Carbohydrates and glycoconjugates

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Laminarin is a storage glucan and is now used to study it’s interaction with laminarinase as its substrate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of

Stability Air Sensitive, Hygroscopic Applications The active metabolite of Erdosteine (E596050). References Dechant, K., et al.: Drugs, 52, 875 (1996), Braga, P., et al.: Arzneim.-Forsch., 49, 344 (1999), Braga, P., et al.: Antimicrob. Agents Chemother., 43, 1013 (1999),

Applications 2R, 3S-Dihydroxy-4-oxo-butanoic Acid is synthesized from D-Ribonolactone (R416000), which is a sugar lactone as inhibitor of β-galactosidase of E. coli. References Zhang, B., et al.: Science, 284, 974 (1999), Zimmet, P., et al.: Nature, 414, 782 (2001), Verspohl, E., et al.: Planta Med., 68, 581 (2002), Thompson, K., et al.: Science, 300, 936 (2003), Thompson, K., et al.: J. Inorg. Biochem., 98, 683 (2004),

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

3'-Sialyl Lewis x-HSA is a custom synthesis of a high purity, complex carbohydrate that has been modified to include fluorination. This product is synthesized from a monosaccharide and an oligosaccharide. It has been shown to have anti-inflammatory properties and is useful in the treatment of type II diabetes.

The product is a complex carbohydrate with a non-sugar linker. It is synthesized by the reaction of 4-methoxyphenyl 6-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-b-D -galacto)-2,3 -di -O -benzyl -b -D -galactopyranoside with borane in THF and methanol. The product is purified by chromatography on silica gel and characterized by FTIR spectroscopy (KBr).

Methyl (4S)-b-cellobiosyl-4-thio-b-cellobioside is a custom synthesis, modification and fluorination of methyl 4-thioacetate with b-D-cellobiosyl 4-thioacetate. This complex carbohydrate has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1), and can be used as a monotherapy or in combination therapy for HSV1 infections. It inhibits the viral process by inhibiting the viral DNA polymerase and preventing DNA replication. Methyl (4S)-b-cellobiosyl-4-thio-b-cellobioside also inhibits the enzyme glycosyltransferase that is required for HSV1 replication. Methyl (4S)-b - cellobiosyl - 4 - thio - b - cellobioside is a sugar that can be modified with click chemistry to produce different derivatives such as phosph

Non-reducing storage and transport sugar in woody plants; used as a sweetener

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Sialyllacto-N-fucopentaose II is a synthetic oligosaccharide that has been shown to be present in human serum. It is composed of a carbohydrate chain with sialic acid and lactohexopentaose as the terminal sugars. This compound has been used in immunoassays, diagnostic assays, and cancer research. Sialyllacto-N-fucopentaose II binds to monoclonal antibodies that have been generated against this molecule. Some of these antibodies are capable of binding to tumour cells and have been proposed for use in cancer diagnosis. The structure of this compound was determined by sequence analysis and binding experiments. The carbohydrate chain was synthesized using melibiose and globotriose as starting materials, which were then subjected to an acidic degradation procedure to remove the sugar residues.

Citric acid is the most widely used organic acid and pH-control agent in foods, beverages, pharmaceuticals and technical applications. Used in pharmaceutical preparations, especially in effervescent tablets. It is used as a natural preservative. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

T-Antigen-APE-HSA is a custom synthesis, modification, and fluorination of T-antigen. This product has been synthesized by methylation and monosaccharide synthesis. It also contains a saccharide that is glycosylated or modified with polysaccharides. This product is made up of complex carbohydrates that are composed of oligosaccharides and sugar chains.

Applications (8S-cis)-8-Acetyl-10-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione is an tert-butyldiphenylsilyl protected degredation product of Doxorubicin (D194500), an anthracycline antibiotic related to the rhodomycins. References Matsumoto, T., et al.: Chem. Pharma. Bull., 34, 4613 (1986);

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

NGA3F N-Glycan is a custom synthesis product that has been fluorinated, methylated, and modified with a click modification. It is a monosaccharide that can be found in the form of polysaccharides or glycosylations. This product is made of saccharides, which are carbohydrates that have been modified with glycosylation or polysaccharide modifications. NGA3F N-Glycan can be used in a variety of applications such as pharmaceuticals, food additives, and cosmetics.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Xylosyl-cellobiose is a monosaccharide that was synthesized and modified by methylation, click modification, and fluorination. The compound has been shown to be complex carbohydrate and an oligosaccharide with a polysaccharide. It is a high-purity substance that can be used for the synthesis of saccharides, carbohydrates, or sugars. CAS No. 129865-02-7

Cellulose derivative, food thickener and emulsifier, bulk forming laxative

Man-7D3 N-glycan is a high purity, custom synthesis, sugar, Click modification, fluorination, glycosylation and synthetic oligosaccharide. It has CAS No. and molecular weight of 538.9 Da. Man-7D3 N-glycan is an oligosaccharide with a monosaccharide and saccharide content of 100%. The sugar composition is 10% mannose, 10% galactose, 7% glucose and 3% fucose. This carbohydrate is a complex carbohydrate that contains both linear and branched structures.

