Carbohydrates and glycoconjugates

3-(b-D-Glucopyranosyl)-D-mannose is a sugar that is a component of the complex carbohydrate called glycosaminoglycan. It can be used in the synthesis of oligosaccharides and monosaccharides or as a modification to saccharides. 3-(b-D-Glucopyranosyl)-D-mannose is synthesized through Click modification with fluorination, glycosylation, and methylation. This sugar has CAS No. 27212-79-4 and molecular weight of 360.3 g/mol.

Sialylated oligosaccharide with the ability to inhibit angiogenesis and tumour development by binding to the vascular endothelial growth factor receptor VEGFR-2. Moreover, sialylated N-glycans in intestinal epithelium of chickens were found to carry terminal sialylgalactose, which interacts with influenza viruses during early stages of infection.

Stability Hygroscopic Applications It has carcinostatic activity. References Reynolds, T.M., et al.: Advan. Food. Res., 14, 167 (1965), Szent-Gyorgyi, L.G., et al.: Science, 155, 539 (1967),

Man-7 N-Glycan is a sugar that is composed of an oligosaccharide and a monosaccharide. The oligosaccharide is composed of an alpha-1,6-linked mannose, an alpha-1,2-linked mannose, and a beta-1,2-linked mannose. The monosaccharide is composed of glucose. This sugar has been modified with methylation and fluorination on the mannose side chains. It also contains glycosylation in the form of O-(alpha-D-mannopyranosyl)-(alpha-D-mannopyranosyl)n or O-(alpha-D-mannopyranosyl)-(beta-D-mannopyranosyl)m. A CAS number for this carbohydrate has not yet been assigned because it is custom synthesized. Man 7 N Glycan can be found in nature as a component of glycogen

Disialyl, monofucosyllacto-N-hexaose is a synthetic oligosaccharide also found in human milk

Methyl 2-O-(a-D-galactopyranosyl)-b-D-galactopyranoside is a custom synthesis that is fluorinated at the 2 position. It is an oligosaccharide, polysaccharide, and carbohydrate. The product has been modified with the Click modification and has high purity. It is also a monosaccharide sugar or synthetic sugar. Methyl 2-O-(a-D-galactopyranosyl)-b-D-galactopyranoside can be used in complex carbohydrates and fluorination reactions.

1,2,3,6-Tetra-O-acetyl-4-O-[2,3,6-tri-O-acetyl-4-O-(2,3,4,6 tetra-O-acetyl bDglucopyranosyl)-bDglucopyra nosyl]-bDthioglucopyranose (1) is a sugar with the chemical formula C36H62N8O24. It was first synthesized by the group of L. W. F. Heckel in 1956 and its structure was elucidated by X. Miettinen in 1957. 1 is a complex carbohydrate with a glycosidic linkage to 4 as well as an acetate ester at position 6. The compound has been modified with methyl groups at positions 2 and 3 to form 1,2,3,6 tetra O acetyl 4 O methyl 2 O methyl 3 O methyl 6 O eth

Shortest chain oligosaccharide that can be classified as a maltodextrin. A component of liquid glucose (a commercial sweetener composed of glucose, maltose, maltotriose and maltotetrose).

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Intermediate for synthesis of N-acetyllactosaminic glycans

Applications Capecitabine (C175650) impurity.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

GM2-oligosaccharide (sodium salt) is a trisaccharide (GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the central galactose residue (Ledeen, 2009). The parent GM2 ganglioside is present on neuronal cells and plays a key role in the regulation of dendritogenesis in cortical pyramidal neurons. In lysosomal storage disorders, such as, Tay-Sachs and Sandhoff disease, where hexosaminases A and B are deficient, GM2 ganglioside accumulates in the nervous system (Cachon-Gonzalez, 2018). GM2 ganglioside is also overexpressed in melanomas and other tumours of neuro-ecto origin (Yoshida, 2020). Moreover, the sugar moiety of GM2 ganglioside is a receptor allowing viral infection of cells with reovirus and rotavirus (Zhu, 2018).

Please enquire for more information about [UL-2H7glc]Lactose monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Difucosyl-para-lacto-N-hexaose I is a synthetic oligosaccharide that is used as a model for the longum subsp. of human milk oligosaccharides. The Difucosyl-para-lacto-N-hexaose I oligosaccharide was synthesized from sucrose and alpha-(1,2)-fucopyranosyl chloride, which were then reacted with para-nitrophenyl bromide (PNP). This product has been shown to inhibit the growth of respiratory pathogens in vitro by binding to c-reactive protein. It also binds to the Fc region of immunoglobulins and can act as an adjuvant for vaccines.

