Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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Tirofiban Impurity 49
CAS:Formula:C14H21NO5SColor and Shape:White To Off-White SolidMolecular weight:315.38Clavulanate Lithium
CAS:Formula:C8H8NO5·LiColor and Shape:White To Off-White SolidMolecular weight:198.16 6.94Albuterol 4-O-Sulfate
CAS:Formula:C13H21NO6SColor and Shape:White To Off-White SolidMolecular weight:319.37Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1α,6β,7α,14R)-
CAS:Formula:C20H28O6Purity:98%Color and Shape:SolidMolecular weight:364.4327Demethyl Chlorpromazine Hydrochloride
CAS:Controlled ProductImpurity Chlorpromazine EP Impurity D Applications A metabolite of Chlorpromazine (C424750). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Neuhoff, E., et al.: Archiv. der Pharmazie, 288, 400 (1955), Tomita, M., et al.: Chem. Pharm. Bull., 16, 688 (1968),Formula:C16H17ClN2S·ClHColor and Shape:WhiteMolecular weight:341.30(R)-Oxybutynin Chloride
CAS:Controlled ProductApplications The optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)Formula:C22H31NO3·ClHColor and Shape:NeatMolecular weight:393.951H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-
CAS:Formula:C13H9FN2O4Purity:98%Color and Shape:SolidMolecular weight:276.22Beclotiamine Hydrochloride
CAS:Controlled ProductApplications Beclotiamine is a Thiamine based compound that acts as a thiamine antagonist. Beclotiamine is used as a coccidiostatic. References Komai, T. et al.: J. Vitaminol., 18, 102 (1972); Matsuzawa, T.: Parasitology, 77, 235 (1978); Matsuzawa, T. et al.: Sank. Kenk. Nenpo, 24, 136 (1972);Formula:C12H16ClN4S·Cl·ClHColor and Shape:WhiteMolecular weight:355.71Ethyl 5-(3,3-Dimethylguanidino)-2-hydroxypentanoate
Controlled ProductApplications Ethyl 5-(3,3-Dimethylguanidino)-2-hydroxypentanoate is an impurity formed in the synthesis of 5-[[(Dimethylamino)iminomethyl]amino]-2-oxopentanoic Acid (D471015), a metabolite of asymmetric dimethylarginine. References Martens-Lobenhoffer, J. et al.: Anal Biochem., 419, 234 (2011)Formula:C10H21N3O3Color and Shape:NeatMolecular weight:231.2910-Deacetyl Cephalomannine
CAS:Applications 10-Deacetyl Cephalomannine is a derivative of Cephalomannine (C258500). References Liu, J., et al.: J. Pharm. Biomed. Anal., 15, 1729 (1997), Montero, A., et al.: Lancet Oncol., 6, 229 (2005), Ojima, I., et al.: J. Nat. Prod. 72, 554 (2009),Formula:C43H51NO13Color and Shape:NeatMolecular weight:789.86N-Nitroso Ticagrelor EP Impurity B (N-Nitroso Ticagrelor USP Related Compound B)
Formula:C23H27F2N7O5SMolecular weight:551.57alfa-Oxo-1,3-Benzodioxole-5-Acetic Acid
CAS:Formula:C9H6O5Color and Shape:White To Off-White SolidMolecular weight:194.141-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS:Formula:C10H14N2O6Purity:98%Color and Shape:SolidMolecular weight:258.228Metoprolol EP Impurity O-d7 HCl (Metoprolol USP Related Compound D-d7) (Mixture of Diastereomers)
CAS:Formula:C27H34D7NO6·HClMolecular weight:482.67 36.46Memantine hydrochloride
CAS:Controlled ProductFormula:C12H21N·ClHColor and Shape:NeatMolecular weight:215.76p-Amino-L-phenylalanine
CAS:Formula:C9H12N2O2Purity:98%Color and Shape:SolidMolecular weight:180.20381,1'-(Hexane-1,6-diyl)bis(1H-pyrrole-2,5-dione)
CAS:Formula:C14H16N2O4Purity:97%Color and Shape:SolidMolecular weight:276.28783-Oxo-4-aza-5α-androstan-17β-carboxylic Acid
CAS:Formula:C19H29NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:319.453-Bromo-7-chloro Hydroxychloroquine
CAS:Controlled ProductFormula:C18H25BrClN3OColor and Shape:NeatMolecular weight:414.772-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, methanesulfonate (1:1)