Stability Hygroscopic Applications 3-HABA Kanamycin A is an impurity of Amikacin (A578500). References Gunawardana, G., et al.: J. Antibiot., 50, 887 (1997)

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

4-Aminophenyl 6-O-(a-D-mannopyranosyl)-a-D-mannopyranoside is a custom synthesized carbohydrate that belongs to the group of oligosaccharides. It is a saccharide with a mannose, glucose, and mannose backbone structure. This compound has been modified by methylation at the C4 position, glycosylation at the C3 position, and fluorination at the C6 position. The 4-aminophenyl 6-O-(a-D-mannopyranosyl)-a-D-mannopyranoside is available in high purity and can be used for research purposes.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Trifucosyl-p-lacto-N-hexaose is a complex carbohydrate that has been modified by methylation and glycosylation. It is a synthesized sugar that may be used as a pharmaceutical agent or as an additive in food products. Trifucosyl-p-lacto-N-hexaose has been modified using Click chemistry and fluorination, which have been shown to increase the purity of this compound. This product has a high degree of purity, as it is synthesized from pure materials.

The compound 4-Methoxyphenyl 4-O-(3,6-di-O-benzyl-2-deoxy-4-O-levulinoyl)-2,3,4,6-tetra-O-benzyl-a-L -fucopyranosyl)-2,3,4,6-tetra-O-benzyl-a-L -fucopyranoside is a glycoside of the monosaccharide 2,3,4,6 tetra O benzyl a L fucopyranose. It is prepared by the reaction of methyl 4 methoxyphenol with 2 deoxy 4 levulinoyl 2 phthalimido b D glucopyranoside in the presence of an acid catalyst. The compound has been shown to have anti inflammatory and anti allergic effects. The 6 Fluoro 3 Indoxyl Beta D Gal

Applications Lobetyolin is a natural phenolic glycoside found in herbal remedies used in Chinese and Korean medicine. Potential treatment for diabetic complications. References Jang, D. et al.: Arch. Pharm. Res., 33, 875 (2010); Koike, Y. et al.: J. Nat. Med., 64, 245 (2010);

Applications 2,4-Bis(acetylamino)-2,4,6-trideoxy-D-galactose is a glycopolymer located on the surface of cells that necessary in the immune response of a host. It influences biological functions and effect communication between different cells. References Schmoelzer, C. et al.: Carb. Res., 367, 1 (2013);

Anti-SARS-CoV/SARS-CoV-2 Spike Antibody-HRP (2J777) is a HRP-conjugated Chimera antibody targeting SARS-CoV/SARS-CoV-2 Spike. Anti-SARS-CoV/SARS-CoV-2 Spike Antibody-HRP (2J777) can be used in ELISA.

Applications Labeled D-Ribose, which is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate. References Ostrowski, S., et al.: Science, 305, 71 (2004), Vavilin, D., et al.: Biochim. Biophys. Acta, 1708, 91 (2005), Fletcher, J., et al.: Anal. Chem., 79, 2199 (2007), Weissleder, R., et al.: Nature, 452, 580 (2008),

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

2-Acetamido-2-deoxy-4-O-(6-sulfo-b-D-galactopyranosyl)-b-D-glucopyranose sodium salt (6F3G) is a synthetic, fluorinated monosaccharide that has been used as a probe for the study of glycosylation and polysaccharide synthesis. 6F3G has been shown to be an effective inhibitor of the enzyme D-glycerate kinase, which catalyzes the conversion of D-glycerate to phosphoenolpyruvate. This inhibition leads to a decrease in the formation of ATP and NADH, which provides evidence that 6F3G binds to the active site of this enzyme.

Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Applications (±)-2-Pentyl-1,1,1,3,3-d5 Alcohol (CAS# 14629-70-0) is a useful isotopically labeled research compound.

Applications Labelled Clarithromycin (C559750). Clarithromycin is a semi-synthetic macrolide antibiotic. Clarithromycin is a derivative of Erythromycin (E650000). References Benson, C., et al.: Eur. J. Clin. Microbiol., 6, 173 (1987), Boyanova, L., et al.: J. Med. Microb., 61, 85 (2012), Lin, Z., et al.: Toxicol. Sci., 126, 114 (2012),

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions.

