Carbohydrates and glycoconjugates

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Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

GM1-biotin ganglioside (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue, ceramide linked β to position 1 on the reducing terminal glucose residue, and biotin to position 5 on sialic acid (Ledeen, 2009). GM1 ganglioside is abundant in all mammalian brains where it covers 10%-20% of the total ganglioside mixture. It is found in epithelial membranes and is a key element for bacterial toxicity and viral infection as it is the intestinal receptor for the cholera toxin, the B-subunits of heat-labile toxin, rotavirus, and simian virus 40. GM1 ganglioside functions as a neurotrophic and neuroprotective compound, and has been used therapeutically for diabetic and peripheral neuropathies. GM1 ganglioside also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).

CO2-philic compound with uses in pharmaceuticals and CO2-based processes

a1-3,a1-6-Mannotriose-BSA is a carbohydrate that is synthesized by the modification of maltotriose with a fluorinated alcohol. It is an oligosaccharide made up of three glucose units linked together in a 1,3 configuration and one glucose unit linked together in a 1,6 configuration. The molecular weight of this carbohydrate is 793 Daltons. This product has been shown to be high purity and custom synthesis for use in research.

Applications cis-Etoposide is an anticancer agent that has half-life of 2 days at pH 7.4 and 37° resulting in the loss of 90% of the active drug within 1 week during in vitro incubations. References Mader, R. M., et al.: Cancer Chemotherapy and Pharmacol., 27, 354 (1991)

This is a custom synthesis of a complex carbohydrate. The CAS number is not available and the polysaccharide has been modified. It has been glycosylated, methylated, and fluorinated. It is high purity and the sugar sequence is a custom synthesis.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

3-O-Acetyl-1,6-anhydro-2-azido-2',3'-di-O-benzyl-4',6'-O-benzylidene-2-deoxy-b,D cellobiose is a fluorinated oligosaccharide that can be customized for a variety of applications. The sugar unit contains an acetyl group on the C1 position and an azido group at the C2 position. This compound has been subjected to click chemistry in order to form a covalent bond with 4,6'-O-benzylidene 2,3'-dideoxy b,D cellobiose.

Hyaluronate fluorescein is a synthetic, high purity, custom-synthesized molecular weight of 50kDa. It is a complex carbohydrate with a sugar backbone and many attached monosaccharides. Hyaluronate fluorescein has been modified by methylation and glycosylation. This product can be used for fluorescent labeling of oligosaccharides and carbohydrates.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Guaifenesin (Guaiphenesin) is an expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Applications β-Sitosterol and β-sitosteryl-β-D-glucoside were isolated as analgesic constituents from the leaves of Mentha cordifolia Opiz. References Tanaka, et al.: J. Biochem., 17, 483 (1933), Nigro, N.D., et al.: J. Natl. Cancer Inst., 69, 103 (1982),

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Methyl 2-acetamido-2-deoxy-3-O-(a-D-galactopyranosyl)-a-D-galactopyranoside is a synthetic, fluorinated glycoside that is used as a building block for the synthesis of complex carbohydrates. Methyl 2-acetamido-2-deoxy-3-O-(a-D-galactopyranosyl)-a-D-galactopyranoside can be used in either Click or Fluorination reactions to synthesize oligosaccharides and monosaccharides. It has been shown to react with ethylene glycol to form methyl 2,6 -O-[(3,4,5,6 -tetra-O-acetyl-β-D-galactopyranosyl)α -L-idopyranosyl]-α -L-idopyranose. Methyl 2,6 -

