Nucleosides and Nucleotides
Nucleosides are compounds formed by a nitrogenous base linked to a sugar (ribose or deoxyribose). When a phosphate group is added to the nucleoside, a nucleotide is formed. These compounds are essential in cellular biology, as nucleotides are the fundamental building blocks of DNA and RNA, responsible for storing and transmitting genetic information. Nucleosides have applications in the treatment of viral diseases, acting as inhibitors of viral replication. Nucleotides, besides their structural role in nucleic acids, are involved in energy processes, such as ATP synthesis.
At CymitQuimica, we offer a wide range of nucleosides and nucleotides essential for research in molecular biology, virology, and pharmacology.
Products of "Nucleosides and Nucleotides"
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2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine
CAS:Controlled ProductImpurity Capecitabine 2-O-BDR Impurity (USP) Stability Hygroscopic Applications Capecitabine (C175650) impurity. Capecitabine 2-O-BDR Impurity (USP).Formula:C20H30FN3O9Color and Shape:NeatMolecular weight:475.47Azacitidine Impurity 10
CAS:Formula:C3H5N5OColor and Shape:White To Off-White SolidMolecular weight:127.11Valaciclovir Related Compound E
CAS:Valaciclovir Related Compound E is a white crystalline powder that has an appearance similar to acyclovir, with a melting point of 164-167°C. It is soluble in water and methanol. The compound is used as a medicament and also acts as an intermediate for the synthesis of other pharmaceutical products. Valaciclovir Related Compound E can be synthesized from valaciclovir by reacting it with ethyl chloroformate, followed by recrystallization from pyridine and chloroform. This process produces the desired product in high purity under good yield. Valaciclovir Related Compound E is a white crystalline powder that has an appearance similar to acyclovir, with a melting point of 164-167°C. It is soluble in water and methanol. The compound is used as a medicament and also acts as an intermediate for the synthesis of other pharmaceutical products. ValacFormula:C21H26N6O6Purity:Min. 95%Molecular weight:458.47 g/molRibavirin EP Impurity F
CAS:Formula:C10H14N4O6Color and Shape:White To Off-White SolidMolecular weight:286.24Emtricitabine Triphosphate Triethylammonium Salt
CAS:Controlled ProductStability Hygroscopic Applications Emtricitabine Triphosphate Triethylammonium Salt is a metabolite of (-)-Emtricitabine (E525000). References Barditch-Crovo, P., et al.: Antimicrob. Agents Chemother., 45, 2733 (2001); Ray, A., et al.: Antivir .Ther., 10, 451 (2005); Borroto-Esoda, K., et al.: Antivir. Ther., 11, 377 (2006)Formula:C8H13FN3O12P3S•3(C6H15N)Color and Shape:NeatMolecular weight:487.19101193Remdesivir impurity 7
CAS:Remdesivir is an antiviral drug. It is an RNA-dependent RNA polymerase inhibitor that has been shown to be effective against a broad range of RNA viruses, including influenza A and B, rhinovirus, respiratory syncytial virus, and parainfluenza virus. Remdesivir impurity 7 (impurity) is a byproduct of the synthesis process of remdesivir. It is a white crystalline solid with a strong chemical odor. This impurity can be synthesized in high purity as well as in custom specifications to meet the needs of pharmaceutical companies developing new drugs. The following are descriptions for 6-Fluoro-3-indoxyl-beta-D-galactopyranoside: Rifapentine is an anti-tuberculosis drug that belongs to the class of rifamycins. It inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription andFormula:C15H24NO5PPurity:Min. 95%Molecular weight:329.33 g/mol2’,3’-Di-O-acetyl-5’-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine
CAS:Controlled ProductFormula:C19H26FN3O8Color and Shape:WhiteMolecular weight:443.42Ribavirin Impurity 2
CAS:Formula:C13H18O9Color and Shape:White To Off-White SolidMolecular weight:318.28Lactose Monohydrate
CAS:Lactose in solid form and lactose syrup, nesoiFormula:C12H22O11·H2OColor and Shape:White Off-White Crystalline PowderMolecular weight:360.12678Fluorouracil-13C-15N2
