Carbohydrates and glycoconjugates

Glycyl-lacto-N-neodifucohexaose I is a synthetic carbohydrate that has been modified to include a fluorine atom. Glycyl-lacto-N-neodifucohexaose I is an oligosaccharide that belongs to the class of carbohydrates and is composed of glycosylated and methylated monosaccharides. This product can be custom synthesized for your specific needs.

Stability Hygroscopic Applications Stachyose Hydrate is a low molecular weight carbohydrate that was separated through an EM Gel OR-PVA column. References Belue, G.P., McGinnis, G.D.: J. Chormatogr., 97, 25 (1974)

Lactose is the principal sugar in human and most other mammalian milks, ( 4-O-(β-d-galactopyranosyl)-d-glucopyranose) (Collins, 2006). Lactose undergoes mutarotation; it is a reducing sugar and is significantly less soluble in water than sucrose. Lactose is much less sweet than sucrose (at ~1% about 0.15 (sucrose=1). The enzyme lactase (β-galactosidase), which is present in the small intestine, catalyzes hydrolysis of lactose to form glucose and galactose. Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. Lactose also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods (Linko, 1982).

Lewis X is a glycoprotein found on the surface of red blood cells and is composed of a trisaccharide that is covalently attached to the protein. It is expressed in the cells of all individuals, but at different levels depending on their blood group. Lewis X is an antigen for monoclonal antibody, which recognizes it by binding to its sugar residues. The antibody can be used to detect Lewis X-expressing cells in the blood and for cancer diagnosis. Antibodies against Lewis X can also be used to inhibit tumor growth by enhancing natural killer cell activity and killing tumor cells.

Tetrasaccharide dp4 is a custom synthesis that is modified with fluorination, methylation, and click modification of the monosaccharides. It can be used for the synthesis of oligosaccharides and saccharides. Tetrasaccharide dp4 is a glycosylated carbohydrate that belongs to the group of polysaccharides. This product has CAS number 87392-00-6.

FA2B N-glycan also know as asialo, agalacto, core-fucosylated, bisected, bi-antennary N-linked glycan.

3'-Sialyllactose-APD-HSA is a complex carbohydrate with Oligosaccharide and Polysaccharide. It is a modification of saccharides, which are composed of monosaccharides or simple sugars. 3'-Sialyllactose-APD-HSA is a synthetic compound that has been modified by the addition of fluorine atoms to the sugar molecule. This modification prevents the sugar from being broken down by enzymes in the body and ensures that it remains intact until it reaches its target site. 3'-Sialyllactose-APD-HSA is used as a drug delivery system for cancer drugs, such as doxorubicin and paclitaxel.

Chondroitin disaccharide di-triS tetrasodium salt is a synthetic, custom synthesis, and a glycosylation of chondroitin disaccharide. It is an oligosaccharide that has been modified with fluorination, monosaccharide, methylation, and click modification. The CAS No. for this compound is

1.

linear a-(1,4) trisaccharide produced from starch by acid or enzyme hydrolysis

4-O-b-(2,3,4,6-Tetra-O-acetyl-D-galactopyranosyl)-1,6-anhydro-2,3-O-isopropylidene-b-D-mannopyranose is a custom synthesis of a monosaccharide. This monosaccharide is synthesized by the fluorination and methylation of 4,6 anhydro b D mannose followed by the click modification of the hydroxyl groups. The chemical name for this monosaccharide is 1,6 anhydro 2,3 O isopropylidene b D mannopyranose. It has a molecular weight of 390. The CAS number for this monosaccharide is 5346 69 0. 4,6 anhydro b D mannose is found in polysaccharides such as glycosaminoglycans

Hyaluronate biotin is a custom synthesis of 750kDa. It has been modified with fluorination, methylation and click modification. This product is a glycosylation of saccharide, which is a carbohydrate that can be found in many foods and is used as a sweetener. The saccharides are complex carbohydrates that consist of long chains of monosaccharides or simple sugars. Click modification is the process by which a small molecule, usually an azide group or nitrenium ion, reacts with an electron-deficient alkyne group to produce a new covalent bond without breaking either existing bond.

