Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
Sort by
N-Boc-4,7,10-trioxa-1,13-tridecanediamine
CAS:Formula:C15H32N2O5Purity:>95.0%(T)(qNMR)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:320.43N-Desmethyl Clomipramine Hydrochloride
CAS:Controlled ProductApplications A metabolite of Clomipramine. References McTavish, D., et al.: Drugs, 39, 136 (1990), Chauret, N., et al.: Drug Metab. Dispos., 25, 1130 (1997), Gex-Fabry, M., et al.: Ther. Drug Monit., 22, 701 (2000), Herrera, D., et al.: J. Clin. Pharmacol., 40, 1488 (2000),Formula:C18H21ClN2·ClHColor and Shape:Off-WhiteMolecular weight:337.29Macitentan Impurity 17
Formula:C15H17BrN4O3SColor and Shape:White To Off-White SolidMolecular weight:413.29Trichloro Bisphenol S
CAS:Controlled ProductApplications Trichloro Bisphenol S is an endocrine disruptor with estrogenic activity. References Kuruto-Niwa, R., et al.: Environ. Toxicol. Pharmacol., 19, 121 (2005); Zheng, S., et al.: Water Res., 132, 167 (2018)Formula:C12H7Cl3O4SColor and Shape:NeatMolecular weight:353.61Bivalirudin Des-Gly Fragment Trifluoroacetic Acid Salt (Impurity)
Controlled ProductStability Hygroscopic Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin. References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);Formula:C96H135N23O32•xC2HF3O2Color and Shape:NeatMolecular weight:2123.23Alizapride-13C-d3 HCl
CAS:Formula:C1513CH18D3N5O2·HClColor and Shape:White To Off-White SolidMolecular weight:319.39 36.46Milnacipran Related Compound C ((1RS ,2SR)-2-[(1,3-Dioxoisoindolin-2-yl)methyl]-N,N-diethyl-1-phenylcyclopropane-1-carboxamide)
CAS:Imides and their derivatives (excluding sacharin), salt thereofFormula:C23H24N2O3Color and Shape:SolidMolecular weight:376.1786911-(4-Ethyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine Dihydrochloride
CAS:Controlled ProductStability Hygroscopic Applications 11-(4-Ethyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine is an impurity of Quetiapine hemifumarate (Q510000), a dibenzothiazepine antipsychotic medication used in the treatment of schizophrenia. References Kumar, K., et al.: Org. Chem.: An Indian Journal, 8, 164 (2012); Raju, I., et al.: Chromatographia, 70, 545 (2009)Formula:C19H23Cl2N3SColor and Shape:NeatMolecular weight:396.38b-Hydroxyl Phentermine
CAS:Applications β-Hydroxyl Phentermine is derived from 2-Nitropropane (N519600), which is an oxidative stress-inducing agent and also a carcinogen. It is used in the induction of DNA polymerase β-dependent base excision repair in response to oxidative stress in the liver. References Cabelof, D.C., et al.: Carcinogenesis,23, 1419 (2002); Kreis, P., et al.: Carcinogenesis, 21, 295 (2000)Formula:C10H15NOColor and Shape:NeatMolecular weight:165.23Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-
CAS:Formula:C19H21NSPurity:98%Color and Shape:SolidMolecular weight:295.4417Allopurinol Related Compound A (3-Amino-4-carboxamidopyrazole Hemisulfate)
CAS:Compounds containing an unfused pyrazole ring, whether or not hydrogenated, in the structure, nesoiFormula:C4H6N4OH2O4SColor and Shape:Off-White Yellow PowderMolecular weight:350.31Antipyrine Related Compound A (3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one)
CAS:Aromatic or modified aromatic compounds containg an unfused pyrazolering (whether or not hydrogenated) in the structureFormula:C10H10N2OColor and Shape:White Pale Yellow PowderMolecular weight:174.07931Estriol 3,16a,17b-Triacetate
