Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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(16Alpha)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
CAS:Controlled ProductFormula:C24H30O6Color and Shape:NeatMolecular weight:414.49Umeclidinium Bromide Impurity 6 Bromide
Formula:C44H54N2O3·2BrColor and Shape:White To Off-White SolidMolecular weight:658.93 2*79.90CHLOROACETYL-DL-NORLEUCINE
CAS:Formula:C8H14ClNO3Purity:99%Color and Shape:SolidMolecular weight:207.6547NHS-Diazirine
CAS:Formula:C9H11N3O4Color and Shape:White to Light yellow powder to crystalMolecular weight:225.20Dextroamphetamine Related Compound A (1-Phenyl-2-propanol)
CAS:Aromatic alcohols and their halogenated, sulfonated, niFormula:C9H12OColor and Shape:Colorless LiquidMolecular weight:136.08882cis-4-Aminocyclohexanol Hydrochloride
CAS:Controlled ProductApplications cis-4-Aminocyclohexanol used in the preparation of potential hypertensive agents and other biologically active compounds. References Chan, K.L. et al.: As. J. Pharmacol. Sci., 1, 91 (1979);Formula:C6H13NO·ClHColor and Shape:NeatMolecular weight:151.633,4-Dihydro Doramectin
Controlled ProductApplications 3,4-Dihydro-25-cyclohexyl-5-O-demethyl-25-de-(1-methylpropyl) Avermectin A1a is the impurity of the drug Doramectin (D534500), which is biosynthetic antiparasitic antibiotic structurally related to the avermectins (A794665). References Dutton, C.J., et al.: J. Antibiot., 44, 357 (1991); Lavy, E., et al.: Res. Vet. Sci., 75, 217 (2003);Formula:C50H76O14Color and Shape:White To Off-WhiteMolecular weight:901.13(1S,3S,5S,2’R)-Saxagliptin
CAS:Formula:C18H25N3O2Color and Shape:White To Off-White SolidMolecular weight:315.42Gal[2346Ac]β(1-3)GalN3-β-MP
Formula:C27H35N3O15Purity:min. 95.0 area%(HPLC)Color and Shape:SolidMolecular weight:641.582-(4-Methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-ethanone
CAS:Applications This compound is an impurity in the synthesis of Etoricoxib (E934100), a specific inhibitor of COX-2 . References McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002), Chenevard, R., et al.: Circulation, 107, 405 (2003)Formula:C15H15NO3SColor and Shape:BeigeMolecular weight:289.35(S)-N,N-Dimethyl Amphetamine Hydrochloride (1mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C11H17N·ClHColor and Shape:Single SolutionMolecular weight:199.721,1-Dimethyl-1-propanol-d6
CAS:Controlled ProductFormula:C5H6D6OColor and Shape:NeatMolecular weight:94.19Dofetilide Related Compound D (4-{2-[(4-Aminophenethyl)(methyl)amino]ethoxy}aniline)
CAS:Amino-naphthols and other amino-phenols, their ethers and esters, other than those cont more than one kind of oxygen function; salts thereof, nesoiFormula:C17H23N3OColor and Shape:Off-White PowderMolecular weight:285.1841111-cis-Retinoic Acid
CAS:Controlled ProductStability Light Sensitive, Temperature Sensitive Applications A retinoid compound with reduced toxicity than the starting or parent retinoid. References Carter, H.E., et al.: J. Biol. Chem., 175, 683 (1943)Formula:C20H28O2Color and Shape:White To YellowMolecular weight:300.44Monensin Methyl Ester
CAS:Controlled ProductApplications Monensin Methyl Ester is a neutral analog of monensin. An Ionophore. Also, it has the ability to complex formation with divalent cations which was studied by the ESI mass spectrometry and PM5 semiempirical calculation. References Lee, H. J., et al.: Anal. Sci. Technol., 8, 623-630 (1995); Huczynski, A., et al.: J. Mol. Struct., 788, 176-183 (2006)Formula:C37H64O11Color and Shape:NeatMolecular weight:684.898Descladinose 6-N-Desmethyl Azithromycin
CAS:Stability Hygroscopic Applications Descladinose 6-N-Desmethyl Azithromycin is a metabolite of Azithromycin (A927018), which is an azalide macrolide antibiotic. References Hunter, R., et al.: J. Vet. Pharmacol. Ther., 26, 117 (2003);Formula:C29H56N2O9Color and Shape:WhiteMolecular weight:576.76Nebivolol Related Compound 3 HCl (Mixture of (RS,SR), (SR,SR) and (SR,RS) Isomers)