Methylation, Custom synthesis, Click modification, CAS No., Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate, High purity, Modification. Monosaccharide sugar. Synthetic. 2-Anhydro-4-O-(a-L-idopyranosyluronic acid 2-sulfate)-D-mannofuranose 6-sulfate trisodium salt is a methylated and modified form of D-mannose. It is a monosaccharide with a molecular weight of 376.34 and a CAS number of 64459-77-5. This product can be used in the synthesis of oligosaccharides or polysaccharides as well as in the production of high purity mannose derivatives with modified linkages.

Useful for selective precipitation of enantiomeric, positional or structural isomersα-Cyclodextrin is used as a fiber ingredient, an odor or flavor masking agent. It is also useful for emulsification applications. It is also used as whipping fiber and emulsifying fiber. It finds application in medical, healthcare and food and beverage applications. It is also used to lower blood low-density lipoprotein cholesterol levels and lower blood triglyceride levels. It plays an essential role in fat free or fat containing dessert compositions and also employed for the reduction or the replacement of egg white in confectionary and bakery applications. Further, it acts as a supramolecular carrier, complexing agent and controlled drug release. In addition to this, it is used to increase the insulin and leptin sensitivity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

4-Methoxyphenyl 4-O-(2,4,6-tri-O-acetyl-3-O-allyl-b-D-galactopyranosyl)-3-O-allyl-b-Dglucopyranoside is a synthetic sugar with a molecular weight of 532. This product can be used in the synthesis of oligosaccharides and monosaccharides. It is also used as an intermediate in glycosylation reactions. This product has not been assigned a CAS number yet.

A custom synthesis of benzyl-6-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-2,3,4-tri-O-benzyl-a-D-mannopyranoside was made with the following modifications: fluorination and methylation. The molecular weight is 636.81 g/mol. It is a white crystalline solid. CAS No.: Benzyl - 6 - O - ( 2 , 3 , 4 , 6 - tetra - O - acetyl - a - D - mannopyranosyl ) - 2 , 3 , 4 - tri - O - benzyl a - D - mannopyranoside

Applications Oseltamivir Namino-fructosyl Conjugate is derived from Oseltamivir Phosphate (O701000), which is an orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug. It is a COVID19-related research product. References Oliyai, R., et al.: Pharm. Res., 15, 1300 (1998), Kim, C.U., et al.: Med. Chem. Res., 8, 392 (1998), Hayden, F.G., et al.: N. Engl. J. Med., 341, 1336 (1999), Treanor, J.J., et al.: J. Am. Med. Assoc., 283, 1016 (2000)

Lacto-N-fucopentaose III-APD-HSA is a custom synthesis, complex carbohydrate that has been modified with methylation and glycosylation. It is an oligosaccharide that is found in human serum albumin. Lacto-N-fucopentaose III-APD-HSA has been shown to have antitumor activity. It also inhibits the growth of bacteria by binding to bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. This compound binds to two sites on the 16S ribosomal RNA of bacteria and can inhibit protein synthesis, leading to cell death by inhibiting production of proteins vital for cell division. Lacto-N-fucopentaose III-APD-HSA has undergone fluorination and click modification. Methylation: A process whereby a methyl group (-CH3) is added to an organic molecule via a chemical

Anti-IL-8/CXCL8 Antibody-Biotin (5K777) is a Biotin-conjugated Mouse antibody targeting IL-8/CXCL8. Anti-IL-8/CXCL8 Antibody-Biotin (5K777) can be used in ELISA.

1,2,3,6-Tetra-O-acetyl-4-O-(2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetylaDglucopyranosyl)-aDglucopyranosyl)-bDthioglucopyra nose is a sugar with the chemical formula C27H42O14. This compound is synthesized by the glycosylation of 1,2,3,6 tetra O acetyl 4 O (2 3 6 tri O acetyl 4 O (2 3 4 6 tetra O acetyl a D glucopyranosyl) a D glucopyranosyl) b D thioglucopyrazine with 2 3 6 tri O acetate 4 O (2 3 4 6 tetra O acetate a D glucopyranoside a D glucopyranoside

DNS-SGN is a synthetic, high purity, methylated, glycosylated, complex carbohydrate. This product is custom synthesized and has been fluorinated with a click modification. DNS-SGN is CAS Number: 598-02-3.

D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol.

G-NGA2 N-glycan is a custom synthesis and modification of the carbohydrate. This product contains a fluorination, methylation, and monosaccharide. The average molecular weight is 1257. G-NGA2 N-Glycan is a saccharide that is synthesized from glucose by glycosyltransferase. It can be modified with a click reaction to form an oligosaccharide or polysaccharide. G-NGA2 N-Glycan has been assigned the CAS number 103584-68-5 and molecular weight of 1257 Da.