CAS:Controlled ProductApplications Estriol 3,16α,17β-Triacetate is a triacetate derivative of Estriol (E888960) with contraceptive activity. References Wotiz, H.H., et al.: J. Reprod. Fertil., 26, 363 (1971)Formula:C24H30O6Color and Shape:NeatMolecular weight:414.49N-Acetyl Iminostilbene
CAS:Formula:C16H13NOColor and Shape:White To Off-White SolidMolecular weight:235.291,3-Isobenzofurandione, 4-chloro-
CAS:Formula:C8H3ClO3Purity:95%Color and Shape:SolidMolecular weight:182.5606(2R)-2-[(3,5-dinitrophenyl)formamido]-2-phenylacetic acid
CAS:Formula:C15H11N3O7Purity:98%Color and Shape:SolidMolecular weight:345.26374DL-2-Aminopimelic Acid
CAS:Formula:C7H13NO4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:175.186-Azido-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-norleucine
CAS:Formula:C21H22N4O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:394.43Deferasirox Acyl β-D-Glucuronide
CAS:Formula:C27H23N3O10Color and Shape:Pale Yellow SolidMolecular weight:549.492-(3-(tert-Butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one (>90%)
CAS:Impurity Timolol EP Impurity H Applications 2-(3-(tert-Butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one is a impurity of Timolol (T443710), an antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent. References Lacroix, P.M., et. al.: Chirality, 6, 484 (1994); Wasson, et al.: J. Med. Chem., 15, 651 (1972); Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972); Heel, R.C., et al.: Drugs, 17, 38 (1979); Rofman, B.A., et al.: Hypertension, 2, 643 (1980); Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641 (1987)Formula:C13H24N4O3SPurity:>90%Color and Shape:NeatMolecular weight:316.42Etonogestrel Related Compound C (13-Ethyl-17β-hydroxy-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-3,6-dione)
CAS:Ketone-alcohols and ketone-aldehydes, nesoiFormula:C22H26O3Color and Shape:Light Yellow SolidMolecular weight:338.18819Ref: 4Z-A-331033
Discontinued productTigecycline (open C-ring D-ring) Quinone Trifluoroacetic Acid Salt
CAS:Controlled ProductApplications Tigecycline (open C-ring D-ring) quinone Trifluoroacetic Acid Salt is a salt of Tigecycline (open C-ring D-ring) quinone, an impurity of Tigecycline (T440015). Tigecycline (open C-ring D-ring) quinone is one of the very few glycylcycline antimicrobials that exhibit activity against Gram-negative bacteria and also one of the few that also circumvent around the major resistance mechanisms of tetracycline. References Grosse, E., et al.: Clin. Infect. Dis. (Supplement 5), 41, S341 (2005); Livermore, D.: J. Antimicrob. Chemoth., 56, 611 (2005); Stein, G. & Craig, W.: Clin. Infect. Dis., 43, 518 (2006)Formula:C26H32N4O8•x(C2HF3O2)Color and Shape:NeatMolecular weight:528.55 + x(114.02)4-Hydroxybenzhydrazide
CAS:Controlled ProductApplications 4-Hydroxybenzhydrazide works as an indicator in the determination of carbohydrates. Tissue (liver) bounded 4-Hydroxybenzhydrazide, the acid-hydrolyzable side chain of Nifuroxazide (N458500) can be used as a marker to monitor it’s residue in chicken. References Lever, M., et al.: Anal. Biochem., 139, 205 (1984); Rocco, M., et al.: Anal. Biochem., 377, 251 (2008); Gao, F., et al.: J. Sci. Food Agr., 93, 2172 (2013)Formula:C7H8N2O2Color and Shape:WhiteMolecular weight:152.15Pyridostigmine Bromide
CAS:Formula:C9H13BrN2O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:261.12(15R)-Bimatoprost
