Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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7-Chloro-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine (1mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C15H13ClN4Color and Shape:Single SolutionMolecular weight:284.74Desmopressin Trifluoroacetate
CAS:Formula:C46H64N14O12S2·C2HF3O2Color and Shape:Off-White SolidMolecular weight:1069.24 114.02Ibuprofen
CAS:Formula:C13H18O2Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:206.29Octadecamethylnonasiloxane
CAS:Controlled ProductFormula:C18H54O9Si9Color and Shape:Colourless To Light YellowMolecular weight:667.39(+)-Allococaine Hydrochloride
CAS:Controlled ProductFormula:C17H21NO4·HClColor and Shape:NeatMolecular weight:339.814Cilostazol Metabolite (OPC-13213)
CAS:Formula:C20H27N5O3Color and Shape:White To Off-White SolidMolecular weight:385.47Tauroursodeoxycholic Acid-d4 (Tauroursodiol-d4)
CAS:Formula:C26H41D4NO6SColor and Shape:White To Off-White SolidMolecular weight:503.73Boc-3-(2 naphthyl)-L-alanine
CAS:Formula:C18H21NO4Purity:97%Color and Shape:SolidMolecular weight:315.3636Phenylsulfate-d5 Sodium Salt
CAS:Formula:C6D5O4S·NaColor and Shape:White To Off-White SolidMolecular weight:178.19 22.99Sofosbuvir Impurity 19
CAS:Formula:C22H29FN3O9PColor and Shape:White To Off-White SolidMolecular weight:529.46Loratadine N-Oxide
CAS:Formula:C22H23ClN2O3Color and Shape:White To Off-White SolidMolecular weight:398.89Alpha-Methyldopa Methyl Ester
CAS:Controlled ProductApplications α-Methyldopa Methyl Ester is an impurity in the synthesis of L-α-Methyl DOPA Methyl Ester Hydrochloride which is a Methyldopa angiotensin II analog. References Karle, I., et al.: Biochemistry, 29, 6747 (1990), Biron, E., et al.: Bioorg. Med. Chem., 12, 1279 (2004),Formula:C11H15NO4Color and Shape:Yellow To Dark BrownMolecular weight:225.244-Methyl Irinotecan
Controlled ProductApplications 4-Methyl Irinotecan, is an impurity of Irinotecan (I767500), a DNA topoisomerase inhibitor. References Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987), Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993)Formula:C34H40N4O6Color and Shape:NeatMolecular weight:600.70tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent]
CAS:Formula:C6H15ClSiPurity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:150.72Benazepril HCl
CAS:Formula:C24H28N2O5·HClColor and Shape:White To Off-White SolidMolecular weight:424.50 36.46Enpiroline HCl
CAS:Formula:C19H18F6N2O·HClColor and Shape:White To Off-White SolidMolecular weight:404.36 36.46Enobosarm-d4
CAS:Formula:C19H10D4F3N3O3Color and Shape:White To Off-White SolidMolecular weight:393.361-(4-Methoxyphenyl)piperazine-d8
CAS:Controlled ProductApplications An intermediate in the synthesis of Itraconazole (I937500).Formula:C11H8D8N2OColor and Shape:NeatMolecular weight:200.31N-Isopropylaniline-d5
CAS:Controlled ProductFormula:C9H8D5NColor and Shape:NeatMolecular weight:140.24Lactose (Mixture of α and β Isomers)
CAS:Formula:C12H22O11Color and Shape:White To Off-White SolidMolecular weight:342.30Polyallylamine Hydrochloride (2-Propen-1-amine, hydrochloride (1:1), homopolymer)
CAS:Polysulfides, polysulfones & oth products spec in note 3, chapter 39, except elastomericFormula:(C3H7N)n·nHClColor and Shape:White Light Yellow PowderMolecular weight:93.55 g/molQuinapril EP Impurity C-d5 (Quinapril USP Related Compound B-d5, Quinaprilat-d5)
CAS:Formula:C23H21D5N5O5Color and Shape:White To Off-White SolidMolecular weight:415.50Benserazide HCl
CAS:Formula:C10H15N3O5·HClColor and Shape:Off-White SolidMolecular weight:257.25 36.46N-(Triphenylmethyl)glycine