CAS:Formula:C313CH3F15N2O2Color and Shape:Pale Yellow SolidMolecular weight:133.06Emtricitabine Impurity 18
CAS:Formula:C15H26O4SColor and Shape:White To Off-White SolidMolecular weight:302.43Remdesivir related compound 7
CAS:Remdesivir related compound 7 is a drug product that is being synthesized for use in research and development. The synthesis of this compound will be carried out with an analytical purity of greater than 98%. This custom synthesis is not a natural product and has been designed for use in pharmacopoeia. Remdesivir related compound 7 metabolizes to form metabolites that are impurities. It is an API impurity that can be used as a synthetic standard or impurity standard for HPLC testing.Formula:C15H17N5O4Purity:Min. 95%Molecular weight:331.33 g/mol(S,S)-Adenosyl-L-Methionine Di-1,4-Butanedisulfonate
Formula:C15H22N6O5S·2C4H10O6S2Molecular weight:398.44 2*218.24Melphalan Impurity 16 HCl
CAS:Formula:C13H18Cl2N2O3·HClColor and Shape:Off-White SolidMolecular weight:321.21 36.46Remdesivir Related Compound 4
CAS:Remdesivir Related Compound 4 is a synthetic compound that is structurally related to remdesivir. It has been shown to have anti-HIV activity in vitro. Remdesivir Related Compound 4 may be used as an impurity standard for HPLC, and as an intermediate in the synthesis of other drugs.Formula:C32H32N4O5Purity:Min. 95%Molecular weight:552.62 g/molZidovudine Impurity F
CAS:Formula:C10H14N2O5Color and Shape:White To Off-White SolidMolecular weight:242.23KL1333
CAS:KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts.Formula:C14H12N2O2Purity:98.79% - 99.27%Color and Shape:SolidMolecular weight:240.26Ref: TM-T16342
1mg94.00€5mg182.00€10mg274.00€25mg497.00€50mg747.00€100mg1,017.00€1mL*10mM (DMSO)240.00€Abacavir EP Impurity A
CAS:Formula:C14H18N6OColor and Shape:White To Off-White SolidMolecular weight:286.34Famciclovir-d4
CAS:Controlled ProductApplications A deuterated prodrug of Penciclovir (P221500), which is used as an antiviral. References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),Formula:C14H4H15N5O4Color and Shape:Off-White To Light BeigeMolecular weight:325.36Sofosbuvir Impurity 41 Triethylamine Salt
CAS:Formula:C16H25FN3O9P·Et3NMolecular weight:453.36 101.19CNQX disodium
CAS:CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.Formula:C9H2N4Na2O4Purity:97.77%Color and Shape:SolidMolecular weight:276.12Ref: TM-T8458
5mg47.00€10mg60.00€25mg119.00€50mg187.00€100mg298.00€200mg439.00€500mg715.00€1mL*10mM (DMSO)50.00€2'-Deoxy-2',2'-difluorouridine
CAS:Gemcitabine metaboliteFormula:C9H10F2N2O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:264.19 g/molrac-Melphalan EP Impurity A DiHCl (rac-Dihydroxy Melphalan DiHCl)
CAS:Color and Shape:Brown SolidMolecular weight:C13H20N2O4. 2 HClRemdesivir Impurity 34 (GS 441524)
CAS:Formula:C12H13N5O4Color and Shape:White To Off-White SolidMolecular weight:291.27S-Adenosyl-L-Methionine Disulfate p-Toluenesulfonate (Mixture of Diastereomers)
CAS:Formula:C15H22N6O5S·C7H8O3S·HO4S·H2O4SColor and Shape:White To Off-White SolidMolecular weight:399.45 172.20 97.06 98.07Decitabine Impurity 8 (Mixture of Diastereomers)
Formula:C8H12N4O4Color and Shape:White To Off-White SolidMolecular weight:228.21Decitabine Impurity 47
CAS:Formula:C7H14N4O4Color and Shape:White To Off-White SolidMolecular weight:218.21Capecitabine Impurity 8
Formula:C15H22FN3O6Color and Shape:White To Off-White SolidMolecular weight:359.35Valaciclovir EP Impurity D-d5 (Valacyclovir USP Related Compound D-d5)
Formula:C15H19D5N6O4Molecular weight:357.439-Carboxymethoxymethylguanine-13C2,15N
CAS:Stability Hygroscopic Applications 9-Carboxymethoxymethylguanine-13C2,15N is the labelled analog of 9-Carboxymethoxymethylguanine (C179990) which is a metabolite of Acyclovir (A192400-an antiviral, orally active acyclic nucleoside with inhibitory activity towards several herpes viruses). References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992); Gunness, P., et al.: Transl. Res., 158, 290 (2011);Formula:C2C6H915NN4O4Color and Shape:Light Beige SolidMolecular weight:242.167Dapagliflozin Impurity 109
CAS:Formula:C43H50Cl2O13Color and Shape:White To Off-White SolidMolecular weight:845.76Melphalan EP Impurity C DiHCl