Fructononasaccharide is a modification of oligosaccharides that is synthesized from sucrose. It is a complex carbohydrate that has been modified with methylation and glycosylation. Fructononasaccharide is used in the synthesis of polysaccharides, as well as for the production of high-purity, custom-synthesized monosaccharides and disaccharides. Fructononasaccharide can be fluorinated or saccharified to produce different compounds.

Benzyl 4-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-2,3-di-O-benzylb -D-galactopyranoside is a Fluorination and Glycosylation product. It is a Custom Synthesis of Monosaccharide and Oligosaccharide. The CAS number for this product is 106835-99-8.

Blood group B-HSA conjugate useful for raising antibodies

3-O-(2-Acetamido-2-deoxy-a-D-glucopyranosyl)-D-galactose is a synthetic compound that is synthesized by the reaction of 3,4,6-trihydroxypyranose with trifluoroacetic anhydride. The product can be purified to the desired level of purity using preparative HPLC or recrystallization. The CAS number for this compound is 97096-73-6.END>

4-Methoxyphenyl 2,3,6-tri-O-acetyl-4-O-[2,4,6-tri-O-acetyl-3-O-(3,4,6-tri-O-acetyl-2-deoxy-2 -phthalimido)-bDglucopyranosyl]-bDgalactopyranoside is a high purity methylated glycoside of 4 methoxyphenol. The product has been modified by fluorination and Click chemistry to produce a complex carbohydrate. This modification can be used for the synthesis of oligosaccharides and polysaccharides.

Imeglimin hydrochloride (EMD 387008 hydrochloride) is an oral hypoglycemic agent. Imeglimin improves insulin sensitivity.Cost-effective and quality-assured.

Gala1-3(Fuca1-2)Galb1-3GlcNAcb1-3Gal (B antigen pentasaccharide Type I)

Cellotriose is a bifunctional sugar that can be chemically converted to cellobiose and D-cellopentaose. Cellotriose is a component of cellulose, which is the most abundant biopolymer on Earth. Cellotriose is a source of chitin, which is a major component of the exoskeleton of insects and crustaceans. The molecule has been observed using atomic force microscopy to have an amphiphilic nature, in that it has both hydrophobic and hydrophilic regions. Cellotriose has been synthesized in the laboratory for use as an artificial sweetener, but it does not taste as good as sucrose because it lacks the sweetness profile. When heated, cellotriose undergoes a color change from yellow to blue-green due to its ability to form hydrogen bonds with oxygen molecules. This property can be used as a colorimetric test for cellulase activity in solutions.

Metabolized by bacteria in the large intestine

2-Acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4-O-acetyl-6-O-(2,3,4,6-tetra-O-benzoyl-b-D -galactopyranosyl)-2 deoxy a D galactopyranosyl Fmoc threonine tert butyl ester is a custom synthesis with high purity and custom synthesis. This product is recommended for methylation and glycosylation reactions. It is a complex carbohydrate that has been modified by fluorination and saccharide.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Citric acid monohydrate is used in the preparation of citrate buffer in platelets for intravital microscopy. It acts as a pH-control agent in foods, beverages and pharmaceuticals applications. It acts as an iron chelator. In animals, it improves the utilization of nutritional calcium. It is a useful buffer component for antigen and epitope unmasking. It is also used as an acidifier, flavoring agent and chelating agent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Raffinose-sp-biotin is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide. It is available in CAS No. and has the molecular formula C6H14O6. Raffinose-sp-biotin is a polysaccharide with a complex carbohydrate structure.

Used for studies of the D-lactose pathway by non-invasive techniques, using ¹â¹F-NMR spectroscopy or positron emission from the ¹âžF-labeled compound.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Please enquire for more information about Difucosyl-para-lacto-N-hexaose III including the price, delivery time and more detailed product information at the technical inquiry form on this page

Drug carrier for cancer therapy & imaging, biocompatible, soluble, biodegradable

OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay.

Rutinose is a naturally occurring polyphenol found in many plants, including the leaves and bark of rue plants. It is a glycoside derivative that has been shown to inhibit human colorectal adenocarcinoma cells (HL-60) by binding to DNA and inhibiting RNA synthesis. Rutinose also has been shown to have anti-inflammatory effects and has been used in the treatment of metabolic disorders such as diabetes mellitus. Rutinose is a bioactive compound with antioxidant properties that may be related to its ability to bind metal ions, including calcium ions at physiological pH levels. Rutinose also has been shown to have a signal peptide sequence that targets it for secretion into the blood stream, where it may act on brain functions.

Applications N-Butyldeoxynojirimycin Hydrochloride-d9 is labelled N-Butyldeoxynojirimycin Hydrochloride (B691000) which is an inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. References Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984), Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986), Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988), Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997),

Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on the umbilical cord (Weissman, 1954). This octasaccharide ammonium salt and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).