CAS:Applications An intermediate in the production of Bimatoprost (B386800).Formula:C25H37NO4Color and Shape:NeatMolecular weight:415.57Z-Lys(z)-OH
CAS:Formula:C22H26N2O6Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:414.46Noscapine Hydrochloride
CAS:Formula:C22H23NO7·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:449.88Triamcinolone-d5 (Triamcinolone Acetonide EP Impurity A-d5)
Formula:C21H22FO6D5Molecular weight:399.47Ranolazine Related Compound C (N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C14H21N3OColor and Shape:White PowderMolecular weight:247.168462-3-[4-(3-Bromophenyl)piperazin-1-yl]propyl-1,2,4-triazolo[4,3-a]-pyridin-3(2H)-one Hydrochloride
CAS:Formula:C19H22BrN5O·ClHPravastatin Ethyl Ester
CAS:Controlled ProductApplications Pravastatin Ethyl Ester is an impurity of Pravastatin(P702000). A competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of Mevastatin. References Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), Yoshino, G., et al.: Lancet, 2, 740 (1986), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)Formula:C25H40O7Color and Shape:NeatMolecular weight:452.582-[[[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl ]methyl]thio]-1H-benzimidazole
CAS:Formula:C18H21N3O2SPurity:97%Color and Shape:SolidMolecular weight:343.443240000000061,3-Cyclohexanedione, 2-acetyl-5,5-dimethyl-
CAS:Formula:C10H14O3Purity:98%Color and Shape:SolidMolecular weight:182.21636N-Desmethyl Ibandronate Sodium
CAS:Controlled ProductStability Very Hygroscopic Applications Ibandronate sodium (I120001) impurity. References Dunn, C., et al.: Drugs, 2001, 61, 685 (2001), Szabo, C., et al.: J. Med. Chem., 45, 2185 (2002),Formula:C8H20NO7P2·NaColor and Shape:WhiteMolecular weight:327.18Apixaban USP Related Compound H
CAS:Formula:C27H29ClN4O5Color and Shape:White To Off-White SolidMolecular weight:525.004-METHOXYPHENYL 2-AZIDO-3,6-DI-O-BENZYL-2-DEOXY-β-D-GLUCOPYRANOSIDE
CAS:Formula:C27H29N3O6Purity:98.0%Molecular weight:491.53573-Hydroxy Citalopram
CAS:Impurity Citalopram EP Impurity B Applications 3-Hydroxy Citalopram (Citalopram EP Impurity B) is a Citalopram (C505000) impurity.Formula:C20H21FN2O2Color and Shape:NeatMolecular weight:340.39N-Nitroso Cilazapril
CAS:Controlled ProductFormula:C22H30N4O6Color and Shape:NeatMolecular weight:446.5Sodium Ditaurinate
CAS:Formula:C4H9NO6S2·2NaColor and Shape:White To Off-White SolidMolecular weight:231.24 2*22.99Ketoprofen Tromethamine Amide
CAS:Formula:C20H23NO5Color and Shape:White To Off-White Stick SolidMolecular weight:357.41Di-tert-butyldichlorosilane
CAS:Formula:C8H18Cl2SiPurity:95%Color and Shape:LiquidMolecular weight:213.22Ref: IN-DA003PRU
1g67.00€5g155.00€10g216.00€15g313.00€25g595.00€50gTo inquire100gTo inquire100mg32.00€250mg51.00€N-Acetyl-DL-phenylalanine
CAS:Formula:C11H13NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:207.233-alfa 5-β-Dihydroxy-Pravastatin
CAS:Formula:C23H37O9NaColor and Shape:Off-White SolidMolecular weight:457.55 22.99N-Nitroso Tofenacin-d5
Controlled ProductApplications Isotope labelled Orphenadrine Nitrous is an impurity of Orphenadrine (O695300), a muscle relaxant and antihistaminic agent. References Harms, N., et al.: J. Med. Pharm. Chem., 2, 57 (1960),Formula:C17D5H15N2O2Color and Shape:Off-WhiteMolecular weight:289.384(3S,5R)-Pitavastatin Calcium Salt
CAS:Formula:C25H23FNO4·5CaColor and Shape:White To Off-White SolidMolecular weight:420.46 0.5*40.083'-p-Hydroxy Paclitaxel