Man-2a N-glycan is a modification of the oligosaccharide mannose that is an important component of many glycoproteins. This product can be custom synthesized, and has been shown to have high purity. It is a carbohydrate that contains a monosaccharide and a polysaccharide. The glycan may also contain methylation, glycosylation, or fluorination. It has CAS No. 491845-49-9, which is the number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society to identify substances.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

2,3,6,2',3',4',6'-Hepta-O-acetyl-b-maltosyl azide is a glycosylation agent that can be used in organic synthesis. It is a custom synthesis and can be modified to meet the customer's needs. This product has a CAS number of 33012-49-6 and has high purity with a saccharide content of >99%.

Applications Cyanidin 3-O-Rutinoside retards absorption of carbohydrates by inhibition of α-glucosidase which may be useful as a potential inhibitor for prevention and treatment of diabetes mellitus. References Raptis, S., et al.: Exp Clin Endocrinol Diabetes 2001, 109, S265,,Ceriello, A; Diabetes 2005, 54, 1,,Chiasson, J; Endocr Pract 2006, 12, 25,,,Misra, A; J Clin Endocrinol Metab 2008, 93, S9

4-Methoxyphenyl 4-O-[6-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-b-D-galacto 2 nonulopyranosylonate)-2,3 -di -O -benzyl b D galactopyranosyl]-2,3,6 -tri -O benzyl b D glucopyranoside is a modification of a sugar molecule. It is an oligosaccharide that belongs to the category of complex carbohydrates. The sugar is synthesized from monosaccharides and polysaccharides. The chemical name for the sugar is 4 methoxyphenyl 4 O-[6 O (methyl 5 acetamido 4 7 8 9 tetra O acetyl 3 5 dideoxy D glycero b D galacto 2 nonul

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Applications Isotope labelled L-Fucose (F836100), an hexose deoxy sugar that is claimed to have applications in cosmetics and pharmaceutical. References Hayes, M.L., et al.: J. Am. Chem. Soc., 104, 6764 (1982); Sato, K., et al.: Tetrahedron. Lett., 46, 237 (2005);

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Core antigen fragment in ABO blood group system

Applications A new potent neuraminidase (NA) inhibitor, shows long-acting anti-influenza virus activity. References Bantia, S., et al.: Antimicrob. Agents Chemother., 42, 801 (1998), Honda, T., et al.: Bioorg. Med. Chem. Lett., 12, 1925 (2002), Kiso, M., et al.: Lancet, 364, 759 (2004), Macdonald, S., et al.: J. Med. Chem., 48, 2964 (2005),

Glycyl-chitobiose is an oligosaccharide that can be synthesized from glycerol and chitobiose. This product is often used as a building block for the synthesis of complex carbohydrate molecules. The purity of Glycyl-chitobiose is greater than 98% and it has been modified with fluorine, methyl, and click chemistry. The CAS number for this product is 627-14-1.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

This mixture contains some of the penta- and hexasaccharides in human milk.

Stability Hygroscopic Applications N-Acetyl-D-mannosamine-d3 is the isotope labelled analog of N-Acetyl-D-mannosamine (A186199) which is a derivative of D-Mannosamine (M167000). References Pukanud, P. et al.: Drug Delivery, 16, 289 (2009)

β-(1→2)-Oligomannoside constituents of the Candida albicans cell wall have been shown to possess immunostimulatory properties, as evidenced by induction of cytokine production, including tumor necrosis factor (TNF) production, in humans and mice. In particular, oligosaccharide fractions, isolated and fractionated from the C. albicans cell wall, have been shown to induce TNF production in mouse macrophages. Therefore, biological studies employing well-defined synthetic β-(1→2)-linked oligomannoside compounds are of interest for verifying and studying in detail the proposed immunostimulatory properties of such constructs.

Anti-IL-10 Antibody (1L236) is a Rabbit antibody targeting IL-10. Anti-IL-10 Antibody (1L236) can be used in ELISA.

Anti-IL-10 Antibody (4I919) is a Mouse antibody targeting IL-10. Anti-IL-10 Antibody (4I919) can be used in ELISA.

Man-8 Glycan, 2-AB labelled is a carbohydrate, modification. It is a saccharide that has been fluorinated and modified with methylation and glycosylation. It has a CAS number of 7071-83-0, and is available for custom synthesis. This product has high purity, is synthetic, and can be modified with a click modification. The molecular weight of this product is 604.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human