewis Y-O-(CH2)8-biotin has been fluorinated at the C5 position to improve its stability and prevent hydrolysis, which may be due to its high purity. This carbohydrate is not commercially available and must be custom synthesized.

3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactose is a synthetic glycosylation of galactose and acetamide. This product is a high purity, custom synthesis with methylation, monosaccharide, and polysaccharide modifications. 3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactose is available in bulk quantities.

Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarotetraose is reported to have potential for novel cosmeceuticals.

Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.

Applications Uridine-2-13C-1,3-15N2 is labelled Uridine (U829910) which is a nucleoside widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA) References Lorine, P., et al.: J. Biol. Chem., 178, 439 (1949); Grakoui, A., et al.: J. Virol., 63, 5216 (1989); Strauss, J., et al.: Microbiol. Rev., 58, 491 (1994); Lin, Y., et al.: Virology, 292, 78 (2002);

Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Anti-Human cytomegalovirus (HCMV) Glycoprotein B/gB Antibody-Biotin (6W231) is a Biotin-conjugated Rabbit antibody targeting Human cytomegalovirus (HCMV) Glycoprotein B/gB. Anti-Human cytomegalovirus (HCMV) Glycoprotein B/gB Antibody-Biotin (6W231) can be used in ELISA.

Neu5Ac(a2-6)Gal(b1-4)GalNAc is a synthetic, fluorinated monosaccharide. It is an oligosaccharide that has been custom synthesized and glycosylated. It is a complex carbohydrate that has been modified with methylation and click chemistry. Neu5Ac(a2-6)Gal(b1-4)GalNAc has CAS number 383365-43-3. This product is available in high purity and can be used in the synthesis of polysaccharides.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

2-O-a-D-Glucopyranosyl-D-galactopyranose is a synthetic monosaccharide that can be used as a glycosylate building block in the synthesis of oligosaccharides. It has been fluorinated, methylated, and click modified. This high purity material is available for custom synthesis. 2-O-a-D-Glucopyranosyl-D-galactopyranose is also known by its CAS number 7368-73-2.

2-Acetamido-4-O-[2-acetamido-4-O-(b-D-glucopyranosyl)-3,6-di-O-(a-D-mannopyranosyl)-2,6-di-O-(a,b,c,d)-D mannopyranosyl]-2,6-di-O-(a,b,c,d)-D mannopyranosyl]-2 deoxy -b D thioglucopyranose is a carbohydrate that belongs to the class of saccharides. This compound is modified with fluorination and methylation and can be custom synthesized. It has high purity and can be glycosylated or click modified.

Beta-gentiobiose octaacetate is a macrocyclic structure that is glycosidated with an antigen. It has a neutralizing effect on the biological properties of the antigen. Beta-gentiobiose octaacetate has shown antitumour activity in animals, which may be due to its ability to inhibit tumor cell proliferation. Beta-gentiobiose octaacetate also has high fluidity and can be used as an oligosaccharide antigen in biological research. The molecule has a constant molecular weight of 400 Da and is conjugated with proton, which makes it useful for electron microscopy.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Stability Hygroscopic Applications Vitexin is a phenolic glycoside drug that shows anti-stress activity. It also shows possible application as an anti-diabetic. References Gupta, P. et al.: Bioorg. Med. Chem., 21, 1116 (2013); Tao, Y. et al.: J. Pharm. Biomed. Anal., 78, 190 (2013);

Sodium Tetragalacturonate (α-1,4 sodium tetrgalacturonate) is derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides, restore development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

N-Glycolylneuraminic acid-spacer-BSA is a synthetic, monosaccharide oligosaccharide, complex carbohydrate. The glycosylation of BSA with N-glycolylneuraminic acid has been shown to be an effective method for the protection of biomolecules against fluoroquinolones. Glycosylation with N-glycolylneuraminic acid can be used as a method for the protection of biomolecules from fluoroquinolone antibiotics and other chemical reagents that are known to react with sugars.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Applications Contained in tobacco flavor additives. References Sumoto, K., et al.: Chem. Pharm. Bull., 39, 792 (1991), Shimamura, T., et al.: Biosci., Biotechnol., Biochem., 67, 295 (2003),

Bulk sweetener; viscosity/bodying agent; humectant; cryoprotectant

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Please enquire for more information about N-Glycolylneuraminic acid dimer sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Remogliflozin is an effective sodium-glucose transporter 2 inhibitor (Kis = 12.4 and 26 nM for human and rat SGLT2, respectively).

Applications D-Xylose-1,2,3,4,5,5'-C-d6 is a labeled analog of D-Xylose, which is used in diagnostic malabsorption tests as well as in the production of Furfural. References Ehrenpreis E.D. et al.: J. Acquir. Immune. Defic. Syndr., 5, 1047 (1992); Sérgio L. et al.: Cat. Comm., 9, 2144 (2008);

Stability Store in freezer Applications Prepared by acetolysis of chitin. Studies have shown this compound to have anti tumor effects. References Barker, S.A., et al.: J. Chem. Soc., 2218 (1958); Suzuki, K., et al.: Carbohydrate Research, 151, 403 (1986)

N-Propyl b-lactoside is a synthetic sugar that belongs to the group of complex carbohydrates. It is a modification on the saccharide that is made by methylation, glycosylation and carbonylation. N-Propyl b-lactoside is synthesized from the monosaccharides glucose, galactose and fructose with the help of click chemistry. This product has high purity, fluorination and synthetic properties.

A-BSA is an antibody that competes with the blood group antigen for binding to erythrocytes. The A-BSA is immobilized on a microtitre plate and incubated with the blood group antigen and human blood group antiserum. The concentration of A-BSA in the solution is determined by measuring the enzyme-linked immunosorbent assay (ELISA) signal using a spectrophotometer. This measurement is used to determine the concentration of blood group antigen in the sample.

1,6-Anhydro-b-D-cellopentose is a synthetic cello-oligomer