Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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Quetiapine Related Compound H (4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-[2-(2-hydroxyethoxy)ethyl]piperazine 1-oxide)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C21H25N3O3SColor and Shape:PowderMolecular weight:399.161661-Ethynyl-4-hexylbenzene
CAS:Formula:C14H18Purity:95%Color and Shape:LiquidMolecular weight:186.29272Glycinamide Hydrochloride
CAS:Formula:C2H6N2O·HClPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:110.54Cyclobenzaprine-13C-d3 HCl
CAS:Formula:C19CH18D3N·HClColor and Shape:White To Off-White SolidMolecular weight:279.41 36.463’-(2-Fluorophenyl) Ezetimibe
CAS:Controlled ProductImpurity Ezetimibe o-Fluorobenzene Isomer (USP) Applications 3’-(2-Fluorophenyl) Ezetimibe is an impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and a cholesterol absorption inhibitor. References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)Formula:C24H21F2NO3Color and Shape:White To Off-WhiteMolecular weight:409.43Cholesterol 5a,6a-epsilonpoxide
CAS:Controlled ProductApplications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols. References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)Formula:C27H46O2Color and Shape:NeatMolecular weight:402.65rac cis-3-((tert-Butyldimethylsilyl)oxy)-1-(4-nitrophenyl)cyclopentanecarbonitrile
CAS:Controlled ProductFormula:C18H26N2O3SiColor and Shape:NeatMolecular weight:346.496(1S,3R)-3-[[(tert-Butoxy)carbonyl]amino]cyclohexanecarboxylic acid
CAS:Formula:C12H21NO4Purity:97%Color and Shape:SolidMolecular weight:243.2994Acepromazine hydrochloride
CAS:Controlled ProductFormula:C19H22N2OS·ClHColor and Shape:NeatMolecular weight:362.92N-Desmethyl Topotecan
CAS:Stability Unstable in Solution Applications A metabolite of Topotecan. References Herben, V., et al.: Anti-Cancer Drugs, 9, 411 (1998), Hsiang, Y., et al.: Cancer Res., 48, 1722 (1988), Hertzberg, R., et al.: J. Med. Chem., 32, 715 (1989), Beijnen, J., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990),Formula:C22H21N3O5Color and Shape:NeatMolecular weight:407.424-Deschloro-4-bromo Ospemifene
Controlled ProductApplications 4-Deschloro-4-bromo Ospemifene is an impurity of Ospemifene (O703000). Ospemifene is used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen. References Rutanen, E., et al.: Menopause, 10, 433 (2003)Formula:C24H23BrO2Color and Shape:NeatMolecular weight:423.3424,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
CAS:Formula:C15H10Cl2N4O2Purity:>98.0%(GC)(N)Color and Shape:White to Light yellow powder to crystalMolecular weight:349.172-Methyl-5-nitro-1-(2-oxiranylmethyl)-1H-imidazole
CAS:Controlled ProductApplications 2-Methyl-5-nitro-1-(2-oxiranylmethyl)-1H-imidazole is an impurity of Ornidazole (O688500) which has antifertility activity. References Jones, A., et al.: Xenobiotica, 27, 711 (1997); Cooper, T., et al.: J. Andrology, 18, 431 (1997)Formula:C7H9N3O3Color and Shape:NeatMolecular weight:183.16N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel
CAS:Formula:C46H55NO14Color and Shape:NeatMolecular weight:845.93Tenofovir Dibenzyloxy Isopropyl Carbamate
CAS:Controlled ProductApplications Protected Tenofovir (T018500). Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)Formula:C27H32N5O6PColor and Shape:NeatMolecular weight:553.55Methylamine HCl
CAS:Formula:CH5N·HClColor and Shape:White To Off-White SolidMolecular weight:31.06 36.46Propionylpromazine hydrochloride