CAS:Formula:C21H19NO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:317.39Spinosad (Mixture of Spinosyn A and Spinosyn D)
CAS:Formula:C41H65NO10C42H67NO10Color and Shape:White To Off-White SolidMolecular weight:731.97 746.00S(-)-BZM Hydrochloride
CAS:Controlled ProductApplications S(-)-BZM Hydrochloride is a precursor to radio-iodinated S(-)-IBZM, a D2 dopamine receptor ligand. References Kung, H., et al.: J. Med. Chem., 31, 1039 (1988); Zea-Ponce, Y., et al.: Nucl. Med. Biol., 26, 661 (1999); Radau, P., et al.: J. Nucl. Med., 41, 220 (2000)Formula:C15H23ClN2O3Color and Shape:NeatMolecular weight:314.816-Acetyl Morphine
CAS:Controlled ProductApplications A metabolite of Heroin (H281180). Controlled substance. References Oldendorf, W., et al.: Science, 178, 984 (1972), Selley, D., et al.: Biochem. Pharmacol., 62, 447 (2001), Girardin, F., et al.: Clin. Pharmacol. Ther., 74, 341 (2003), Ferrari, A., et al.: Pharmacol. Res., 50, 551 (2004),Formula:C19H21NO4Color and Shape:White To Light BeigeMolecular weight:327.374L-Valinamide Hydrochloride
CAS:Formula:C5H12N2O·HClPurity:>98.0%(T)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:152.621-Aminocyclobutanecarboxylic Acid Hydrochloride
CAS:Formula:C5H9NO2·HClPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:151.59Asenapine-13C-d3 HCl
CAS:Formula:C1613CH13D3ClNO·HClColor and Shape:White To Off-White SolidMolecular weight:289.78 36.46Melengestrol Acetate Related Compound B (6,16-Dimethylene-3,20-dioxopregn-4-en-17-yl acetate)
CAS:Estrogens and progestinsFormula:C25H32O4Color and Shape:White Yellow PowderMolecular weight:396.5Diflunisal
CAS:Formula:C13H8F2O3Purity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalineMolecular weight:250.20Pyridyl Urazol [4-(3-Pyridyl)-1,2,4-triazolidine-3,5-dione]
CAS:Formula:C7H6N4O2Color and Shape:White To Off-White SolidMolecular weight:178.15Fenofibric Acid 1,1-Dimethyl-2-(1-methylethoxy)-2-oxoethyl Ester
CAS:Controlled ProductImpurity Fenofibrate EP Impurity G; Fenofibrate USP Related Compound C Applications Fenofibric Acid 1,1-Dimethyl-2-(1-methylethoxy)-2-oxoethyl Ester (Fenofibrate EP Impurity G; Fenofibrate USP Related Compound C) is an impurity of Febofibrate (F248640). References Lacroix, P.M. et al.: J. Pharmac. Biomed. Anal., 18, 383 (1998);Formula:C24H27ClO6Color and Shape:White To Light YellowMolecular weight:446.921H-Indole-3-propanamide, a-amino-, monohydrochloride, (aS)-
CAS:Formula:C11H14ClN3OPurity:95%Color and Shape:SolidMolecular weight:239.7014Artemisinic Aldehyde
CAS:Formula:C15H22OColor and Shape:White To Off-White SolidMolecular weight:218.34Triflusal
CAS:Formula:C10H7F3O4Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:248.16Ethyl (Benzyloxy)acetate
CAS:Formula:C11H14O3Purity:>98.0%(GC)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:194.23Ref: 4Z-M-1632
Discontinued productBlonanserin-d5
CAS:Formula:C23H25D5FN3Color and Shape:White To Off-White SolidMolecular weight:372.54Sulfamethazine Sodium Salt
CAS:Formula:C12H13N4NaO2SPurity:>97.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:300.31Brimonidine Acrylate
Controlled ProductApplications Brimonidine Acrylate is an impurity of Brimonidine ( B677520). Brimonidine ( B677520) is an α2 receptor agonist. It is a drug used to treat glaucoma. References Katz, L.J., et al.: Am. J. Ophthalmol., 127, 20 (1999); Cantor, L. B., Expert Opin. Pharmacother., 1, 815 (2000);Formula:C14H14BrN5O2Color and Shape:NeatMolecular weight:364.197(R)-α-Lipoic Acid
CAS:Formula:C8H14O2S2Purity:>98.0%(T)(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalineMolecular weight:206.32Lurasidone HCl
CAS:Formula:C28H36N4O2S·HClColor and Shape:White To Off-White SolidMolecular weight:492.68 36.46(R)-Fesoterodine-d7 Fumarate
