Nucleosides and Nucleotides
Nucleosides are compounds formed by a nitrogenous base linked to a sugar (ribose or deoxyribose). When a phosphate group is added to the nucleoside, a nucleotide is formed. These compounds are essential in cellular biology, as nucleotides are the fundamental building blocks of DNA and RNA, responsible for storing and transmitting genetic information. Nucleosides have applications in the treatment of viral diseases, acting as inhibitors of viral replication. Nucleotides, besides their structural role in nucleic acids, are involved in energy processes, such as ATP synthesis.
At CymitQuimica, we offer a wide range of nucleosides and nucleotides essential for research in molecular biology, virology, and pharmacology.
Products of "Nucleosides and Nucleotides"
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Cladribine
CAS:Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Formula:C10H12ClN5O3Purity:100% - 99.99%Color and Shape:White Crystalline SolidMolecular weight:285.69Canagliflozin Impurity 18 (Mixture of Diastereomers)
CAS:Formula:C24H25FO6SColor and Shape:White To Off-White SolidMolecular weight:460.52Azacitidine USP Related Compound B
CAS:Controlled ProductFormula:C28H24O9Color and Shape:NeatMolecular weight:504.48Floxuridine
CAS:Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.Formula:C9H11FN2O5Purity:98.92% - 99.96%Color and Shape:SolidMolecular weight:246.19Azacitidine USP Related Compound C (Free Base)
CAS:Formula:C7H14N4O5Color and Shape:Off-White SolidMolecular weight:234.21Entecavir EP Impurity B HCl
CAS:Formula:C12H15N5O3·HClColor and Shape:White To Off-White SolidMolecular weight:277.29 36.461-(5-O-Benzoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide (5'-O-Benzoylribavirin)
CAS:Controlled ProductFormula:C15H16N4O6Color and Shape:NeatMolecular weight:348.31Dapagliflozin
CAS:Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Formula:C21H25ClO6Purity:99.5% - 99.74%Color and Shape:SolidMolecular weight:408.87Dextrose
CAS:Glucose (dextrose)Formula:C6H12O6Color and Shape:Colorless White Crystalline Powder GranularMolecular weight:180.2Entecavir Impurity 12
Formula:C32H33N5O4Color and Shape:White To Off-White SolidMolecular weight:551.65Chlorotrianisene
CAS:Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.Formula:C23H21ClO3Purity:98.88% - 99.03%Color and Shape:Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)Molecular weight:380.86Ref: TM-T2569
1mg59.00€5mg127.00€10mg205.00€25mg344.00€50mg512.00€100mg730.00€200mg998.00€1mL*10mM (DMSO)139.00€Ganciclovir Monoacetate
CAS:Formula:C11H15N5O5Color and Shape:White To Off-White SolidMolecular weight:297.27Cladribine Related Compound A (2-methoxy-2'-deoxyadenosine)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C11H15N5O4Color and Shape:White Off-White Crystalline PowderMolecular weight:281.1124Peramivir Impurity 28
CAS:Formula:C12H19NO4Color and Shape:White To Off-White SolidMolecular weight:241.29Emtricitabine Tenofovir Disoproxil Dimer
CAS:Formula:C28H40FN8O13PSColor and Shape:White To Off-White SolidMolecular weight:778.70Emtricitabine N,N’-Methylene Dimer
Controlled ProductApplications Emtricitabine N,N’-Methylene Dimer is a derivative compound of Emtricitabine (E525000), a reverse transcriptase inhibitor. It is effective antiviral agent against HIV, and other viruses replicating in a similiar manner. A nucleoside analog structurally related to Lamivudine (L172500). References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)Formula:C17H20F2N6O6S2Color and Shape:NeatMolecular weight:506.5(R)-Oxiracetam
CAS:(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam is a nootropic drug of the racetam family and stimulant.Formula:C6H10N2O3Color and Shape:SolidMolecular weight:158.16Adenosine 5'-diphosphate
