Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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Dicyclohexyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine (X-Phos)
CAS:Formula:C33H49PMolecular weight:476.73N-(3-Azidopropyl)biotinamide (2mg×5)
CAS:Formula:C13H22N6O2SColor and Shape:White to Almost white powder to crystalMolecular weight:326.42Latanoprostene Bunod 5,6-Epoxide
Formula:C27H41NO9Color and Shape:Colorless OilMolecular weight:523.62N-Methyleflornithine (Mixture of Isomers)
Formula:C7H14F2N2O2C7H14F2N2O2Molecular weight:196.20 : 196.20(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid 1-Methylethyl Ester (>90%)
CAS:Controlled ProductFormula:C19H21NO2Purity:>90%Color and Shape:ColourlessMolecular weight:295.38L-(+)-Arginine
CAS:Formula:C6H14N4O2Purity:>99.0%(T)(HPLC)Color and Shape:White powder to crystalMolecular weight:174.20Propanamide, N-(2-methylphenyl)-2-(propylamino)-
CAS:Formula:C13H20N2OPurity:98%Color and Shape:SolidMolecular weight:220.3107H-Lys(Z)-OMe·HCl
CAS:Formula:C15H22N2O4·HClPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:330.81Abiraterone Acetate
CAS:Formula:C26H33NO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:391.56Ref: 4Z-C-277
Discontinued product8-Hydroxy Dihydro-Ergotamine (Mixture of Diastereomers)
CAS:Formula:C33H37N5O6Molecular weight:599.69(11b,16a,17a)-9-Chloro-17-(2,2-dioxido-5H-1,2-oxathiol-4-yl)-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-androsta-1,4-dien-3-one
CAS:Controlled ProductImpurity Mometasone Furoate EP Impurity B Stability Light Sensitive Applications (11β,16α,17α)-9-Chloro-17-(2,2-dioxido-5H-1,2-oxathiol-4-yl)-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-androsta-1,4-dien-3-one (Mometasone EP Impurity B) is an impurity of Mometasone Furoate, a topical corticosteroid used as an anti-inflammatory. References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987); Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)Formula:C28H31ClO8SColor and Shape:Off WhiteMolecular weight:563.063-Methyl-1-penten-4-yn-3-ol
CAS:Formula:C6H8OPurity:>98.0%(GC)Color and Shape:Colorless to Light yellow to Light orange clear liquidMolecular weight:96.13Adamantane
CAS:Applications Adamantane derivatives have been used to treat influenza, as well as serve as NMDA receptor channel blockers for a wide range of pharmaceutical application. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Wang, C. et al.: Inorg. Chem. 45, 4769 (2012); Thomas. A. et al.: J. Neurosci., 25, 3312 (2005); Deyde, V. et al.: Exp. Rev. Mol. Diag., 9, 493 (2009);Formula:C10H16Color and Shape:NeatMolecular weight:136.237-Hydroxy Propranolol Glucuronide (Mixture of Diastereomers)
CAS:Formula:C22H29NO9Color and Shape:White To Off-White SolidMolecular weight:451.48Olanzapine LIP 1 Acetyl
CAS:Applications Olanazpine LIP 1 Acetyl is an Olanazpine impurity. Olanazpine is an antipsychotic medicine. References Perera, V., et al.: Br. J. Clin. Pharmacol., 78, 800 (2014); Pratt, N., et al.: Pharmacoepidemiol. Drug Saf., 22, 915 (2013)Formula:C18H20N4OSColor and Shape:YellowMolecular weight:340.44N-Methylanilinium Trifluoroacetate
CAS:Formula:C7H9N·C2HF3O2Purity:>99.0%(T)Color and Shape:White to Light gray to Light yellow powder to crystalMolecular weight:221.18Carvedilol USP Related Compound E
CAS:Formula:C9H13NO2Color and Shape:Yellowish-Brown LiquidMolecular weight:167.21L-Alanine Ethyl Ester Hydrochloride
CAS:Formula:C5H11NO2·HClPurity:>98.0%(N)Color and Shape:White to Almost white powder to crystalMolecular weight:153.611-(1-Ethoxyethoxy) Propane
CAS:Formula:C7H16O2Color and Shape:Colorless LiquidMolecular weight:132.20Dabigatran Carboxamide
CAS:Controlled ProductApplications Dabigatran Carboxamide is an impurity of Dabigatran Etexilate Mesylate (D100150) which is a nonpeptide, direct thrombin inhibitor. References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002); Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002); Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005)Formula:C25H24N6O4Color and Shape:NeatMolecular weight:472.5Carbasalate Calcium Salt
CAS:Formula:C9H7O4·CH4N2O·CaColor and Shape:White To Off-White SolidMolecular weight:2 179.15 60.06 40.08Ref: 4Z-C-2749
Discontinued productFosphenytoin Disodium Salt
CAS:Formula:C16H13N2O6P·2NaColor and Shape:White To Off-White SolidMolecular weight:360.26 2*22.99(S)-Flecainide
CAS:Formula:C17H20F6N2O3Color and Shape:White To Off-White SolidMolecular weight:414.351H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)-
CAS:Formula:C16H18ClNO4Purity:98%Color and Shape:SolidMolecular weight:323.77141-Ethynylpyrene
CAS:Formula:C18H10Purity:>98.0%(GC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:226.28Trigonelline-D3 Hydrate
CAS:Controlled ProductApplications Trigonelline-D3 is an intermediate used in the synthesis of Trigonelline-d3 HCl (N-methyl-d3) (T794052), which is deuterium labelled Trigonelline HCl. Trigonelline HCl has utility in developing site-specific system that delivers drugs to the brain. It has also been suggested as a potential anti-Alzheimer disease agent. References Bodor, N., et al.: J. Med. Chem 26, 313 (1983); Makowska, J., et al.: J. Chromatogr. B 968, 101 (2014)Formula:C7H4D3NO2•xH2OColor and Shape:NeatMolecular weight:140.1518024-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]- (2S,5R,6R)-, sodium salt(1:1)