CAS:Formula:C47H51NO15Color and Shape:White To Off-White SolidMolecular weight:869.922-Hydroxy-n-octanoic Acid
CAS:Formula:C8H16O3Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:160.21Leflunomide EP Impurity G
CAS:Controlled ProductFormula:C12H12N2O2Color and Shape:NeatMolecular weight:216.24Mevastatin Hydroxy Acid Sodium Salt
CAS:Controlled ProductStability Hygroscopic Applications An active carboxylate of Mevastatin (M340500). It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. References Endo, A. et al.: Atheroscler. Supp., 5, 39 (2004); Hosobuchi, M. et al.: J. Ferm. Bioeng., 76, 470 (1993);Formula:C23H35O6·NaColor and Shape:NeatMolecular weight:430.51Diphenhydramine-d6 N-Oxide
CAS:Controlled ProductApplications A labelled metabolite of Diphenhydramine (D486900) in humans. References Breyer-Pfaff, U., et al.: Drug Metab. Dispos., 25, 340 (1997),Formula:C17H15D6NO2Color and Shape:NeatMolecular weight:277.39Nepafenac Related Compound A (2-{2-Amino-3-[hydroxy(phenyl)methyl]phenyl}acetamide)
CAS:Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereofFormula:C15H16N2O2Color and Shape:White SolidMolecular weight:256.12118Terbinafine Related Compound 6
CAS:Formula:C9H13ClColor and Shape:Colorless LiquidMolecular weight:156.65Dexpanthenol-d6
CAS:Formula:C9H13D6NO4Color and Shape:White To Off-White SolidMolecular weight:211.29Levalbuterol Related Compound F ((R)-1-[4-(Benzyloxy)-3-(hydroxymethyl)phenyl]-2-(tert-butylamino)ethan-1-ol)
CAS:Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormula:C20H27N03Color and Shape:White Off-White SolidMolecular weight:309.2205N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide
CAS:Formula:C9H11F3N2O4Purity:97%Color and Shape:SolidMolecular weight:268.18984959999995Cilostazol Related Compound A (6-hydroxy-3,4-dihydro-1H-quinolin-2-one)
CAS:Lactams not elsewhere specified or includedFormula:C9H9NO2Color and Shape:Yellow White PowderMolecular weight:163.0633317-alfa,20-β-Dihydroxy Progesterone
CAS:Formula:C21H32O3Color and Shape:White To Off-White SolidMolecular weight:332.48Ref: 4Z-D-123006
Discontinued productMethocarbamol Glucuronide (Mixture of Diastereomers)
CAS:Formula:C17H23NO11Color and Shape:White To Off-White SolidMolecular weight:417.37
![Milnacipran Related Compound C ((1RS ,2SR)-2-[(1,3-Dioxoisoindolin-2-yl)methyl]-N,N-diethyl-1-phen…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F45%2Fthumb-webp%2F1443680.webp&w=3840&q=75)
![11-(4-Ethyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine Dihydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FE925790.webp&w=3840&q=75)
![Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA001O5K.webp&w=3840&q=75)
![(2R)-2-[(3,5-dinitrophenyl)formamido]-2-phenylacetic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA003C3H.webp&w=3840&q=75)
![6-Azido-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-norleucine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb-webp%2FA3023.webp&w=3840&q=75)
![2-[[[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl ]methyl]thio]-1H-benzimidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA007QM8.webp&w=3840&q=75)
![Levalbuterol Related Compound F ((R)-1-[4-(Benzyloxy)-3-(hydroxymethyl)phenyl]-2-(tert-butylamino)…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F45%2Fthumb-webp%2F1358842.webp&w=3840&q=75)
![N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00C0SG.webp&w=3840&q=75)