CAS:Adenosine 5'-diphosphate (ADP) is a natural nucleotide derived from the dephosphorylation of ATP. ADP induces platelet aggregation. Cost effective and quality assured.Formula:C10H15N5O10P2Purity:100% - 99.81%Color and Shape:SolidMolecular weight:427.2LY450108
CAS:LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.Formula:C19H22F2N2O3SPurity:100% - 98.8%Color and Shape:SolidMolecular weight:396.45Ref: TM-TQ0289
2mg39.00€5mg58.00€10mg94.00€25mg145.00€50mg212.00€100mg295.00€200mg470.00€1mL*10mM (DMSO)65.00€AKR1C3-IN-9
AKR1C3-IN-9: Selective AKR1C3 inhibitor, IC50=8.92 nM; reverses DOX resistance in breast cancer.Formula:C20H20N2O4Purity:99.41%Color and Shape:SoildMolecular weight:352.38Ref: TM-T67846
5mg46.00€10mg64.00€25mg116.00€50mg187.00€100mg306.00€200mg442.00€1mL*10mM (DMSO)49.00€Ganciclovir triphosphate
CAS:Ganciclovir triphosphate: synthetic 2'-deoxy-guanosine analog, treats/prevents CMV, IC50 of 0.01 μM, effective across species.Formula:C9H16N5O13P3Color and Shape:SolidMolecular weight:495.17cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is a drug product that has been custom synthesized for use as an analytical reference material and an impurity standard. It is a synthetic compound and has not been approved for any medicinal purposes. The pharmacopoeia it falls under is the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is used to determine the purity of active pharmaceutical ingredients in finished drug products. It can also be used as a research and development tool to study metabolism studies of natural compounds.Formula:C8H9FN2O4SPurity:Min. 95%Molecular weight:248.23 g/molFolic acid
CAS:Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production new cells. Cost-effective and quality-assured.Formula:C19H19N7O6Purity:99.19% - 99.27%Color and Shape:Yellowish-Orange Crystals; Extremely Thin Platelets (Elongated @ 2 Ends) From Hot Water 482°FMolecular weight:441.4Uridine Impurity 2 (Pseudouridine)
CAS:Formula:C9H12N2O6Color and Shape:White To Off-White SolidMolecular weight:244.20RO 2433
CAS:Controlled ProductImpurity Sofosbuvir Metabolite GS331007 Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro. References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)Formula:C10H13FN2O5Color and Shape:NeatMolecular weight:260.22Uridine
CAS:Uridine (Uridin) is a nucleoside compound, a base that makes up RNA, that replaces thymine in DNA during transcriptione. Cost-effective and quality-assured.Formula:C9H12N2O6Purity:99.08% - 99.63%Color and Shape:White To Off-White Crystalline PowderMolecular weight:244.2Ref: 4Z-F-2432
Discontinued productUbidecarenone (Coenzyme Q10) EP Impurity B (Mixture of Isomers)
CAS:Formula:C44H66O4Color and Shape:Orange OilMolecular weight:659.01Thymidine (Zidovudine EP Impurity E, Zidovudine USP Related Compound D)
CAS:Formula:C10H14N2O5Molecular weight:242.23Gemcitabine EP Impurity C-13C-15N2
CAS:Formula:C813CH10F215N2O5Color and Shape:White To Off-White SolidMolecular weight:267.162-Aminopurine
CAS:2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.Formula:C5H5N5Purity:99.51%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:135.13ES 936
CAS:ES 936 is a potent and selective NQO1 inhibitor, inhibiting more than 95% of NQO1 100 nM, with a cell line-dependent inhibition duration.Formula:C18H16N2O6Purity:98%Color and Shape:SolidMolecular weight:356.33Dapagliflozin Propanediol
CAS:Formula:C21H25ClO6·C3H8O2Color and Shape:White To Off-White SolidMolecular weight:408.88 76.102-[2-(2-Amino-9H-purin-9-yl)ethyl]propane-1,3-diol Hydrochloride
CAS:Controlled ProductFormula:C10H15N5O2·ClHColor and Shape:NeatMolecular weight:273.721'-Epi gemcitabine, hydrochloride
CAS:Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.Formula:C9H12ClF2N3O4Purity:Min. 95%Molecular weight:299.66 g/molCytidine 5'-Monophosphate Disodium Salt
CAS:Formula:C9H12N3O8P·2NaColor and Shape:White To Off-White SolidMolecular weight:321.19 2*22.99Fludarabine
