Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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5-Hydroxy Dantrolene
CAS:Controlled ProductFormula:C14H10N4O6Color and Shape:YellowMolecular weight:330.25Piperaquine Tetraphosphate Tetrahydrate
CAS:Formula:C29H32Cl2N6·4H3PO4·4H2OPurity:>98.0%(HPLC)(N)Color and Shape:White to Orange to Green powder to crystalMolecular weight:999.55N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-L-tyrosine
CAS:Formula:C25H23NO5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:417.46DL-Ornithine HCl
CAS:Formula:C5H13ClN2O2Purity:97%Color and Shape:SolidMolecular weight:168.62192000000002(R)-Warfarin-d5
CAS:Formula:C19H11D5O4Color and Shape:White To Off-White SolidMolecular weight:313.364-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-aspartate
CAS:Formula:C23H25NO6Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalineMolecular weight:411.45(R)-Hydroxychloroquine Sulfate
CAS:Formula:C18H26ClN3O·H2O4SColor and Shape:White To Ff-White SolidMolecular weight:335.88 98.07D-Asparagine Monohydrate
CAS:Formula:C4H8N2O3·H2OPurity:>99.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:150.146Alpha-Hydroxy-17Beta-estradiol 17-Valerate
CAS:Applications A potential impurity of Estradiol 17-Valerate (E888860).Formula:C23H32O4Color and Shape:NeatMolecular weight:372.5Valganciclovir Impurity 8 (Mixture of Isomers)
Formula:C14H22N6O5(HCl)Molecular weight:354.37 : 2(36.46)10’-Hydroxy-2,2’ bis-methylnaltrexone TFA Salt (>85%)
CAS:Controlled ProductApplications 10’-Hydroxy-2,2’ bis-methylnaltrexone is an impurity of Naltrexone Methobromide (M265395), an intermediate in the synthesis of derivatives of Naltrexone (N285745), an opioid antagonist used in flavour avoidance studies. References PCT Int. Appl. (2012), WO 2012010106 A1 20120126.Formula:C42H50N2O9·xC2HF3O2Purity:>85%Color and Shape:Light BrownMolecular weight:726.85 + x(114.02)Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, hydrochloride (1:1)
CAS:Formula:C10H16ClN3O5Purity:98%Color and Shape:SolidMolecular weight:293.7041Enrofloxacin Ethyl Ester
CAS:Formula:C21H26FN3O3Color and Shape:White To Off-White SolidMolecular weight:387.46Enramycin (Mixture of Enduracidin A and Enduracidin B)
CAS:Formula:C107H138Cl2N26O31C108H140Cl2N26O31Color and Shape:Off-White SolidMolecular weight:2355.33; 2369.365-[(2R)-2-[Bis[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide Hydrochloride
CAS:Formula:C30H40N2O7S·ClHEthylene Terephthalate Cyclic Pentamer-d20
CAS:Controlled ProductFormula:C50D20H20O20Color and Shape:White To Off-WhiteMolecular weight:980.96Paclitaxel
CAS:Formula:C47H51NO14Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:853.92Flurazepam Related Compound F (7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one)
CAS:Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoiFormula:C15H10ClFN2OColor and Shape:White PowderMolecular weight:288.046572-Ethoxy-4-[2-oxo-2-[[2-phenyl-1-[2-(1-piperidinyl)phenyl]ethyl]amino]ethyl]benzoic acid
CAS:2-Ethoxy-4-[2-oxo-2-[[2-phenyl-1-[2-(1-piperidinyl)phenyl]ethyl]amino]ethyl]benzoic acid is a drug product that has not yet been approved for use in humans. It is currently undergoing research and development to determine its safety, efficacy, and optimal dosage range. 2EtOBA has shown pharmacological activity in animal models of inflammation and pain. 2EtOBA is metabolized by esterases, glutathione reductase, cytochrome P450 enzymes, reduction by glutathione reductase or conjugation with glucuronic acid. The metabolite of 2EtOBA is the parent compound with a different side chain. This impurity standard can be used in HPLC methods to measure the concentration of this metabolite.Formula:C30H34N2O4Purity:Min. 95%Molecular weight:486.6 g/molIsoprenaline (Isoproterenol) HCl