NA2F Glycan is a custom synthesis that is used in the identification and quantification of methylated polysaccharides. It is a synthetic modification of a natural glycosylation reaction. The NA2F Glycan is synthesized by 2-AB labelled Methylation, saccharide, Polysaccharide, CAS No., Click modification, Modification, Oligosaccharide, Custom synthesis, Glycosylation, High purity, Carbohydrate, sugar, Synthetic, Fluorination with high purity and complex carbohydrate. This product can be used in glycobiology research as a methylation-sensitive probe for the detection of methylated polysaccharides such as glycoproteins and glycolipids.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Man-9 N-glycan is a glycoprotein that is found on the surface of many viruses. It has an oligosaccharide structure, which consists of a mannose and a glucose molecule linked by an alpha-1,3-glycosidic bond. The Man-9 N-glycan can be found in human serum and is involved in lectin binding to cells. It also has antiviral activity and may be used as a model system for studying glycosidic bonds. This glycan can be broken down into smaller components by methyl glycosides or titration calorimetry, which is a technique for determining the molecular weight of substances. The Man-9 N-Glycan binds to toll-like receptor 2 (TLR2) on the surface of human cells, which activates an antibody response.

MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.

Ex starch-partial hydrolysis,food ingredient, moderatly sweet, easily digested

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Man-7D2 N-glycan is a custom synthesis of mannose. It is a modification of the glycan, which is an oligosaccharide that consists of many monosaccharides linked together. The process of glycosylation involves the addition of one or more sugars to an existing carbohydrate molecule. In this case, the sugar is mannose and it has been modified by fluorination, methylation, and click chemistry. This product can be used as a substitute for natural glycans in research applications. The CAS number for this product is 59569-81-1.

Isosteviol is a natural sweetener with anti-inflammatory, anti-tumor, glucose-lowering, and other health benefits.

Galacto-oligosaccharides (GOS) are a class of oligosaccharides that consist of galactose, galactose derivatives, and glucose. They are found in the human diet as a result of lactose breakdown by gut bacteria. GOS can bind to glycoconjugates in the human body, such as glycoproteins and glycolipids, and have been shown to be effective in preventing the growth of pathogens. Galacto-oligosaccharides are also synthetically produced, using a chromatographic method that separates them into individual sugars, where they can be used for research or diagnostic purposes. The biosynthesis of GOS is also known; it is an enzyme-catalyzed reaction involving calcium ions. This process is regulated by Ca2+ signaling, which leads to an increase in the production of GOS when there is a need for more immune cells or white blood cells.

2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranose (Neu5Ac) is a methylated saccharide that is synthesized by the enzyme glycosylase. The acetamido group on the sugar reacts with the amino group at position 6 of the sugar to form a Schiff base, which then undergoes an elimination reaction to generate 2,6-dideoxygalactose. This product can be modified using click chemistry or other modification techniques such as Glycosylation, High purity, Carbohydrate, sugar, Synthetic, Fluorination and more.

2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-lactosyl fluoride (HAP) is a synthetic compound that has been modified with fluorine and methyl groups. It is a monosaccharide with a glycosylation pattern that includes a terminal glucose unit. HAP has been shown to be an effective carbohydrate in the synthesis of complex carbohydrate structures.

1,6-Anhydrochitobiose is an anhydosugar that can be used in the synthesis of oligosaccharides and polysaccharides

The carbohydrate is a saccharide that is a modification of the monosaccharide. It is synthesized from D-mannose and D-glucose and has a fluorination at the C4 position. The carbohydrate has been custom synthesized for high purity, methylation, glycosylation, and click modification.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Darutoside (Darutin) is a wound treatment that enhances skin elasticity, appearance, and stretch mark reduction by soothing and promoting collagen.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Produced from high maltose syrup by treatment with transglucosidase

D-Maltose monohydrate is a glycosylation product of maltose. It is a complex carbohydrate that has been methylated, fluorinated, and modified with Click chemistry. D-Maltose monohydrate has the CAS number of 3647-20-3 and can be custom synthesized to meet your specifications. This product is free from endotoxins and can be made in high purity.

2,3,1',3',4',6'-Hexa-O-acetyl-6-O-methacryloyl-sucrose is a saccharide that has been modified using methylation and click chemistry. It is also known as hexaacetylsucrose. This product is used in the production of glycoproteins and polysaccharides. 2,3,1',3',4',6'-Hexa-O-acetyl-6-O-methacryloyl-sucrose is a synthetic compound that can be custom synthesized to order. It has high purity and can be ordered in a variety of purities.