Formula:C22H25F2NO4·HClColor and Shape:White To Off-White SolidMolecular weight:405.45 36.463-(N-Methyl-N-pentylamino)propionic Acid Hydrochloride
CAS:Controlled ProductApplications An intermediate in the preparation of biphosphonate drugs used in the prevention and treatment of osteoporosis. References Reddy, V.V. et al.: Ind. J. Chem. Sec. B Org. Chem. Incl. Med. Chem., 49B, 1257 (2010);Formula:C9H19NO2·ClHColor and Shape:White To Off-WhiteMolecular weight:209.71Neomycin B-LP Acetate Salt Hydrate
Applications Neomycin B-LP Acetate Salt Hydrate is a derivative of Neomycin (N389975) which is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.Formula:C25H48N6O14·x(C2H4O2)y(H2O)Color and Shape:NeatMolecular weight:656.68 + x(44.05) + y(18.02)Perphenazine
CAS:Formula:C21H26ClN3OSPurity:>97.0%(T)(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:403.97PBDE 203
CAS:Controlled ProductApplications PBDE 203 is a related compound of PBDE 37 (P215200). PBDE 37 is a polybrominated diphenyl ether, an organobromine compound, used as a flame retardant in consumer products. PBDE 37 is also an environment pollutant that may lead to pregnancy failure. References Lefevre, P. L. C., et al.: Biol. Reprod. 94, 9/1 (2016); Zou, Y., et al.: Environ. Sci. Technol. 50, 1359 (2016)Formula:C12H2Br8OColor and Shape:White To Off-WhiteMolecular weight:801.38Boc-5-Aminopentanoic Acid
CAS:Formula:C10H19NO4Purity:97%Color and Shape:SolidMolecular weight:217.26222-Chlorophenyl Cyclopentyl-d9 Ketone
CAS:Controlled ProductFormula:C12H4D9ClOColor and Shape:NeatMolecular weight:217.74Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride
CAS:Formula:C7H14ClNO2Purity:95%Color and Shape:SolidMolecular weight:179.6446Bosentan USP Related Compound E
CAS:Formula:C10H15NO2SColor and Shape:White To Off-White SolidMolecular weight:213.30Methyl 1,4-Benzodioxan-2-carboxylate
CAS:Applications Methyl 1,4-Benzodioxan-2-carboxylate is an intermediate used to prepare 2,3-dihydrobenzo[b|[1,4|dioxin- and indolealkylamine derivatives as potential antidepressants. References Wang, S., et al.: Archiv der Pharmazie (Weinheim, Germany), 347, 32 (2014); Wang, S., et al.: Bioorg. Med. Chem. Lettt., 24, 1766 (2014)Formula:C10H10O4Color and Shape:Colourless To Off-WhiteMolecular weight:194.185-(Ethylthio)-1H-tetrazole
CAS:Formula:C3H6N4SPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:130.17Benzoic acid, 2-(2-aminobenzoyl)-
CAS:Formula:C14H11NO3Purity:98%Color and Shape:SolidMolecular weight:241.242Halobetasol Propionate
CAS:Formula:C25H31ClF2O5Color and Shape:Off-White SolidMolecular weight:484.96seco-Ivabradine Amino Acid Sodium
CAS:Controlled ProductFormula:C27H37N2O6·NaColor and Shape:NeatMolecular weight:486.60Nα-(tert-Butoxycarbonyl)-D-asparagine
CAS:Formula:C9H16N2O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:232.24N-[(1R)-2-[3-(Aminosulfonyl)-4-methoxyphenyl]-1-methylethyl]-2-bromoacetamide
CAS:Formula:C12H17BrN2O4S(2S,4R)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
CAS:Formula:C10H19NO4Purity:97%Color and Shape:SolidMolecular weight:217.2622Ref: IN-DA0035D7
1g21.00€5g33.00€10g50.00€1kgTo inquire25g93.00€2kgTo inquire50g139.00€100g198.00€500gTo inquire250mgTo inquire4-Oxo Tretinoin-d6 (4-Oxo Retinoic Acid-d6) and Isotretinoin EP Impurity H-d6 (4-Oxo-13-cis-Retinoic Acid-d6)
CAS:Formula:C20H20D6O3Molecular weight:320.46Mono(3-carboxypropyl) Phthalate-d4
CAS:Controlled ProductApplications An isotope labelled derivative of Mono(3-carboxypropyl) Phthalate, a urinary phthalate metabolite. References Engel, S., et al.: NeuroToxicol., 30, 522 (2009), Samandar, E., et al.: Environ. Res., 109, 641 (2009), Berman, T., et al.: Environ. Int., 35, 353 (2009),Formula:C12D4H8O6Color and Shape:NeatMolecular weight:256.243,6-Dichloro-1,2,4,5-tetrazine
