Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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5-Aminosalicylic Acid
CAS:Formula:C7H7NO3Purity:>98.0%(T)Color and Shape:White to Gray to Brown powder to crystalMolecular weight:153.14N-Desmethyl Apalutamide
CAS:Formula:C20H13F4N5O2SColor and Shape:White To Off-White SolidMolecular weight:463.414-((4,5-bis(hydroxymethyl)-2-methylpyridin-3-yl)oxy)-4-oxobutanoic acid hydrochloride
Formula:C12H15NO6HClMolecular weight:269.25 : 36.517-Hydroxy-3,11-dioxo-androsta-1,4-diene-17beta-carboxylic Acid
CAS:Controlled ProductApplications 17-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid is an intermediate used to prepare (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-androsta-1,4-diene-17-carboxylic acid (E890570) which is a derivative of Loteprednol Etabonate (L471400), an ophthalmic corticosteroid. References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)Formula:C20H24O5Color and Shape:NeatMolecular weight:344.40R-(-)-Methamphetamine-d3 Hydrochloride
CAS:Controlled ProductApplications A CNS stimulant. Anorexic. In attention deficit disorder with hyperactivity. Controlled substance (stimulant). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lands, M., et al.: J. Pharmacol. Exp. Ther., 89, 382 (1947), Repke, D.B., et al.: J. Pharm. Sci., 67, 1167 (1978), Pope, H.G., et al.: J. Clin. Psychiatry, 47, 339 (1986), Cho, A.K., et al.: Science, 249, 631 (1990),Formula:C10H13D3ClNColor and Shape:NeatMolecular weight:188.71DL-Homocysteic Acid
CAS:Formula:C4H9NO5SPurity:>97.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:183.18UDP-D-Galactose-13C6 Disodium Salt (Mixture)
Formula:C913C6H22N2O17P2·2NaMolecular weight:570.24 2*22.993-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-
CAS:Formula:C17H26O4Purity:98%Color and Shape:SolidMolecular weight:294.3859Vonoprazan Impurity 38
CAS:Formula:C17H16FN3O3SColor and Shape:White To Off-White SolidMolecular weight:361.391H-Benzimidazole-4-methyl-2-propyl-6-carboxylic Acid
CAS:Controlled ProductFormula:C12H14N2O2Color and Shape:NeatMolecular weight:218.25Dipyridamole Tri(diethanolamine)
CAS:Controlled ProductImpurity Dipyridamole EP Impurity B Applications Dipyridamole Tri(diethanolamine) (Dipyridamole EP Impurity B) Dipyridamole (D492625) impurity. References Gerlach, E., et al.: Arzneim.-Forsch., 15, 558 (1965),Formula:C23H40N8O6Color and Shape:NeatMolecular weight:524.61Ref: ST-EA-CP-N24008
Discontinued productN-Nitrosoephedrine
CAS:Controlled ProductFormula:C10H14N2O2Color and Shape:Light YellowMolecular weight:194.23Demethylamino Ranitidine Acetamide Sodium
CAS:Controlled ProductApplications Demethylamino Ranitidine Acetamide Sodium is a Ranitidine (R120000) impurity. A degradation product of Ranitidine hydrochloride. References Haywood, Phillip A., et al.: Org. Bio-Organic Chem., 5, 951 (1987),Formula:C12H18N3O4S·NaColor and Shape:NeatMolecular weight:323.34Xylene
CAS:Stability Volatile Applications Xylene, is the precursor for Terephthalic Acid and Dimethyl Terephthalate, both monomers used in the production of polyethylene terephthalate (PET) plastic bottles and polyester clothing. It can also be used as a solvent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Tremblay, J. F., et al.: Chem. Eng. News, 89 (38), 18 (2011); Clark, J. E., et al.: Ind. End. Chem., 47 (2), 250 (1955);Formula:C8H10Color and Shape:ColourlessMolecular weight:106.16Bendamustine Related Compound I (Ethyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoate)