Chitosan is the deacetylated form of chitin. The polysaccharide is deacetylated in order to render it soluble, which is then possible at pH values of less than 7 (normally in dilute acid). This then allows the material to be used in a number of industrial applications as a binder and film former.

8-Methoxycarbonyloctyl-3-O-benzyl-2,2'-dideoxy-2,2'-diphthalimido-3',4',6-tri-O-acetyl-b -cellobiose is a cellobiose with an 8 methoxycarbonyl group at the C8 position. It can be used in the synthesis of oligosaccharides and polysaccharides. The compound has been synthesized by methylation, click modification, and fluorination. The CAS number is 106445-30-1. 8MCOBBIOSE has a purity of > 98% and may have a white to off white powder appearance.

Stability Hygroscopic Applications Antibiotic complex produced by Streptomyces kanamyceticus Okami & Umezawa from Japanese soil. Comprised of three components, kanamycin A, the major component, and kanamycins B and C, two minor congeners. Antibacterial.A representative lot contains d4, d5, d6, d7, d8, and d9. References Ito, et al.: J. Antibiot., 17, 189 (1964), Toda, S., et al.: J. Antibiot., 30, 1002 (1977), Claes, P.J., et al.: Anal. Profiles Drug. Subs., 6, 259 (1977),

3-O-(a-L-fucopyranosyl)-D-galactopyranose is a glycosidic residue that is part of the β-D-Galactoside. It is an amino acid that is used to form carbohydrates. The chemical formula for 3-O-(a-L-fucopyranosyl)-D-galactopyranose is C 12 H 18 O 11 . The molecular weight of 3-O-(a-L-fucopyranosyl)-D-galactopyranose is 308.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Monofucosyl (1-2)-iso-lacto-N-octaose I is an oligosaccharide found in human milk

The acetylation of the 2-O-acetamido-1,6-di-O-acetyl-2-deoxy-4-O-(2-acetamido-3,4,6-tri-O-acetyl)-2,3,4,5,6 tetra-, O-(2 acetamido 3,4,6 tri O acetyl) glucopyranoside in the presence of methyl iodide and potassium carbonate yields 2 O -Acetamido 1 6 di O acetyl 2 deoxy 4 0-(2 acetylamino 3 4 6 tri 0 acetyl) glucopyranoside methyl ester. The product is a modification of an oligosaccharide or complex carbohydrate.

Applications (-)-Sweroside is an active ingredient of iridoid glycoside isolated from the flower buds of Lonicera japonica THUNB. (-)-Sweroside has shown anti-inflammatory and analgesic activities. References Luo, Y., et. al.: Chem. Pharm. Bull., 57, 79 (2009); Keun, H., et. al.: Biosci. Biotech. Bioch., 74, 2022 (2010)

Applications Anthracycline antibiotic related to the rhodomycins. Antineoplastic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Yang, Z., et al.: J. Pharmacol. Experim. Ther., 327, 474 (2008), Zhao, Y., et al.: Int. J. Pharm., 379, 90 (2009), Bayne, W., et al.: J. Pharm. Sci., 98, 2540 (2009),

1,2,3-Tri-O-acetyl-5-O-benzoyl-4-C-fluoromethyl-D-ribofuranose is an organic compound. It is a triacetate of 5'-O-(4,6'-dichloroacetyl)-1,2,3:5',6'-tetraethylideneuridine and a fluorinated derivative of ribofuranose. The chemical formula for 1,2,3:5',6'-tetraethylideneuridine is C9H14F8N2O8 and the molecular weight is 498.17 g/mol.

Anti-CD200RLa Antibody-Biotin (5K764) is a Biotin-conjugated Mouse antibody targeting CD200RLa. Anti-CD200RLa Antibody-Biotin (5K764) can be used in ELISA.

GT1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b ganglioside is one of the major gangliosides in neuronal and glial membranes. It interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishiki, 1996), as well as for viruses. A few examples of which include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).