Formula:C26H30D7NO3·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:418.63 116.077-Amino Clonazepam
CAS:Controlled ProductApplications The major metabolite of Clonazepam (C587080). References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),Formula:C15H12ClN3OColor and Shape:YellowMolecular weight:285.73Isopropyl Paraben
CAS:Applications An antimicrobial agent used in cosmetic products. References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),Formula:C10H12O3Color and Shape:Off-WhiteMolecular weight:180.20Desethyl Sildenafil
CAS:Controlled ProductImpurity Sildenafil EP Impurity C Applications Desethyl Sildenafil (Sildenafil EP Impurity C) is a metabolite of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor. References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)Formula:C20H26N6O4SColor and Shape:WhiteMolecular weight:446.526-Chloro-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS:Controlled ProductFormula:C7H9ClN2O2Color and Shape:Neat3,6-Dimethyl-1,2,4,5-tetrazine
CAS:Formula:C4H6N4Purity:>98.0%(GC)Color and Shape:Orange to Brown to Dark red powder to crystalineMolecular weight:110.121-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine
CAS:Formula:C12H19NO4SPurity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:273.35Mucopolysaccharidosis Type I Related Compound MPS-I-3 (IdA-IS)
Formula:C19H24N2O6Molecular weight:376.41L-Histidine, monohydrochloride, monohydrate
CAS:Formula:C6H12ClN3O3Purity:98%Color and Shape:SolidMolecular weight:209.6308Fluconazole Related Compound C (1,1'-(1,3-phenylene)di(1H-1,2,4-triazole))
CAS:Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFormula:C10H8N6Color and Shape:White PowderMolecular weight:212.08104Valbenazine
CAS:Controlled ProductApplications Valbenzine is a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia. References O'Brien, C. et al.: Movement Dis., 30, 1681 (2015);Formula:C24H38N2O4Purity:~90%Color and Shape:NeatMolecular weight:418.573H-Pyrazol-3-one, 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-
CAS:Formula:C12H14N2OPurity:97%Color and Shape:SolidMolecular weight:202.2524O-tert-Butyl-L-serine tert-Butyl Ester Hydrochloride
CAS:Formula:C11H23NO3·HClPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:253.77Darifenacin Related Compound G (5-(2-Bromoethyl)-2,3-dihydrobenzofuran)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C10H11BrOColor and Shape:White Pale Yellow PowderMolecular weight:225.99933Chloropheniramine Maleate
CAS:Formula:C20H23ClN2O4Purity:98%Color and Shape:SolidMolecular weight:390.8606199999999Sugammadex Disulfide Dimer (>85%)
Controlled ProductFormula:C138H214xNa·xO92S16Purity:>85%Color and Shape:NeatEnalapril maleate impurity C
CAS:Enalapril maleate impurity C (E-C) is an impurity of enalapril, a drug that inhibits angiotensin-converting enzyme. It has been shown to have antihypertensive activity in animals and humans. Enalapril maleate impurity C is found in wastewater and may be used as a marker for the presence of enalapril. The bioavailability of enalaprilat, which has been shown to have similar pharmacokinetics to captopril, can be determined by measuring the plasma concentrations of E-C in blood samples. This analytical method is useful for determining whether two drugs are bioequivalent.Formula:C18H24N2O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:348.39 g/molApixaban Related Compound E (Methyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate)
CAS:Lactams, nesoiFormula:C26H26N4O5Color and Shape:Off-White Light Brown Cream PowderMolecular weight:474.19032
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