CAS:Formula:C11H17NO3·HClColor and Shape:White To Off-White SolidMolecular weight:211.26 36.461-(3-(2-(Dimethylamino)ethyl)-1-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide Formate Salt
CAS:Controlled ProductFormula:C25H33N5O4S2·CH2O2Color and Shape:NeatMolecular weight:531.694603Sulfo-EMCS
CAS:Formula:C14H15N2NaO9SPurity:>95.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:410.336H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-
CAS:Formula:C21H25NO4Purity:97%Color and Shape:SolidMolecular weight:355.42756-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
CAS:Formula:C14H15N2NaO9SPurity:98%Color and Shape:SolidMolecular weight:410.33173-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt
CAS:Controlled ProductApplications A metabolite of Baclofen (c). References Ault, B., et al.: Eur. J. Pharmacol., 71, 357 (1981),Formula:C10H10ClNaO3Color and Shape:NeatMolecular weight:236.632-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-onehydrochloride
CAS:Formula:C13H19Cl2NOPurity:98%Color and Shape:SolidMolecular weight:276.2021Ref: IN-DA007IRL
Discontinued productPrasugrel-d4
CAS:Formula:C20H16D4FNO3SColor and Shape:White To Off-White SolidMolecular weight:377.47Dosulepin Sulfoxide N-Oxide Hydrochloride (Dosulepin N,S-Dioxide Hydrochloride)
Formula:C19H21NO2S·ClHRef: 4Z-C-2748
Discontinued productRivaroxaban Impurity 70
CAS:Formula:C5H2Cl2O2SColor and Shape:White To Off-White SolidMolecular weight:197.03Methyl Cellulose (13-18mPa·s, 2% in Water at 20°C)
CAS:Color and Shape:White to Almost white powder to crystalRemifentanil Diester Hydrochloride
Controlled ProductFormula:C17H24N2O4·HClColor and Shape:NeatMolecular weight:527.566Triisopropyl Phosphate
CAS:Controlled ProductApplications Triisopropyl Phosphate can be used as a flame retardant and catalyst. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Zhang, Tie-jiang.: Meitan Jishu,29(2), 204-206 (2010);Chen, Yong-Fu, et al.: Jingxi Huagong, 17(9), 541-543 (2000)Formula:C9H21O4PColor and Shape:NeatMolecular weight:224.23Temozolomide Related Compound A (4-diazo-4H-imidazole-5-carboxamide)
CAS:Compounds containing an unfused imidazole ring (whetherFormula:C4H3N5OColor and Shape:PowderMolecular weight:137.03376Desthiophenerivaroxaban Methylcarbamate Analog (methyl ((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)carbamate)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C16H19N3O6Color and Shape:White Off-White SolidMolecular weight:349.12739Mitoxantrone
CAS:Formula:C22H28N4O6Purity:>95.0%(HPLC)Color and Shape:Light orange to Dark red to Black powder to crystalMolecular weight:444.49Ref: 4Z-P-089
Discontinued productFmoc-Val-Cit-PAB-PNP
CAS:Formula:C40H42N6O10Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:766.81N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide
CAS:Controlled ProductImpurity Ranolazine USP Related Compound D Applications N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide is an intermediate of Ranolazine (R122500), an anti-ischemic agent which modulates myocardial metabolism. Ranolazine is also known to exert antianginal activities. References Sampath, A., et al.: Org. Proc. Rsch. Dev., 16, 748 (2012); Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004); McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998); Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002)Formula:C24H32N4O2Color and Shape:NeatMolecular weight:408.54Citalopram HBr