CAS:Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFormula:C18H25Cl2N3O2Color and Shape:White SolidMolecular weight:385.132381,3,5-Tri(anthracen-9-yl)benzene (contains ~20% inorganics)
CAS:Controlled ProductFormula:C48H30Color and Shape:NeatMolecular weight:606.75N-Acetylamphetamine
CAS:Controlled ProductFormula:C11H15NOColor and Shape:White To Off-WhiteMolecular weight:177.207-APB Hydrochloride
CAS:Controlled ProductStability Hygroscopic Applications 7-APB (Hydrochloride) is a derivative of designer drugh 6-APB. It is a stimulant of phenethlamine and amphetamine classes. 7-APB (Hydrochloride) is used for forensic and research applications. References Stanczuk, A., et al.: Drug Test Anal., 5, 270 (2013)Formula:C11H13NO·HClColor and Shape:NeatMolecular weight:211.70Bimatoprost Impurity 23
Formula:C14H26N2O2Color and Shape:White To Off-White SolidMolecular weight:254.37Sodium Hippurate
CAS:Formula:C9H8NNaO3Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:201.16Argatroban Impurity 33
Formula:C11H11NO3SColor and Shape:White To Off-White SolidMolecular weight:237.27Goserelin-d7 Tritrifluoroacetate
CAS:Formula:C59H77D7N18O14·3C2HF3O2Color and Shape:White To Off-White SolidMolecular weight:1276.48 3*114.02Procarbazine Hydrochloride
CAS:Formula:C12H19N3O·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:257.768-Desmethoxy-8-fluoro Moxifloxacin
CAS:Impurity Moxifloaxacin EP Impurity A Stability Hygroscopic Applications 8-Desmethoxy-8-fluoro Moxifloxacin (Moxifloaxacin EP Impurity A) is an impurity of Moxifloxacin (M745000). References Martel, A., et al.: Drugs Fut., 22, 109 (1997), Tobin, C., et al.: J. Antimicrob. Chemother., 42, 278 (1998),Formula:C20H21F2N3O3Color and Shape:NeatMolecular weight:389.403,5-Diiodo-L-thyronine
CAS:Formula:C15H13I2NO4Purity:95%Color and Shape:SolidMolecular weight:525.076962,4-Diamino-6-piperidinopyrimidine (Desoxyminoxidil)
CAS:Impurity Minoxidil EP Impurity E Applications 2,4-Diamino-6-piperidinopyrimidine (Desoxyminoxidil) (Minoxidil EP Impurity E) is an analogue of Minoxidil (M345000). References Cox, J., et al.: Adv. Drug Res., 5, 115 (1970), Watanabe., et al.: Microbiol. Immunol., 23, 1009 (1979), Nakai, H., et al.: J. Med. Chem., 31, 84 (1988), Shiraishi, M., et al.: J. Med. Chem., 32, 2214 (1989),Formula:C9H15N5Color and Shape:Off-White To BeigeMolecular weight:193.25Tetrandrine
CAS:Formula:C38H42N2O6Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:622.76tert-Butyl 4-(Piperidin-4-ylmethyl)piperazine-1-carboxylate
CAS:Formula:C15H29N3O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:283.42Meloxicam-13C-d3
CAS:Formula:C1313CH10D3N3O4S2Color and Shape:Pale Yellow SolidMolecular weight:355.41Chloramphenicol 2-(O-tert-Butyldimethylsilyl)methyl 1-Acetate
CAS:Controlled ProductApplications Used in the preparation of Azithromycin (A927000) compounds as antibacterial, anti-proliferative, and antiinflammatory agents.Formula:C19H28Cl2N2O6SiColor and Shape:NeatMolecular weight:479.43Theophylline Hydrochloride Monohydrate
CAS:Formula:C7H8N4O2HClH2OMolecular weight:180.17 : 36.46 : 18.02[2-(3-Bromophenyl)-1-Hydroxy-1-Phosphono-Ethyl]phosphonic Acid
CAS:Formula:C8H11BrO7P2Molecular weight:361.02Oxandrolone Related Compound C CIII (17,17-dimethyl-18-nor-2-oxa-5α-androst-13-en-3-one)
Controlled ProductLactones nesoiFormula:C19H28O2Color and Shape:PowderMolecular weight:288.42Ethyl 4-Aminobutyrate Hydrochloride
CAS:Formula:C6H13NO2·HClPurity:>98.0%(T)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:167.63α-Hederin
CAS:Formula:C41H66O12Purity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:750.97Ubenimex