CAS:Formula:C16H17N2NaO4SPurity:97%Color and Shape:SolidMolecular weight:356.3719N-(tert-Butoxycarbonyl)-D-tyrosine
CAS:Formula:C14H19NO5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:281.31Rivaroxaban Aminomethyl Hydrochloride Impurity
CAS:Formula:C14H17N3O4HClMolecular weight:291.3 : 36.5FR 179642
CAS:Controlled ProductApplications FR 179642 is an impurity of Micafungin (M342350), a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. References Denning, D., et al.: J. Infection, 53, 337 (2006); Queiroz-Telles, F., et al.: Pediatr. Infect. Dis. J., 27, 820 (2008)Formula:C35H52N8O20SColor and Shape:NeatMolecular weight:936.89Perphenazine Related Compound B (2-{4-[3-(10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol)
CAS:Compounds (excluding drugs) containing a phenothiazine ring-system (whether or not hydrogenated), not further fusedFormula:C21H27N3OSColor and Shape:Off-White PowderMolecular weight:369.18748(S)-Silodosin
CAS:Formula:C25H32F3N3O4Color and Shape:White To Off-White SolidMolecular weight:495.541-(Mercaptomethyl)cyclopropaneacetic Acid
CAS:Controlled ProductApplications An intermediate of Montelukast. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormula:C6H10O2SColor and Shape:NeatMolecular weight:146.21Thioridazine Hydrochloride
CAS:Formula:C21H26N2S2·HClPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:407.033-Methyl-quinoxaline-2-carboxylic acid
CAS:Formula:C10H8N2O2Color and Shape:NeatMolecular weight:188.18Diclofenac EP Impurity C
CAS:Formula:C13H11Cl2NOColor and Shape:White To Off-White SolidMolecular weight:268.14(Z)-2-(((1-(2-Aminothiazol-4-yl)-2-((2-hydroxy-2-sulfoethyl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoic Acid
CAS:Controlled ProductFormula:C11H16N4O8S2Color and Shape:NeatMolecular weight:396.397Lasofoxifene Tartrate
CAS:Formula:C28H31NO2·C4H6O6Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:563.65(4R,cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:Controlled ProductApplications An impurity of Atorvastatin (A791750). References Jones, P., et al.: Am. J. Cardiol., 81, 582 (1998), Rosenson, R., et al.: Am. J. Med., 116, 408 (2004), Tiwari, A., et al.: Expert Opin. Drug Saf., 5, 651 (2006),Formula:C14H27NO4Color and Shape:NeatMolecular weight:273.37Ethametsulfuron
CAS:Formula:C14H16N6O6SColor and Shape:White To Off-White SolidMolecular weight:396.38Bexarotene
CAS:Formula:C24H28O2Purity:>96.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:348.493,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-,(3E,7E)-
CAS:Formula:C15H22OPurity:98%Color and Shape:SolidMolecular weight:218.33458N-[2-Chloro-3-(dimethylamino)-2-propen-1-ylidene]-N-methylmethanaminium Hexafluorophosphate
CAS:Formula:C7H14ClN2·F6PColor and Shape:White To Light YellowMolecular weight:306.62IEM 1754 2HBr
CAS:IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.Formula:C16H30N2·2HBrPurity:99.71% - 99.72%Color and Shape:SolidMolecular weight:412.25Candesartan Cilexetil Related Compound G (1-{[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylic acid)
CAS:Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFormula:C24H20N6O3Color and Shape:White PowderMolecular weight:440.15969Lasalocid A sodium 100 µg/mL in Acetonitrile
CAS:Formula:C34H53O8·NaColor and Shape:Single SolutionMolecular weight:612.77N-Nitroso Rac N-Desmethyl Tramadol
Formula:C15H22N2O3Color and Shape:Colourless To Light YellowMolecular weight:278.3471-Benzo[b]thien-4-yl-piperazine
CAS:Controlled ProductApplications is an intermediate in synthesizing Brexpiprazole 5-1H-Quinolin-2-one (B677428), an impurity of Brexpiprazole (B677385), which is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders. References Yamashita, H., et al.: PCT Int. Appl., WO 2006112464 A1 20061026 (2006)Formula:C12H14N2SColor and Shape:NeatMolecular weight:218.32Sodium 2-benzothiazolesulfonate
CAS:Stability Hygroscopic Applications Sodium 2-benzothiazolesulfonate is an organic pollutant found in soil. References Chamignon, C., et al.: Eur. J. Soil Sci., 59, 572 (2008)Formula:C7H5NO3S2·NaColor and Shape:White To Off-WhiteMolecular weight:238.2391-(Prop-2-yn-1-yl)-2,5-dihydro-1h-pyrrole-2,5-dione
CAS:Formula:C7H5NO2Purity:98%Color and Shape:SolidMolecular weight:135.120111-Oxo- Betamethasone 17,21 Dipropionate6β-Hydroxy Betamethasone 17,21 Dipropionate
Formula:C28H36F2O8Molecular weight:538.6
![(11b,16a,17a)-9-Chloro-17-(2,2-dioxido-5H-1,2-oxathiol-4-yl)-17-[(2-furanylcarbonyl)oxy]-11-hydrox…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC366515.webp&w=3840&q=75)
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![Candesartan Cilexetil Related Compound G (1-{[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxyb…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F45%2Fthumb-webp%2F1087870.webp&w=3840&q=75)
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