CAS:Formula:C20H21FN2O·HBrColor and Shape:White To Off-White SolidMolecular weight:324.40 80.914-Bromo-2,6-diethynylpyridine
CAS:Formula:C9H4BrNPurity:min. 98.0 %(GC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:206.04(11Beta,16Alpha)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:Controlled ProductStability Moisture Sensitive Applications (11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)Formula:C26H33BrO8Color and Shape:NeatMolecular weight:553.44Fluocortolone Pivalate
CAS:Formula:C27H37FO5Color and Shape:White To Off-White SolidMolecular weight:460.59N-Desethyl N-Methyl Rivastigmine
CAS:Controlled ProductImpurity Rivastigmine EP Impurity B Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic. References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),Formula:C13H20N2O2Color and Shape:NeatMolecular weight:236.32Benzenesulfonamide, 4-amino-N-(6-methoxy-3-pyridazinyl)-
CAS:Formula:C11H12N4O3SPurity:98%Color and Shape:SolidMolecular weight:280.30298Diethyl 2-Amino-2-(4-Octylphenethyl)malonate
CAS:Controlled ProductFormula:C23H37NO4Color and Shape:NeatMolecular weight:391.5442-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-, sulfate (2:1)
CAS:Formula:C28H38N12O6SPurity:98%Color and Shape:SolidMolecular weight:670.7431N-Nitroso Nebivolol
CAS:Formula:C22H24F2N2O5Color and Shape:White To Off-White SolidMolecular weight:434.44Tazarotene Sulfoxide
CAS:Applications Tazarotene Sulfoxide is a derivative of Tazarotene (T010050), used for treating skin disorders.Formula:C21H21NO3SColor and Shape:NeatMolecular weight:367.46Propargylamine hydrochloride
CAS:Formula:C3H6ClNPurity:95%Color and Shape:SolidMolecular weight:91.53944Uridine, 5'-deoxy-5-fluoro-
CAS:Formula:C9H11FN2O5Purity:98%Color and Shape:SolidMolecular weight:246.19244319999999T-705RTP Sodium Salt (>75%)
CAS:Applications 6-Fluoro-3,4-dihydro-4-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-oxo-pyrazinecarboxamide Sodium Salt was used in the preparation of novel pyrazine derivatives as antiviral agents. It is a salt analog of T-705RTP (T003210). References Egawa, H., et al.: PCT Int. Appl. (2001), WO 2001060834 A1 20010823; Egawa, H., et al.: Jpn. Kokai Tokkyo Koho (2004), JP 2004043371 A 20040212Formula:C10H15FN3O15P3·xNaPurity:>75%Color and Shape:Beige To Light YellowMolecular weight:529.16 + x(22.99)Tris[2-[[2,4,8,10-tetra-tert-butyldibenzo[d,f][1,3,2]dioxaphosphepin-6-yl]oxy]ethyl]amine
CAS:Formula:C90H132NO9P3Molecular weight:1464.974-tert-Butyl-2,6-dimethyl-3-hydroxyphenylacetic Acid
CAS:Controlled ProductImpurity Oxymetazoline EP Impurity D Applications 4-tert-Butyl-2,6-dimethyl-3-hydroxyphenylacetic Acid (Oxymetazoline EP Impurity D) is an impurity of Oxymetazoline (O876470), a vasoconstrictor used as a nasal decongestant. References Huang, X., et al.: Mol. Pharmacol., 76, 710 (2009); Kurko, D., et al.: Neurochem. Int., 55, 467 (2009)Formula:C14H20O3Color and Shape:White To Light YellowMolecular weight:236.31Budesonide-d8 (Mixture of Diastereomers)
CAS:Formula:C25H26D8O6Color and Shape:White To Off-White SolidMolecular weight:438.59Thiophene-2-carbothioamide
CAS:Formula:C5H5NS2Purity:>98.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:143.22(2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine
CAS:Formula:C10H13FN2O5Purity:97%Color and Shape:SolidMolecular weight:260.219
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