Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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N-(tert-Butoxycarbonyl)-L-tert-leucine
CAS:Formula:C11H21NO4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:231.29threo-Dihydro Bupropion Hydrochloride
CAS:Controlled ProductStability Hygroscopic Applications rac-threo-Dihydro Bupropion Hydrochloride is a metabolite of Bupropion (B689625), a selective inhibitor of dopamine uptake. References Suckow, R., et al.: Drug Metab Dispos., 14, 692 (1986);Formula:C13H20ClNO·HClColor and Shape:NeatMolecular weight:241.763646Argatroban Impurity 24 (Mixture of Diastereomers)
Formula:C23H36N6O5SColor and Shape:White To Off-White SolidMolecular weight:508.64Daunorubicin HCl
CAS:Formula:C27H29NO10·HClColor and Shape:Orange Red SolidMolecular weight:527.53 36.46(22S)-Budesonide
CAS:Controlled ProductApplications Budesonide (B689490) epimer S. Budesonide 22R epimer is more active than 22S epimer. Used as an antiinflammatory agent. References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),Formula:C25H34O6Color and Shape:NeatMolecular weight:430.53(R)-cis-5ξ-Methyl Atracurium Dibesylate
CAS:Formula:C54H74N2O12(C6H5O3S)Molecular weight:943.2 : 2(157.2)Chloroxuron-d6
CAS:Formula:C15H9D6ClN2O2Color and Shape:White To Off-White SolidMolecular weight:296.787-(Desacetothioxy)-7-acetodithioperoxy-spironolactone
Controlled ProductFormula:C24H32O4S2Color and Shape:NeatMolecular weight:448.64Oxacillin Sodium Salt Monohydrate
CAS:Formula:C19H18N3NaO5S·H2OPurity:>95.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:441.44Apomorphine-8-Sulfonic Acid
CAS:Controlled ProductApplications Apomorphine-8-Sulfonic Acid is an impurity of (R)-(-)-Apomorphine(A727495), (R)-(-)-Apomorphine is a dopamine (D1 and D2) receptor agonist. Emetic. Antiparkinsonian. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Neumeyer, J.L., et al.: J. Pharm. Sci., 59, 1850 (1970); Ginos, J.Z., et al.: J. Med. Chem., 18, 1194 (1975); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 20, 121 (1991)Formula:C17H17NO5SColor and Shape:NeatMolecular weight:347.386N-Propargyltrifluoroacetamide
CAS:Formula:C5H4F3NOPurity:min. 98.0 %(GC)Color and Shape:Colorless to Light yellow to Light orange clear liquidMolecular weight:151.09Haloperidol Decanoate HCl
CAS:Formula:C31H41ClFNO3·HClColor and Shape:White To Off-White SolidMolecular weight:530.12 36.46Methocarbamol
CAS:Formula:C11H15NO5Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:241.24Tolterodine N-oxide, >90%
CAS:Controlled ProductStability Temperature Sensitive Applications Tolterodine N-oxide is an impurity of Tolterodine (T535800), a muscarinic receptor antagonist used in the treatment of urinary incontinence. References Nilvebrant, L., et al.: Life Sci., 60, 1129 (1997), Nilvebrant, L., et al.: Eur. J. Pharmacol., 327, 195 (1997), Brynne, N., et al.: Int. J. Clin. Pharmacol. Ther., 35, 287 (1997)Formula:C22H31NO2Purity:>90%Color and Shape:NeatMolecular weight:341.487Torasemide (Torsemide)
CAS:Formula:C16H20N4O3SColor and Shape:White To Off-White SolidMolecular weight:348.43Idelalisib Metabolite (GS-563117)
Formula:C22H18FN7O2Color and Shape:White To Off-White SolidMolecular weight:431.43Phenylalanine, N-benzoyl-
CAS:Formula:C16H15NO3Purity:97%Color and Shape:SolidMolecular weight:269.2952Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt
Controlled ProductStability Unstable in Solution Applications Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt is labeled form of Desphenyl Tenofovir Alafenamide (D297043), which belongs to a group of tenofovir diesters compounds, which can inhibit HIV-1 virus replication. Desphenyl Tenofovir Alafenamide can also be used to investigate the effect of oral absorption and lymphoid cell loading of GS-7340 (a prodrug of tenofovir) References You, G., et al.: PCT Int. Appl. WO 2014026582 A1 2014022 (2014); Babusis, D., et al.: Mol. Pharm. 10, 459 (2013)Formula:C15H21D7N7O5PColor and Shape:NeatMolecular weight:424.44Rivaroxaban Impurity 113
