
Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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11-Oxo- Betamethasone 17,21 Dipropionate6β-Hydroxy Betamethasone 17,21 Dipropionate
Formula:C28H36F2O8Molecular weight:538.67-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one
CAS:Formula:C18H16O3Purity:97%Color and Shape:SolidMolecular weight:280.3178Ref: IN-DA003518
1g29.00€5g26.00€10g44.00€25g54.00€50g72.00€75g103.00€100g121.00€200g189.00€300g201.00€400g264.00€500g325.00€4-Dimethylamino Benzoic Acid-d6
CAS:Formula:C9H5D6NO2Color and Shape:White To Off-White SolidMolecular weight:171.23L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-
CAS:Formula:C8H15NO4SPurity:96%Color and Shape:SolidMolecular weight:221.274Tiotropium Bromide Impurity 22 Bromide
CAS:Formula:C19H22NO4S2·BrColor and Shape:White To Off-White SolidMolecular weight:392.51 79.90Gadoxetate Disodium Salt (Mixture of Diastereomers)
CAS:Formula:C23H28GdN3O11·2NaColor and Shape:White To Off-White SolidMolecular weight:679.74 2*22.99Spectinomycin dihydrochloride pentahydrate
CAS:Controlled ProductFormula:C14H24N2O7ClHH2OColor and Shape:NeatMolecular weight:495.3478L-Tyrosine Ethyl Ester Hydrochloride
CAS:Formula:C11H15NO3·HClPurity:>98.0%(T)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:245.70Valganciclovir-d5 DiHCl (Mixture of Diastereomers)
CAS:Formula:C14H17D5N6O5·2HClMolecular weight:359.40 2*36.46N-Boc-piperazine-d8
CAS:Controlled ProductApplications N-Boc-piperazine-d8 is a useful synthetic intermediate for the preparation of labelled compounds.Formula:C92H8H10N2O2Color and Shape:Light YellowMolecular weight:194.30N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine
CAS:Formula:C20H21NO4SPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:371.45N-Nitrosodiethylamine
CAS:Controlled ProductApplications N-Nitrosodiethylamine (DEN) is a widely occurring nitrosamine that is one of the most important environmental carcinogens (1) primarily inducing tumors of liver (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.NDMA and NDEA were found as an impurity in generic versions of valsartan, losartan and irbesartan. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References 1. Farber, E. et al.: Cancer Res. 1984 Oct;44(10):4217-23.2. el-Demerdash, E. et al.: Anticancer Res. 2002 Mar-Apr;22(2A):977-84.3. Kweon, S. et al.: Life Sci. 2003 Sep 26;73(19):2515-26.Formula:C4H10N2OColor and Shape:YellowMolecular weight:102.14Leflunomide Impurity 3
CAS:Formula:C12H9F3N2O2Color and Shape:White To Off-White SolidMolecular weight:270.212,4-Difluoro-a-(1H-1,2,4-triazolyl)acetophenone
CAS:Controlled ProductImpurity Voriconazole EP Impurity A; Voriconazole USP Related Compound C Applications 2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (Voriconazole EP Impurity A; Voriconazole USP Related Compound C) is an antifungal activity, particularly toward Candida albicans and Candida parapsilosis References Upadhayaya, R., et al.: Eur. J. Med. Chem., 39, 579 (2004), Sheng, C., et al.: J. Med. Chem., 49, 2512 (2006),Formula:C10H7F2N3OColor and Shape:BeigeMolecular weight:223.18Methocarbamol-d5
CAS:Formula:C11H10D5NO5Color and Shape:White To Off-White SolidMolecular weight:246.272-(3-Benzoylphenyl)propionic acid
CAS:Formula:C16H14O3Purity:98%Color and Shape:SolidMolecular weight:254.2806Naphthalen-1-yl-(1H-Pyrrol-3-yl)methanone
CAS:Formula:C15H11NOColor and Shape:White To Off-White SolidMolecular weight:221.263’-(3-Fluorophenyl) Ezetimibe
Controlled ProductFormula:C24H21F2NO3Color and Shape:NeatMolecular weight:409.425(13S,14S,17R)-Ethinyl Estradiol
CAS:Formula:C20H20O2Color and Shape:Yellow SolidMolecular weight:292.38Dabigatran Acyl-O-3-D-Glucuronide Trifluoroacetic Acid Salt
Formula:C31H33N7O9·CF3CO2HMolecular weight:647.65 114.02rac-Tenofovir Disoproxil Related Compound G Fumarate
Formula:C17H28N5O7PC4H4O4Molecular weight:445.42 116.07Memantine-Glucose Adduct
Controlled ProductFormula:C18H31NO5Color and Shape:NeatMolecular weight:341.44217α-Dihydro Equilenin 3-Sulfate Sodium Salt
CAS:Formula:C18H19O5S·NaColor and Shape:Off-White SolidMolecular weight:347.41 22.99(|S|)-Ethyl piperidine-3-carboxylate
CAS:Formula:C8H15NO2Purity:98%Color and Shape:LiquidMolecular weight:157.2102N-Desmethyl Dapoxetine HCl
CAS:Formula:C20H21NO·HClColor and Shape:White To Off-White SolidMolecular weight:291.40 36.461-Cyclopropyl-6-fluoro-1,4-dihydro-7-ethoxy-8-methoxy-4-oxo-3-quinolinecarboxylic Acid
CAS:Controlled ProductApplications 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-ethoxy-8-methoxy-4-oxo-3-quinolinecarboxylic Acid is used in the synthesis of new tetracyclic quinolone antibacterials. References Taguchi, M. et al.: J. Med. Chem., 35, 94 (1992);Formula:C16H16FNO5Color and Shape:White To Light YellowMolecular weight:321.37-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide-d6
