
Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Products of "Ketones and derivatives"
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4'-(2-Chloro-4-fluorophenoxy)acetophenone
CAS:Purity:98%Color and Shape:SolidMolecular weight:264.679992675781252'-Hydroxy-5'-methyl-3'-nitroacetophenone
CAS:Purity:97.0%Color and Shape:Solid, NeedlesMolecular weight:195.1739959716797Acemetacin
CAS:Acemetacin (TVX 1322) is a carboxymethyl ester of indometacin.Formula:C21H18ClNO6Purity:99.26%Color and Shape:Light Yellow SolidMolecular weight:415.821-(4-Bromo-2,6-difluorophenyl)ethanone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:235.0279998779297rac-Naproxen Methyl Ester-13C,d3
CAS:Controlled ProductApplications rac-Naproxen Methyl Ester-13C,d3 is an Labelled Naproxen (N377525) intermediate, an anti-inflammatory, analgesic and antipyretic agent.Formula:CC14D3H13O3Color and Shape:NeatMolecular weight:248.297Flufenamic Acid-d4
CAS:Controlled ProductFormula:C14H6D4F3NO2Color and Shape:NeatMolecular weight:285.25Parecoxib Sodium
CAS:Controlled ProductApplications Anti-inflammatory, analgesic. References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Polascheck, N., et al.: Exper. Neurol., 224, 219 (2010), Gudbjornsson, B., et al.: Eur. J. Clin. Pharmacol., 66, 619 (2010),Formula:C19H17N2O4S·NaColor and Shape:WhiteMolecular weight:392.404-Isobutylbenzoic Acid
CAS:Applications 4-Isobutylbenzoic Acid is used in the studies for the identification of the degradation products and potential impurities in Ibuprofen. 4-Isobutylbenzoic Acid is also applied in the determination of related substances in dexibuprofen using HPLC. References Dondoni, A., et al.: Farmaco, Edizione Pratica, 41, 237 (1986); Xie, L., et al.: Zhongguo Yaoshi, 19, 1088 (2016)Formula:C11H14O2Color and Shape:NeatMolecular weight:178.232,4,5-Trimethylketoprofen ((2RS)-2-[3-(2,4,5-Trimethylbenzoyl)phenyl]propanoic Acid)
CAS:Carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids andtheir derivFormula:C19H20O3Color and Shape:White Off-White SolidMolecular weight:296.141244-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoic Acid
CAS:Formula:C17H12F3N3O4SFlunixin meglumine
CAS:Controlled ProductFormula:C14H11F3N2O2·C7H17NO5Color and Shape:NeatMolecular weight:491.461-{4-[(2-chloroprop-2-en-1-yl)oxy]phenyl}ethan-1-one
CAS:Purity:95%Molecular weight:210.660003662109381-[3-(Chloromethyl)-4-methoxyphenyl]ethanone
CAS:Purity:97.0%Color and Shape:Liquid, No data available.Molecular weight:198.64999389648438(E)-4-(6-Methoxynaphthalen-2-yl)but-3-en-2-one
CAS:Controlled ProductFormula:C15H14O2Color and Shape:NeatMolecular weight:226.27Flunixin meglumine 100 µg/mL in Acetonitrile
CAS:Formula:C14H11F3N2O2·C7H17NO5Color and Shape:Single SolutionMolecular weight:491.46Ref: 4Z-M-68113
Discontinued product(2RS)-2-(3-Benzoylphenyl)propanamide
CAS:Formula:C16H15NO2Color and Shape:NeatMolecular weight:253.30Ibuprofen Carboxylic Acid-d3 (Mixture of Diastereomers)
CAS:Controlled ProductApplications The major labelled metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes. References Bhuyan, K., et al.: Life Sci., 38, 1463 (1986), Blakytny, R., et al.: Biochem. J., 288, 303 (1992),Ganea, E., et al.: Eur. J. Biochem., 231, 181 (1995), Mitchell, J., et al.: Br. J. Pharmacol., 128, 1121 (1999),Formula:C13H13D3O4Color and Shape:NeatMolecular weight:239.28N-Phenyl-3-(trifluoromethyl)aniline
CAS:Controlled ProductFormula:C13H10F3NColor and Shape:NeatMolecular weight:237.223'-Chloroacetophenone
CAS:Purity:97.0%Color and Shape:Liquid, ClearMolecular weight:154.58999633789062(S)-Moramide D-Tartrate
CAS:Controlled ProductApplications (S)-Moramide or Dextromoramide is a controlled substance (opiate). Analgesic (narcotic). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Aoyama, T., et al.: J. Pharm. Sci., 79, 465 (1990); Decamp, W., et al.: J. Pharm. Biomed. Anal., 11, 1167 (1993);Formula:C25H32N2O2·C4H6O6Color and Shape:NeatMolecular weight:542.62N,N-Dimethyl-2-[5-[(methylsulfamoyl)methyl]-1H-indol-3-yl]ethanamine N-Oxide Maleate
Formula:C14H21N3O3S·C4H4O41-(2,4,6-Trihydroxyphenyl)ethanone
CAS:Purity:98.0%Color and Shape:Solid, Light yellow powderMolecular weight:168.1479949951172(2-methoxy-4-propionylphenoxy)acetic acid
CAS:Purity:95.0%Color and Shape:Solid, White powderMolecular weight:238.23899841308594Metamizole EP Impurity C
CAS:Formula:C12H15N3OColor and Shape:Pale Yellow SolidMolecular weight:217.274'-BROMO-3',5'-DIFLUOROACETOPHENONE
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:235.0279998779297(2RS)-3-(Dimethylamino)-2-methyl-1-phenylpropan-1-one Hydrochloride
CAS:Controlled ProductFormula:C12H17NO·ClHColor and Shape:NeatMolecular weight:227.73Apomorphine-13C-d3 HCl
CAS:Formula:C1613CH14D3NO2·HClColor and Shape:Off-White SolidMolecular weight:271.34 36.461-(3-Iodo-4-methoxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:276.0729980468753-Cysteinylacetaminophen Trifluoroacetic Acid Salt
CAS:Controlled ProductStability Hygroscopic Applications 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)Formula:C11H14N2O4S·C2HF3O2Color and Shape:Off-White To Dark GreyMolecular weight:384.333-O-(Codein-2-yl)morphine
Controlled ProductApplications 3-O-(Codein-2-yl)morphine is an impurity of Codeine (C634075), a weak narcotic analgesic. References Eddy, S., et al.: J. Pharmacol. Exp. Ther., 67, 127 (1939), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 10, 93 (1981).Formula:C35H38N2O6Color and Shape:NeatMolecular weight:582.69Acetaminophen-d3
CAS:Controlled ProductApplications Acetaminophen-d3 is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)Formula:C82H3H6NO2Color and Shape:WhiteMolecular weight:154.182-Chloro-4-fluoroacetophenone
CAS:Purity:98.0%Color and Shape:LiquidMolecular weight:172.58000183105473-ACETYL-4-HYDROXY-BENZOIC ACID
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:180.158996582031252'-Chloro-4',5'-difluoroacetophenone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:190.570007324218751-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone
CAS:Purity:95.0%Molecular weight:207.2729949951172