CAS:Formula:C11H15ClN2O2·2HClColor and Shape:Brown SolidMolecular weight:242.70 2*36.46Sofosbuvir Impurity 15
Formula:C22H30N3O10PColor and Shape:White To Off-White SolidMolecular weight:527.47Vitamin B6 Impurity 6 HCl
Formula:C14H21NO3·HClColor and Shape:White To Off-White SolidMolecular weight:251.33 36.46NQO2-IN-1
CAS:NQO2-IN-1, a resveratrol analog, is a potent NQO2 inhibito,antitumor,generation of ROS and up-regulation of DR5 (death receptor 5) to promote apoptosis.Formula:C18H18N2O3Purity:99.83%Color and Shape:SoildMolecular weight:310.35Ref: TM-T203013
1mg201.00€5mg497.00€10mg701.00€25mg1,094.00€50mg1,508.00€100mg1,931.00€200mg2,637.00€CNQX
CAS:CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)Formula:C9H4N4O4Purity:99.70%Color and Shape:Pale Yellow SolidMolecular weight:232.15Ubidecarenone (Coenzyme Q10) Impurity 1
CAS:Formula:C64H98O4Color and Shape:Orange SolidMolecular weight:931.48Lamivudine Impurity 16 (α-Troxacitabine)
CAS:Formula:C8H11N3O4Color and Shape:White To Off-White SolidMolecular weight:213.19(S)-N-[4-[[((S)-2-Amino-6,7,8,9-tetrahydro-8-methyl-4,9-dioxo-4H-pyrazino[1,2-a]-1,3,5-triazin-7-yl)
Applications An impurity of Levomefolate (L375720), the natural form of folic acid. References Verlinde, P.H.C.., et al.: J. Agr. Food. Chem., 57, 6803 (2009); Whiteley, J.M., et al.: Biochem. Biophy. Res. Comm., 101, 1259 (1981);Formula:C20H23N7O7Color and Shape:NeatMolecular weight:473.44Lamivudine EP Impurity J
CAS:Formula:C8H10N2O4SColor and Shape:White To Off-White SolidMolecular weight:230.24Acyclovir (Aciclovir) EP Impurity L
CAS:Formula:C9H9N5O3Color and Shape:White To Off-White SolidMolecular weight:235.20Eritadenine
CAS:Controlled ProductApplications Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma. References Fukada, S., et al.: J. Nut., 136, 2797 (2006), Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006), Yamada, T., et al.: Biochem. Pharmacol., 73, 981 (2007), Enman, J., et al.; J. Agric. Food Chem., 56, 2609 (2008),Formula:C9H11N5O4Color and Shape:Off White SolidMolecular weight:253.212-Amino-9-β-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one (Guanosine)
CAS:Controlled ProductFormula:C10H13N5O5Color and Shape:NeatMolecular weight:283.24Capecitabine EP Impurity A (Capecitabine USP Related Compound A)
CAS:Formula:C9H12FN3O4Color and Shape:White To Off-White SolidMolecular weight:245.21Abacavir Sulfate
CAS:Formula:C14H18N6O·H2SO4Color and Shape:White To Off-White SolidMolecular weight:2*286.34 98.08Ribavirin Impurity 52
CAS:Formula:C7H7N5O3Color and Shape:White To Off-White SolidMolecular weight:209.17Cangrelor Impurity 9
Formula:C11H14F3N5OS2Color and Shape:White To Off-White SolidMolecular weight:353.38Canagliflozin
CAS:Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.Formula:C24H25FO5SPurity:100% - 99.76%Color and Shape:SolidMolecular weight:444.52Capecitabine
CAS:Controlled ProductApplications Capecitabine is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750). References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),Formula:C15H22FN3O6Color and Shape:White To Off-WhiteMolecular weight:359.35SCH442416
CAS:SCH442416: selective A2A adenosine receptor antagonist; Ki: 0.048 nM (human), 0.5 nM (rat).Formula:C20H19N7O2Purity:99.58%Color and Shape:SolidMolecular weight:389.41Ref: TM-T23336
1mg48.00€2mg63.00€5mg93.00€10mg139.00€25mg281.00€50mg449.00€100mg658.00€1mL*10mM (DMSO)97.00€Entecavir-13C2,15N
CAS:Controlled ProductApplications Labelled Entecavir. An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process. References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),Formula:C1013C2H15N415NO3Color and Shape:White To Off-WhiteMolecular weight:280.26Cytarabine Impurity 19
CAS:Formula:C9H13N3O5Color and Shape:White To Off-White SolidMolecular weight:243.22Pteroic acid, min95%
CAS:Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.Formula:C14H12N6O3Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:312.28 g/mol
![(S)-N-[4-[[((S)-2-Amino-6,7,8,9-tetrahydro-8-methyl-4,9-dioxo-4H-pyrazino[1,2-a]-1,3,5-triazin-7-y…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA629750.webp&w=3840&q=75)