Applications An iridoid glycoside that exhibits protective effects against hepatic injury and other diabetic complications associated with abnormal metabolic states and inflammation caused by oxidative stress and advanced glycation endproduct formation. A potential anti-amnesic agent. References Yamabe, N. et al.: Eur. J. Pharmmacol., 648, 179 (2010); de Carman Recio, M. et al.: Planta Medica, 3, 232 (1994); Kwon, S. et al.: Eur. J. Pharmacol., 619, 44 (2009);

Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarohexaose is reported to have potential for novel cosmeceuticals.

Sialyl Lewis X Cholesterol is a synthetically modified sugar

3'3-a-L-Arabinofuranosyl-xylotetraose is a custom synthesis of an oligosaccharide. It is a polysaccharide that is modified by methylation, glycosylation and carbamoylation. This carbohydrate has been fluorinated at the 3'3 position. The monosaccharide composition of this molecule is erythrose, arabinose and xylose.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

GalNAcb(1-3)Gala(1-3)Galb(1-4)Glc-b-pNP is a synthetic glycoconjugate that is a glycosylated complex carbohydrate. It has been modified by Click chemistry and fluorination, and contains the monosaccharides galactose, galactosamine, glucose, and glucuronic acid. GalNAcb(1-3)Gala(1-3)Galb(1-4)Glc-b-pNP is used as a substrate for enzyme assays to study the activity of glycosyltransferases such as galactosyltransferase. This product can be used for research purposes in immunology, molecular biology, biochemistry and other fields.

Pinoresinol diglucopyranoside is a natural compound found in Chinese herb. It has been shown to have an anti-atherosclerotic effect, which may be due to the inhibition of nuclear factor kappa-light-chain-enhancer (NF-κB) and matrix metalloproteinase (MMP)-9. Pinoresinol diglucopyranoside also inhibits collagenase activity in vitro and reduces inflammation in vivo. The molecular mechanism of this compound may involve the toll-like receptor 4 (TLR4) pathway, which is responsible for immune responses to bacterial products. Pinoresinol diglucopyranoside has been shown to inhibit the transcription and polymerization of DNA by binding to DNA gyrase and topoisomerase IV, respectively.

Anti-TREM-1 Antibody-Biotin (9L702) is a Biotin-conjugated Mouse antibody targeting TREM-1. Anti-TREM-1 Antibody-Biotin (9L702) can be used in ELISA.

4-Methoxyphenyl 4-O-[4-O-(3,4,6-tri-O-acetyl-2,4,6-trimethylbenzoyl)-b-D-glucopyranosyl]-3,6-di-O-[α-(1→2)-bromoacetamido]-b-D-glucopyranoside is a complex carbohydrate which belongs to the group of glycosides. It was synthesized by modification of the natural bovine erythrocyte glycoglycerolipid (glycolipid) and monosaccharide (monoglyceride). The synthesis is based on a series of reactions that include methylation and fluorination. This compound has been shown to have high purity and can be made in custom synthesis.

Non-reducing sucrose analog containing glucose and fructose; prebiotic fibre

Heparin disaccharide I-A trisodium salt is an oligosaccharide that is a synthetic and modified form of heparin. It is used as a pharmaceutical agent to prevent coagulation, and in the treatment of thrombosis, deep vein thrombosis, pulmonary embolism, and other cardiovascular diseases. This product has been custom synthesized for the modification of sugar structures, fluorination, methylation, sugar modification and click chemistry.

Found in milk with immunoprotective effects against pathogens in newborns and aids development and maturation of the immune system and gut microbiota. Suppresses adhesion and infectivity of bacteria and viruses, such as influenza viruses, HIV-1 and rotaviruses. Inhibits binding of cholera toxin.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Gycosaminoglycan in many organs; joint lubricant and shock absorber

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

5-O-β-D-Glucopyranosyl-D-xylitol is a disaccharide that is synthesized for use in research.