CAS:Formula:C2Cl2N4Purity:97%Color and Shape:SolidMolecular weight:150.9542Diazepam 1000 µg/mL in Methanol
CAS:Controlled ProductFormula:C16H13ClN2OColor and Shape:Single SolutionMolecular weight:284.746-O-Methyl Codeine (1mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C19H23NO3Color and Shape:Single SolutionMolecular weight:313.392-Acetylthioethanesulfonic Acid-d4 Sodium Salt
CAS:Controlled ProductApplications Labelled 2-acetylthioethanesulfonic acid. Mesna (M225750) impurity.Formula:C4D4H3NaO4S2Color and Shape:NeatMolecular weight:210.24Harmol
CAS:Formula:C12H10N2OPurity:>98.0%(T)Color and Shape:White to Yellow powder to crystalMolecular weight:198.23Moexipril Related Compound F ((S)-2-[(S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino]propanoic acid)
CAS:Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormula:C15H21NO4Color and Shape:White PowderMolecular weight:279.14706(2R)-alpha-Tocopherol (Mixture of Diastereomers)
CAS:Controlled ProductApplications (2R)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. References Kiyose, C. et al.: Lipids., 30, 1015 (1995); Bianchi, G., et al.: Eur. J. Lipid Sci. Technology, 105, 229 (2003);Formula:C29H50O2Color and Shape:NeatMolecular weight:430.714-APB Hydrochloride
CAS:Controlled ProductStability Hygroscopic Applications 4-APB (Hydrochloride) is a positional isomer of 6-APB (Hydrochloride) (CAS: 286834-84-2). 6-APB is found in recreational drugs of abuse. References Stanczuk, A.,et al.: Drug Test Anal., 5, 270 (2013)Formula:C11H13NO·HClColor and Shape:NeatMolecular weight:211.701,2,6-Hexanetriol
CAS:5x20kgFormula:C6H14O3Purity:>96.0%(GC)Color and Shape:Colorless to Light yellow to Light orange clear liquidMolecular weight:134.18Shikimic Acid Related Compound 5
CAS:Formula:C7H10O5Color and Shape:White To Off-White SolidMolecular weight:174.15Trichloro Bisphenol S
CAS:Controlled ProductApplications Trichloro Bisphenol S is an endocrine disruptor with estrogenic activity. References Kuruto-Niwa, R., et al.: Environ. Toxicol. Pharmacol., 19, 121 (2005); Zheng, S., et al.: Water Res., 132, 167 (2018)Formula:C12H7Cl3O4SColor and Shape:NeatMolecular weight:353.612-(2-Iodobenzamido)acetic acid
CAS:Formula:C9H8INO3Purity:99%Color and Shape:SolidMolecular weight:305.06929-Oxofolic Acid
CAS:Stability Hygroscopic Applications 9-Oxofolic Acid is a derivative of Folic Acid (F680300) which is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA. Folic Acid also acts as a cofactor in biological reactions involving folate. References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),Formula:C19H17N7O7Color and Shape:NeatMolecular weight:455.38Bivalirudin Des-Gly Fragment Trifluoroacetic Acid Salt (Impurity)
Controlled ProductStability Hygroscopic Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin. References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);Formula:C96H135N23O32•xC2HF3O2Color and Shape:NeatMolecular weight:2123.23Acetyl Isoniazid-d4
CAS:Controlled ProductApplications A labelled metabolite of Isoniazid (I821450) in plasma. References Peloquin, C., et al.: Antimicrob. Agents Chemother., 41, 2670 (1997), Peloquin, C., et al.: Drugs, 62, 2169 (2002),Formula:C8H5D4N3O2Color and Shape:Off-WhiteMolecular weight:183.2Diphenhydramine Related Compound A (2-(Diphenylmethoxy)-N-methylethanamine hydrochloride)
CAS:Amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters, salts thereof, nesoiFormula:C16H19NO·HClColor and Shape:White Crystalline PowderMolecular weight:241.146667-Chloro-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine (1mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C15H13ClN4Color and Shape:Single SolutionMolecular weight:284.74Desmopressin Trifluoroacetate
CAS:Formula:C46H64N14O12S2·C2HF3O2Color and Shape:Off-White SolidMolecular weight:1069.24 114.02
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