Carbohydrates and glycoconjugates

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).

Neotame (HSDB 7965), a white dipeptide methyl ester, is a potent non-nutritive sweetener used in many foods.

2-Acetamido-4-O-{2-acetamido-4-O-[3-O-[2,4-di-O-(2-acetamido-2,6-dideoxyb -D-glucopyranosyl)-a,D -mannopyranosyl]-6-O-[2,6 -di(2 -acetamido)-b -D -glucopyranosyl]-b D mannopyranosyl]] b D mannopyranosyl} 2,6 dideoxy b D glucopyranosyl} 6 O-(a L fucopyranosyl)}

Pentasaccharide derived from chitin

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Hyaluronate Rhodamine (HR) is a high purity, custom synthesis sugar that has been modified with Click chemistry. HR is a complex carbohydrate that consists of saccharides and oligosaccharides. HR has been synthesized using glycosylation and methylation reactions. Hyaluronate Rhodamine's CAS number is 1059-14-5.

Gala1-3Galb1-4(6-deoxyGlcNAc)-HSA is a custom synthesis of a complex carbohydrate. It is an oligosaccharide with CAS No. and Polysaccharide that has been modified by Methylation, Glycosylation, and Click modification. Carbohydrate is one of the most important macronutrients for human health, as it provides energy and cell building blocks. Sugar (e.g., glucose) is the simplest form of carbohydrate, while saccharide refers to chains of sugar molecules. Gala1-3Galb1-4(6-deoxyGlcNAc)-HSA has been fluorinated and synthesized with high purity in order to be used as a drug delivery system. This drug can be used to treat various diseases such as diabetes mellitus type I or II, cancer, or HIV/AIDS.

Kojitriose is a disaccharide composed of two glucose molecules. It has been shown to have insulin-sensitizing effects in animals and humans. Kojitriose binds to the surface of Streptococcus faecalis and prevents the growth of this bacteria. Kojitriose also has an inhibitory effect on mesenteroides, which are a type of bacterium found in the human gut. This disaccharide is enzymatically hydrolyzed to produce hydrogen fluoride, which inhibits the growth of Streptococcus faecalis and mesenteroides. The enzyme trehalase is responsible for this hydrolysis reaction, while hydroxyl groups act as nucleophiles that react with chloride ions to form hydrogen fluoride.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

3-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is a custom synthesis. It is a modification of the natural product. This compound has been fluorinated, methylated and monosaccharide modified. 3-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is a synthetic compound that has been created by click chemistry. It contains an oligosaccharide and saccharide group. The CAS number for this compound is 5873087-81-8. 3-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is also glycosylated with sugar groups and has complex carbohydrate chains.

DL-glyceric acid is a compound that is excessively secreted in the urine of patients with D-glyceric aciduria.