CAS:Formula:C24H28N2O7S2Purity:99%Color and Shape:SolidMolecular weight:520.6183DMT-2'-O-methyl-rC(Ac) Phosphoramidite
CAS:Formula:C42H52N5O9PPurity:>95.0%(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:801.88Benzylpenicillin Benzathine Tetrahydrate (Penicillin G Benzathine Tetrahydrate)
CAS:Formula:C16H18N2O4S·C16H20N2·4H2OMolecular weight:334.40 240.35 4*18.024-Phenyl-1-butanol
CAS:Applications 4-Phenyl-1-butanol is used as a reagent in the synthesis of substituted pyrrolidine-2-carboxylic acids which are used in the treatment of AT2 receptor function associated diseases. References McCarthy, T.D., et al. PCT Int. Appl. WO 2013102242 A1 20130711. Jul 11, 2013Formula:C10H14OColor and Shape:NeatMolecular weight:150.22Rosuvastatin-d3 sodium salt
CAS:Formula:C22H24D3FN3O6S·NaColor and Shape:Yellow SolidMolecular weight:483.56 22.99Dehydroabietic Acid
CAS:Formula:C20H28O2Color and Shape:White To Off-White SolidMolecular weight:300.44Alverine Citrate
CAS:Formula:C20H27N·C6H8O7Purity:>95.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:473.57Medroxy Progesterone 17-Acetate
CAS:Controlled ProductImpurity Megestrol Acetate EP Impurity A Applications Progestogen; an injectable contraceptive. Megestrol Acetate EP Impurity A. References Tang, M., et al.: Endocrinol., 151, 1320 (2010), Lee, K., et al.: Mol. Cell. Endocrinol., 319, 109 (2010), Rodgers, A., et al.: Chem., Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),Formula:C24H34O4Color and Shape:WhiteMolecular weight:386.527-Chloro-1-cyclopropyl-4-oxo-6-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic Acid Hydrochloride
CAS:Controlled ProductImpurity Ciprofloxacin USP Related Compound A / EP Impurity D Stability Hygroscopic Applications 7-Chloro-1-cyclopropyl-4-oxo-6-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic Acid Hydrochloride is an impurity in the synthesis of Ciprofloxacin (C482500), a fluorinated quinolone antibacterial. References Hoffken, G., et al.: Antimicrob. Ag. Chemother., 27, 375 (1985), Scully, B.E., et al.: Lancet, 1, 819 (1986)Formula:C17H18ClN3O3·ClHColor and Shape:NeatMolecular weight:384.262-[4-(1,2,4,5-Tetrazin-3-yl)phenyl]-N-[2-[2-[2-(prop-2-yn-1-yloxy)ethoxy]ethoxy]ethyl]acetamide
Formula:C19H23N5O4Purity:>95.0%(qNMR)Color and Shape:Light red to Red powder to crystalMolecular weight:385.42L-Tryptophan, N-acetyl-, methyl ester
CAS:Formula:C14H16N2O3Purity:98%Color and Shape:SolidMolecular weight:260.2884tert-Butyl (5-Aminobicyclo[3.1.1]heptan-1-yl)carbamate
CAS:Formula:C12H22N2O2Purity:>97.0%(GC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:226.32Noribogaine Glucuronide Lithium Salt
CAS:Formula:C25H31N2O7·LiColor and Shape:Pale Orange SolidMolecular weight:471.53 6.94Daidzein-3',5',8-d3
CAS:Controlled ProductApplications Daidzein-3',5',8-d3 is labelled Daidzein (D103500) which is an inactive analog of Genistein (Cat. #G350000). It blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. References Jones, P., et al.: J. Biol. Chem., 274, 32008 (1999), Hassan, M., et al.: Anticancer Res., 19, 5657 (1999), Salti, G., et al.: Eur. J . Cancer, 36, 796 (2000).Formula:C152H3H7O4Color and Shape:Off-White To GreyMolecular weight:257.26Pilocarpic Acid Sodium Salt
CAS:Controlled ProductImpurity Pilocarpine Hydrochloride EP Impurity B Stability Hygroscopic Applications Pilocarpic Acid Sodium Salt is an imidazole derivative used in the preparation of novel sequentially labile pilocarpine prodrugs for improved ocular delivery. References Bungaard, H. et al.: J. Med. Chem., 28, 978 (1985); Jarvinen, T.e t al.: Int. J. Pharmac., 79, 233 (1992);Formula:C11H17N2O3·NaColor and Shape:WhiteMolecular weight:248.252-Chloro-3-nitrobenzoic Acid