CAS:Formula:C16H24N2O4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:308.384-N-Desacetyl-5-N-acetyl Oseltamivir
CAS:Impurity Oseltamivir EP Impurity G (HCl Salt) Applications 4-N-Desacetyl-5-N-acetyl Oseltamivir (Oseltamivir EP Impurity G (HCl Salt)) is an impurity of the antiviral drug Oseltamivir (O701000). It is a COVID19-related research product. References Albert, K. et al.: Pharmazie, 62, 678 (2007);Formula:C16H28N2O4Color and Shape:White To Light BeigeMolecular weight:312.40Hydromorphone N-Oxide Hydrochloride CII (4,5α-Epoxy-3-hydroxy-17-methylmorphinan-6-one N-oxide, hydrochloride)
CAS:Controlled ProductAlkaloids of opium and their derivatives, salts thereofFormula:C17H19NO4·HClColor and Shape:Off-White PowderMolecular weight:337.79Diethanolamine Fusidate
CAS:Formula:C31H48O6·C4H11NO2Color and Shape:White To Off-White SolidMolecular weight:516.72 105.14Eltrombopag
CAS:Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the plateletFormula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.47N-Benzyloxycarbonyl-D-phenylalanine
CAS:Formula:C17H17NO4Purity:>98.0%(T)Color and Shape:White powder to crystalMolecular weight:299.33Methyl 3-Aminobenzoate
CAS:Formula:C8H9NO2Purity:>98.0%(GC)(T)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:151.173-Dimethylaminopropyl-2-benzylaminobenzoate Hydrochloride
CAS:Formula:C19H24N2O2·ClHColor and Shape:NeatMolecular weight:348.871-Ethynyl-3,5-bis(trifluoromethyl)benzene
CAS:Formula:C10H4F6Purity:>98.0%(GC)Color and Shape:Colorless to Light yellow to Light orange clear liquidMolecular weight:238.13(2S,4R,5S)-Lopinavir
CAS:Controlled ProductFormula:C37H48N4O5Color and Shape:NeatMolecular weight:628.802-(p-Tolyl)propionic Acid
CAS:Controlled ProductImpurity Ibuprofen EP Impurity D Applications 2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D. References Jia, C., et al.: Science, 287, 1992 (2000), Yu, J., et al.: Org. Biomol. Chem., 4, 4041 (2006),Formula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.20Acetic acid, copper(2+) salt, monohydrate
CAS:Formula:C4H8CuO5Purity:97%Color and Shape:SolidMolecular weight:199.6493Flurbiprofen (1S,2R,5S)-(+)-Menthyl Ester
Controlled ProductApplications Flurbiprofen (1S,2R,5S)-(+)-Menthyl Ester is an isomer version of Flurbiprofen rac-Menthyl Ester (M221723), a Flurbiprofen (F598700) derivative. Flurbiprofen is an anti-inflammatory used as an analgesic References Chalmers, et al.: Ann. Rheum. Dis., 31, 319 (1972), Nishizawa, et al.: Thromb. Res., 3, 577 (1973)Formula:C25H31FO2Color and Shape:NeatMolecular weight:382.5114-Hydroxy duloxetine glucuronide
Formula:C24H27NO8SColor and Shape:Pale Yellow SolidMolecular weight:489.553-Ethyl 5-Methyl 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate Fumarate
CAS:Formula:C20H23ClN2O5·C4H4O410,11-Dihydro Carbamazepine
CAS:Controlled ProductFormula:C15H14N2OColor and Shape:WhiteMolecular weight:238.282-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
CAS:Formula:C27H22Cl2N4Purity:98%Color and Shape:SolidMolecular weight:473.3964Ramelteon Metabolite M-II-d3 (mixture of R and S at the hydroxy position)
CAS:Controlled ProductApplications The major metabolite of Ramelteon in serum (M-II). References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004), Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004), Kato, K., et al.: Neuropharmacology, 48, 301 (2005), Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006),Formula:C16D3H18NO3Color and Shape:NeatMolecular weight:278.36
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