CAS:Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.Formula:C10H12FN5O4Purity:100% - 99.88%Color and Shape:White SolidMolecular weight:285.23Sofosbuvir Impurity 2
CAS:Formula:C31H27N3O8Color and Shape:White To Off-White SolidMolecular weight:569.58Sofosbuvir Impurity 40
CAS:Formula:C16H18FN2O8PColor and Shape:White To Off-White SolidMolecular weight:416.30Uridine-3’,5’-Cyclic Monophosphate Tetrabutylammonium Salt
CAS:Formula:C9H10N2O8P·C16H36NMolecular weight:305.16 242.47Cyclopropyl Diaminopurine Abacavir
CAS:Formula:C8H10N6Color and Shape:Off-White SolidMolecular weight:190.215’-O-[Bis(4-methoxyphenyl)phenylmethyl]-2’-deoxy-N-ethylcytidine
CAS:Formula:C32H35N3O6Molecular weight:557.652’-Deoxyadenosine
CAS:Applications 2prime-Deoxyadenosine is a nucleoside adenosine derivative with mutagenic properties.Formula:C10H13N5O3Color and Shape:White To Off-WhiteMolecular weight:251.2425-Fluorouracil
CAS:5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis.Formula:C4H3FN2O2Purity:100% - 99.98%Color and Shape:White To Practically White Crystalline Powder Neoplastic Drug Chemosterilant For Insects (Epa 1998)Molecular weight:130.08Peramivir Trihydrate
CAS:Peramivir Trihydrate (RWJ-270201) is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles areFormula:C15H28N4O4·3H2OPurity:99.52% - ≥95%Color and Shape:SolidMolecular weight:382.45Ref: TM-T2522
2mg47.00€5mg70.00€10mg103.00€25mg188.00€50mg311.00€100mg439.00€200mg635.00€500mg938.00€Ribavirin Impurity 33
CAS:Formula:C15H19N3O9Color and Shape:Pale Yellow LiquidMolecular weight:385.33Decarboxylated (S)-Adenosyl Methionine Tritrifluoromethanesulfonic Acid
CAS:Formula:C14H23N6O3S·CF3O3S·2CHF3O3SMolecular weight:355.44 149.06 2*150.07Emtricitabine 6’-Disulfide
CAS:Controlled ProductApplications An impurity of Emtricitabine synthesis.Formula:C16H18F2N6O4S4Color and Shape:NeatMolecular weight:524.6093’-Amino-3’-deoxythymidine
CAS:Controlled ProductImpurity Zidovudine Impurity; Stability Hygroscopic, Moisture Sensitive Applications A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT). References Qian, M., et al.: Biochem. Pharmacol., 48, 383 (1994), Diwan, B., et al.: Toxicol. Appl. Pharmacol., 161, 82 (1999) , Lim, S., et al.: J. Biol. Chem., 276, 23616 (2001), Von Tungeln, L., et al.: Carcinogenesis, 23, 1427 (2002),Formula:C10H15N3O4Color and Shape:White To Off-WhiteMolecular weight:241.24Ribavirin Impurity 39
CAS:Formula:C18H21N5O9Color and Shape:White To Off-White SolidMolecular weight:451.39Lamivudine EP Impurity I (Troxacitabine)
CAS:Formula:C8H11N3O4Color and Shape:White To Off-White SolidMolecular weight:213.199-[4-Acetoxy-3-(acetoxymethyl)butyl]-2-amino-6-chloropurine
CAS:Controlled ProductFormula:C14H18ClN5O4Color and Shape:NeatMolecular weight:355.78Dapagliflozin Impurity 55
CAS:Formula:C7H3BrCl2OColor and Shape:White To Off-White SolidMolecular weight:253.90Adefovir Dipivoxyl Impurity C
CAS:Formula:C16H26N5O6PColor and Shape:Off-White SolidMolecular weight:415.39Dapagliflozin hydroxy Impurity (Mixture of Diastereomers)
CAS:Applications (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol is an impurity of the drug Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor. References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)Formula:C21H25ClO7Color and Shape:White To Off-WhiteMolecular weight:424.872Acyclovir EP Impurity Q
Acyclovir EP Impurity Q is a drug product that is used as the impurity standard for Acyclovir EP. It is a natural metabolite of acyclovir and may be found in the urine of patients taking this drug. Acyclovir EP Impurity Q has shown to have antiviral activity against herpes simplex virus type 1 and type 2. The structure of this compound has been determined by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.Purity:Min. 95%
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