CAS:Formula:C23H21Cl2N3O5S2Color and Shape:Off-White SolidMolecular weight:554.46Triamcinolone Acetonide Related Compound B (9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-(11β,16α)-pregna-1,4,14-triene-3,20-dione)
CAS:Halogenated, sulfonated, nitrated or nitrosated derivatives of ketoneFormula:C24H29FO6Color and Shape:PowderMolecular weight:432.19482N-Formyl-D-phenylalanine
CAS:Formula:C10H11NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:193.20Cinnamylamine Hydrochloride
CAS:Applications Cinnamylamine Hydrochloride, can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. References Stout, S.C., et al.: J. Pharmacol. Exp. Ther., 300, 1085 (2002), Yoshida, S. et al.: Bioorg. Med. Chem., 12, 2645 (2004);Formula:C9H11N·ClHColor and Shape:NeatMolecular weight:169.65Roflumilast-d4 N-Oxide
CAS:Formula:C17H10D4Cl2F2N2O4Color and Shape:White To Off-White SolidMolecular weight:423.23Hexakis(2,2-difluoroethoxy)phosphazene
CAS:Controlled ProductApplications Hexakis(2,2-difluoroethoxy)phosphazene can be used as an ion source in studying ion traps. References Hilger, Ryan T., et al.: Inter. J. of Mass Spec., 377, 329-337 (2015)Formula:C12H18F12N3O6P3Color and Shape:Off-White To Light BrownMolecular weight:621.193,4-Diaminobenzoic acid
CAS:Formula:C7H8N2O2Purity:97%Color and Shape:SolidMolecular weight:152.150621-Naphthalenepropanoic acid, α-amino-, hydrochloride (1:1), (αS)-
CAS:Formula:C13H14ClNO2Purity:97%Color and Shape:SolidMolecular weight:251.7088Doxorubicinol-13C-d3 HCl (Mixture of Diasteromers)
CAS:Formula:CC26H28NO11D3Molecular weight:549.58 36.46Methane-13C-sulfonate Sodium (contains up to 15% inorganics)
CAS:Controlled ProductFormula:CH3NaO3SColor and Shape:White To Off-WhiteMolecular weight:119.08N-Nitrosodiethylamine (100ug/mL in Methanol)
CAS:Controlled ProductFormula:C4H10N2OColor and Shape:Single SolutionMolecular weight:102.14Kirenol
CAS:Formula:C20H34O4Purity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:338.49L-Serine, N-(2,4-dinitrophenyl)-
CAS:Formula:C9H9N3O7Purity:98%Color and Shape:SolidMolecular weight:271.1837Metformin
CAS:Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formula:C4H11N5Purity:100% - 99.78Color and Shape:SolidMolecular weight:129.16Tiotropium Bromide Impurity 13
Formula:C14H10O2S3Color and Shape:Off-White SolidMolecular weight:306.413,3',5-Triiodo Thyroacetic Acid-13C6
CAS:Controlled ProductApplications 3,3',5-Triiodo Thyroacetic Acid-13C6 is the labelled version of 3,3',5-Triiodo Thyroacetic Acid (795320) which is Thyroid hormone analogue. A potent Thyroxine impurity. References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),Formula:C6C8H9I3O4Color and Shape:NeatMolecular weight:627.888Benzyl [[[2-[(2,6-Dichlorophenyl)amino]phenyl]acetyl]oxy]acetate (Benzyl Ester of Aceclofenac)
CAS:Formula:C23H19Cl2NO44-Benzyloxyphenyl 4-Hydroxyphenyl Sulfone
CAS:Applications 4-Benzyloxyphenyl 4-Hydroxyphenyl Sulfone is used in the synthesis of Bis(4-hydroxyphenyl) Sulfone O-β-D-Glucuronide (B447395), which is a compound that is commonly used as a reactant in epoxy reactions. It is also used as a latent thermal catalyst for epoxy resin. References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012)Formula:C19H16O4SColor and Shape:NeatMolecular weight:340.39Sodium 1-[(9H-Fluoren-9-ylmethoxy)carbonylamino]cyclopropanecarboxylate
CAS:Formula:C19H16NNaO4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:345.33Iopromide Impurity 40 (Mixture of Diastereomers)
Formula:C33H39I6N5O14Color and Shape:White To Off-White SolidMolecular weight:1491.124,4,4-Tris(benzoyloxy)trityl Bromide [Hydroxyl Protecting Agent]
CAS:Formula:C40H27BrO6Purity:95%Color and Shape:SolidMolecular weight:683.5428Dienogest
CAS:Formula:C20H25NO2Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:311.431-Ethynyl-4-hexylbenzene
CAS:Formula:C14H18Purity:95%Color and Shape:LiquidMolecular weight:186.29272
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