CAS:Controlled ProductApplications Isotope labelled 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator. References Rodgers, T. et al.: J. Med. Chem., 20, 591 (1977); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);Formula:C19D6H16NO4S2Color and Shape:Off-WhiteMolecular weight:398.549(3R,4'S)-Benidipine HCl
CAS:Formula:C28H31N3O6·HClColor and Shape:Yellow SolidMolecular weight:505.58 36.46N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
CAS:Formula:C13H18N2O5SPurity:98%Color and Shape:SolidMolecular weight:314.35741,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane [Hydroxyl Protecting Agent]
CAS:Formula:C12H28Cl2OSi2Purity:>97.0%(GC)Color and Shape:Colorless to Almost colorless clear liquidMolecular weight:315.43Ciprofloxacin Hydrochloride Monohydrate
CAS:Formula:C17H18FN3O3·HCl·H2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:385.83Imidazole
CAS:Impurity Ondansetron EP Impurity E / Clotrimazole EP Impurity D Applications Imidazole (Ondansetron EP Impurity E) is a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals such as copper. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Arispe, N. et al.: Biophys. J., 95, 4879 (2008); Troesken, E.R. et al.: Endo. Res., 30, 387 (2004); Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2009);Formula:C3H4N2Color and Shape:Off WhiteMolecular weight:68.08Methyl DL-2-Aminobutyrate Hydrochloride
CAS:Formula:C5H11NO2·HClPurity:>98.0%(N)Color and Shape:White to Almost white powder to lumpMolecular weight:153.612,4,6-Tris(trifluoromethyl)benzamide
CAS:Controlled ProductApplications 2,4,6-Tris(trifluoromethyl)benzamide is an intermediate in the synthesis of 2,4,6-Tris(trifluoromethyl)aniline (T876695). 2,4,6-Tris(trifluoromethyl)aniline, is a Fluorinated substituents that have become valuable tool in medical chemistry. It can also be used for the preparation of azo dyes containing fluorine. References Gandel'sman, L. Z., et al.: Ukrainskii Khimicheskii , 41, 61 (1975); Edelbach, B. L., et al.: Synthesis, 44, 3595 (2012)Formula:C10H4F9NOColor and Shape:NeatMolecular weight:325.13Loratadine Related Compound A (8-Chloro-5,6-dihydro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C19H19ClN2Color and Shape:White Off-White Crystalline PowderMolecular weight:310.12368Pravastatin Sodium
CAS:Formula:C23H35NaO7Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:446.52Triclosan Methyl-d3 Ether
CAS:Controlled ProductApplications A bactericide detected in rivers and lakes. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lindstrom, A., et al.: Environ. Sci. Technol., 36, 2322 (2002)Formula:C132H3H6Cl3O2Color and Shape:NeatMolecular weight:306.59Argatroban Impurity 94
Formula:C13H15NO5SColor and Shape:White To Off-White SolidMolecular weight:297.331,2-Dibromo-4-(1,2-dibromoethyl)cyclohexane
CAS:Controlled ProductApplications Tetrabromoethylcyclohexane (TBECH) is an additive brominated flame retardant used in domestic and industrial applications. It was used to investigate the biodegradation kinetics in aerobic and anaerobic soil. References Ahn, M., et al.: Environ. Sci. Tech., 40, 215 (2006), Nyholm, J., et al.: Environ. Toxicol. Chem., 28, 1035 (2009),Formula:C8H12Br4Color and Shape:NeatMolecular weight:427.80Travoprost USP Related Compound A (Travoprost Acid)
CAS:Formula:C23H29F3O6Color and Shape:Colorless LiquidMolecular weight:458.47Vilanterol Trifenatate
CAS:Formula:C24H33Cl2NO5·C20H16O2Color and Shape:White To Off-White SolidMolecular weight:486.43 288.354-Hydroxybenzenepropanoic Acid
CAS:Formula:C9H10O3Color and Shape:White To Off-White SolidMolecular weight:166.18Gatifloxacin Related Compound A (1-Cyclopropyl-6-fluoro-8-hydroxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid)
CAS:Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoiFormula:C18H20FN3O4Color and Shape:Yellow SolidMolecular weight:361.14378Labetalol 1-Carboxylic Acid Hydrochloride
CAS:Controlled ProductFormula:C19H23NO4·ClHColor and Shape:NeatMolecular weight:365.854,4'-Dimethoxytrityl chloride
CAS:Formula:C21H19ClO2Purity:98%Color and Shape:SolidMolecular weight:338.8274Ref: IN-DA0033UZ
5g21.00€10g25.00€1kg206.00€25g25.00€50g33.00€5kgTo inquire100g56.00€10kgTo inquire250g77.00€500g111.00€50kgTo inquireRef: 4Z-P-398054
Discontinued productDi(2-Ethylhexyl) Azelate-d14
CAS:Formula:C25H34D14O4Color and Shape:Pale Yellow LiquidMolecular weight:426.74Rufloxacin HCl
CAS:Formula:C17H18FN3O3S·HClColor and Shape:Pale Yellow SolidMolecular weight:363.41 36.467-Demethyl Ivabradine Hydrochloride
CAS:Controlled ProductApplications Ivabradine (I940500) metabolite. References Duffull, S., et al.: Eur. J. Pharm. Sci., 10, 285 (2000), Portoles, A., et al.: J. Clin. Pharmacol., 46, 1195 (2006),Formula:C26H34N2O5·HClColor and Shape:NeatMolecular weight:491.02Gemcitabine
CAS:Formula:C9H11F2N3O4Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:263.20Bis(2-ethylhexyl)maleate (Maleic acid, bis(2-ethylhexyl)ester)
CAS:Maleic acid not in us note 3 section 6Formula:C20H36O4Color and Shape:LiquidMolecular weight:340.51