CAS:Controlled ProductApplications 2-Chloro-3-nitrobenzoic Acid is used in rapid, efficient and selective reduction of aromatic nitro compounds with hydrazine hydrate in the presence of the plain and supported platinum nanoparticles as catalysts as reactant/reagent. References Mehdizadeh, S., et al.: J. Iran. Chem. Soc., 11, 1587-1592 (2014)Formula:C7H4ClNO4Color and Shape:NeatMolecular weight:201.56(R)-Ozanimod HCl
CAS:Formula:C23H24N4O3·HClColor and Shape:Off-White SolidMolecular weight:404.47 36.46Diethyl 2-Propynylmalonate
CAS:Formula:C10H14O4Purity:>97.0%(GC)Color and Shape:Colorless to Almost colorless clear liquidMolecular weight:198.22DBCO-PEG3-amine (contains 5% Acetonitrile at maximum)
CAS:Formula:C27H33N3O5Purity:>75.0%(qNMR)Color and Shape:Light yellow to Yellow powder to lump to clear liquidMolecular weight:479.58Despropylrotigotine
CAS:Controlled ProductFormula:C16H19NOSColor and Shape:NeatMolecular weight:273.39Latanoprost Epoxide (Mixture of Diastereomers)
Formula:C26H40O6Color and Shape:Colorless LiquidMolecular weight:448.60Valacyclovir Related Compound D (2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9yl)methoxy]ethyl N-ethyl-L-valinate)
CAS:Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoiFormula:C15H24N6O4Color and Shape:White PowderMolecular weight:352.1859D-(-)-Leucinol
CAS:Formula:C6H15NOPurity:>97.0%(GC)(T)Color and Shape:Colorless to Light yellow to Light orange clear liquidMolecular weight:117.19D-Cysteine
CAS:Formula:C3H7NO2SPurity:>95.0%(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:121.152,5-Bis(trifluoromethyl)aniline
CAS:Controlled ProductApplications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000). References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);Formula:C8H5F6NColor and Shape:ColourlessMolecular weight:229.124H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-
CAS:Formula:C21H20O9Purity:%Color and Shape:SolidMolecular weight:416.3781Ubenimex Hydrochloride [for Biochemical Research]
CAS:Formula:C16H24N2O4·HClPurity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:344.844-Hydroxybenzhydrazide
CAS:Formula:C7H8N2O2Color and Shape:White To Off-White SolidMolecular weight:152.155-Methyl-N-[2-(trifluoromethyl)phenyl]isoxazole-4-carboxamide
CAS:Controlled ProductFormula:C12H9F3N2O2Color and Shape:NeatMolecular weight:270.213-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine
CAS:Controlled ProductFormula:C6H3F3N4Color and Shape:NeatMolecular weight:188.11L-Ascorbic Acid (Vitamin C)
CAS:Formula:C6H8O6Color and Shape:White To Off-White SolidMolecular weight:176.126,6-Dibromopenicillanic Acid S,S-Dioxide
CAS:Controlled ProductImpurity Sulbactam EP Impurity E Applications 6,6-Dibromopenicillanic Acid S,S-Dioxide (Sulbactam EP Impurity E) is an impurity of the semi-synthetic β-lactamase inhibitor Sulbactam (S699185). References Blanco Gomis, D. et al.: Anal. Chim. Acta, 498, 1 (2003); Hernadi, F. et al.: Am. Biotechnol. Lab., 3, 10 (1985);Formula:C8H9Br2NO5SColor and Shape:NeatMolecular weight:391.03Desfluoromethyl Fluticasone Propionate Disulfide
CAS:Impurity Fluticasone EP Impurity H Applications Desfluoromethyl Fluticasone Propionate Disulfide is the disulfide conjugated dimer of Fluticasone Propionate (F599500), a derivative of flumethasone and an anti-inflammatory agent. References Mistry, N., et al.: J. Pharma. Biomed. Anal., 19, 511 (1999); Dalvi, P., et al.: J. Chem., 20, 187 (2008);Formula:C48H58F4O10S2Color and Shape:Off-White To Light YellowMolecular weight:935.09(16Alpha)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
CAS:Controlled ProductFormula:C24H30O6Color and Shape:NeatMolecular weight:414.49
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