Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Products of "Ketones and derivatives"
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4-Fluoro-3-methylacetophenone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:152.16799926757812(S)-Ketoprofen Tromethamine Salt (Dexketoprofen Trometamol)
CAS:Formula:C16H14O3·C4H11NO3Color and Shape:White To Off-White SolidMolecular weight:254.29 121.142',3'-Difluoropropiophenone
CAS:Purity:97.0%Color and Shape:LiquidMolecular weight:170.158996582031251-(4-Chloro-3-methoxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:Liquid, OilMolecular weight:184.61999511718753'-Fluoro-5'-(trifluoromethyl)propiophenone
CAS:Purity:97.0%Color and Shape:LiquidMolecular weight:220.16700744628906Ref: 4Z-M-6881
Discontinued product(1R,2S)-Tapentadol Hydrochloride
CAS:Controlled ProductApplications (1R,2S)-Tapentadol is the (1R,2S)-isomer of Tapentadol (T007200, HCl); a novel, centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical and clinical models of pain relief. References Znaleziona, J., et al.: J. Pharmaceut. Biomed., 105, 10 (2015); Boxenbaum, H., et al.: J. Pharm. Sci., 2, 47 (1999); Boase, S., et al.: Br. J. Clin. Pharmacol., 54, 493 (2002); Armstrong, S., et al.: Psychosomatics, 44, 515 (2003); Bjornsson, T., et al.: Drug Metab. Dispos., 31, 815 ( 2003)Formula:C14H23NO·ClHColor and Shape:NeatMolecular weight:257.80(S)-3-(4-Acetylphenyl)-2-aminopropanoic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:207.229003906254-Fluoro-3-nitroacetophenone
CAS:Purity:98.0%Color and Shape:SolidMolecular weight:183.138000488281253'-Iodoacetophenone
CAS:Purity:98.0%Color and Shape:Solid, Low Melting SolidMolecular weight:246.04699707031254-Formylaminoantipyrine 100 µg/mL in Acetonitrile
CAS:Formula:C12H13N3O2Color and Shape:Single SolutionMolecular weight:231.25Quinicine Hemioxalate
CAS:Formula:C20H24N2O2·5C2H2O4Color and Shape:White To Off-White SolidMolecular weight:324.42 0.5*90.03Hydroxy Carisoprodol (mixture of diastereomers)
CAS:Controlled ProductApplications Hydroxy Carisoprodol is the metabolite of Carisoprodol (C183580) in equine urine and serum. References Kintz, P., et al.: J. Anal. Toxicol., 17, 408 (1993), Olsen, H., et al.: Ther. Drug Monit., 16, 337 (1994), Reeves, R., et al.: J. Addict. Diseas., 18, 51 (1999),Formula:C12H24N2O5Color and Shape:NeatMolecular weight:276.33Ketobemidone
CAS:Controlled ProductApplications An opioid analgesic. Used as a substitute to morphine for postoperative pain in children. References Lundeberg, S. et al.: Acta Anaesthesiol. Scand., 54, 435 (2010); Christensen, T. et al.: Neurosci. Res. Comm., 26, 77 (2000);Formula:C15H21NO2Color and Shape:Light BeigeMolecular weight:247.33Acetaminophen Dimer-d6
CAS:Controlled ProductApplications Acetaminophen Dimer-d6 is deuterium labeled Acetaminophen Dimer (A161235). Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3). References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)(3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)Formula:C16H10D6N2O4Color and Shape:NeatMolecular weight:306.35Ketoprofen Impurity 8 HCl
CAS:Formula:C20H23NO5·HClColor and Shape:White To Off-White SolidMolecular weight:357.41 36.461-(2-Hydroxyphenyl)ethanone (2-Hydroxyacetophenone)
CAS:Controlled ProductFormula:C8H8O2Color and Shape:NeatMolecular weight:136.15Salicylamide
CAS:Controlled ProductApplications Analgesic. References Simonsen, K., et al.: J. Anal. Toxicol., 34, 367 (2010), Komsta, L., et al.: J. Pharm. Biomed. Anal., 53, 911 (2010),Formula:C7H7NO2Color and Shape:Off-WhiteMolecular weight:137.141-(5-Hydroxy-2-nitrophenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:181.147003173828122'-Fluoroacetophenone
CAS:Purity:97.00%Color and Shape:Liquid, ClearMolecular weight:138.14100646972656rac-Moramide
CAS:Controlled ProductApplications The racemic Moramide. (S)-Moramide or Dextromoramide is a controlled substance (opiate). Analgesic (narcotic). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Aoyama, T., et al.: J. Pharm. Sci., 79, 465 (1990), Decamp, W., et al.: J. Pharm. Biomed. Anal., 11, 1167 (1993),Formula:C25H32N2O2Color and Shape:NeatMolecular weight:392.5018,19-Dehydrobuprenorphine
CAS:Controlled ProductApplications An analogue of Buprenorphine (B689570) which displays high affinity and selectivity for μ-opioid receptors. It acts as an antinociceptive agent and potent analgesic. References Lattanzi, R. et al.: Life. Sci., 70, 2177 (2002); Lattanzi, R. et al.: Brit. J. Pharmacol., 134, 441 (2001);Formula:C29H39NO4Color and Shape:NeatMolecular weight:465.62(4'-ACETYL-[1,1'-BIPHENYL]-4-YL)BORONIC ACID PINACOL ESTER
CAS:Purity:95.0%Molecular weight:322.20999145507812'-FLUORO-3'-NITROACETOPHENONE
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:183.13800048828125Felbinac Methyl Ester
CAS:Controlled ProductFormula:C15H14O2Color and Shape:NeatMolecular weight:226.27rac 2-(tert-Butyldimethylsilyloxy)-Alpha-desmethyl Ibuprofen-d6
CAS:Controlled ProductApplications 2-Hydroxy Ibuprofen-d6 (H942862) derivative.Formula:C18H24D6O3SiColor and Shape:NeatMolecular weight:328.55Capsaicin-d3 (E/Z-Mixture)
CAS:Controlled ProductApplications A representative lot is a 5:1 E:Z mixture.Labelled Capsaicin (C175680). Has been isolated from paprika and cayenne. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.Note this is a powerful irritant. One part in 100 000 can be tasted. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Molnar, et al.: Arzneim.-Forsch., 15, 718 (1965), Monsereenusorn,Y., et al.: Crit. Rev. Toxicol., 10, 321 (1982),Formula:C18D3H24NO3Color and Shape:NeatMolecular weight:308.432'-BROMO-3',4'-DIFLUOROACETOPHENONE
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:235.0279998779297
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