Steroids and Derivatives

M01449 - CHAPS, High Purity

Altrenogest (Allyltrenbolone)(A35957; RU2267), a progestogen, has structural relation with veterinary steroid trenbolone.

Atorvastatin methyl ester is a statin drug that inhibits the synthesis of cholesterol and other lipids in the body. It is used to reduce high levels of low-density lipoprotein (LDL) cholesterol, which may lead to heart disease or stroke. Atorvastatin methyl ester has been shown to be effective in reducing the uptake of LDL cholesterol into cells by preventing the formation of LDL particles. This drug also decreases the production of biphosphate-containing phospholipids, which are essential for dendritic cell maturation. The crystalline polymorphs have been characterized by X-ray diffraction and microscopy. Impurities can be detected using ultraviolet spectroscopy, infrared spectroscopy, or nuclear magnetic resonance spectroscopy.

Applications Progesterone 3-(O-carboxymethyl)oxime is used in microtitre plate enzyme immunoassays (EIAs) for progesterone.

Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue.

Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.

Ketones and quinones, w/not with other oxygen function,and their halogenated,sulfated,nitrated,or nitrosated derivatives, nesoi

Stability Light Sensitive Applications Isovitamin D3 is a metabolite of Vitamin D. Studies show that Isovitamin D3 is biologically active in normal rats but inactive in anephric rats. References Holick, M.F. et al.: Science, 180, 964 (1973); Wilczek, H. et al.: Prak. Lek., 59, 794 (1979);

Stigmasterol (Stigmasterin) is a phytosterol with a function in the maintenance of cell membranes. Stigmasterol lowers cholesterol levels. Cost-effective and quality-assured.

Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active.

Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.