CAS:Formula:C20H24N2OS·ClHColor and Shape:NeatMolecular weight:376.94N,N'-Disuccinimidyl carbonate
CAS:Formula:C9H8N2O7Purity:98%Color and Shape:SolidMolecular weight:256.169Heptobarbital (1mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C11H10N2O3Color and Shape:Single SolutionMolecular weight:218.211,2-Bis(maleimido)ethane
CAS:Formula:C10H8N2O4Purity:>98.0%(N)Color and Shape:White to Light yellow to Light red powder to crystalMolecular weight:220.18Tricyclo[3.3.1.13,7]decane-1-methanamine, α-methyl-, hydrochloride (1:1)
CAS:Formula:C12H22ClNPurity:97%Color and Shape:SolidMolecular weight:215.7628Etoricoxib N-Oxide 1
CAS:Formula:C18H15ClN2O3SColor and Shape:White To Off-White SolidMolecular weight:374.84N-Nitroso-Atomoxetine
Controlled ProductFormula:C17H20N2O2Color and Shape:Off WhiteMolecular weight:284.353(tert-Butoxycarbonyl)-D-histidine
CAS:Formula:C11H17N3O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:255.27Schisandrin A
CAS:Formula:C24H32O6Purity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:416.51Cephalomannine (Paclitaxel USP Related Compound A)
CAS:Formula:C45H53NO14Color and Shape:White To Off-White SolidMolecular weight:831.912-Piperidinecarboxylic acid, (2S)-
CAS:Formula:C6H11NO2Purity:97%Color and Shape:SolidMolecular weight:129.157Apomorphine-13C-d3 HCl
CAS:Formula:C1613CH14D3NO2·HClColor and Shape:Off-White SolidMolecular weight:271.34 36.461-Nitrosopyrrolidin-2-one
CAS:Controlled ProductFormula:C4H6N2O2Color and Shape:YellowMolecular weight:114.1Parthenolide
CAS:Formula:C15H20O3Purity:>97.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:248.32Dichloroacetaldehyde Hydrate
CAS:Applications A Dichloroethylene metabolite formed by human microsomes and is mediated by CYP2E1 in liver and in some individuals in lung. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Dowsley, T.F. et al.: J. Pharmac. Exp. Therap., 289, 641 (1999); Simmonds, A.C. et al.: Drug. Metab. and Dispos., 32, 1032 (2004);Formula:C2H2Cl2O·H2OColor and Shape:NeatMolecular weight:130.958Sulfamethoxazole D4 (benzene D4)
CAS:Controlled ProductFormula:C10H4H7N3O3SColor and Shape:NeatMolecular weight:257.30Mubritinib
CAS:Formula:C25H23F3N4O2Purity:>98.0%(HPLC)Color and Shape:White to Gray to Brown powder to crystalMolecular weight:468.48Pantoprazole Magnesium Salt
CAS:Formula:C32H28F4N6O8S2·MgColor and Shape:White To Off-White SolidMolecular weight:764.74 24.31Levetiracetam-D6
CAS:Controlled ProductApplications Levetiracetam-d6 is a labelled (S)-enantiomer of the ethyl analog of Piracetam (P500800), an anticonvulsant. References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992), Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996), Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000),Formula:C8D6H8N2O2Color and Shape:White To Light YellowMolecular weight:176.25Venlafaxine hydrochloride
CAS:Formula:C17H28ClNO2Purity:98%Color and Shape:SolidMolecular weight:313.86272000000013'-N-Desmethyl-3'-N-formyl Azithromycin
CAS:Impurity Azithromycin EP Impurity F / USP Azithromycin Related Compound F Stability Hygroscopic Applications Azithromycin impurity. References Kirst, H., et al.: Antimicrob. Agents Chemother., 33, 1419 (1989), Fouda, H., et al.: Ther. Drug Monit., 17, 179 (1995), Gandhi, R., et al.: J. Pharm. Biomed. Anal., 23, 1073 (2000),Formula:C38H70N2O13Color and Shape:NeatMolecular weight:762.974-Fluoro-D-phenylalanine
CAS:Formula:C9H10FNO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:183.18Betahistine DiHCl
CAS:Formula:C8H12N2·2HClColor and Shape:Pale Orange SolidMolecular weight:136.20 2*36.462,3-Dihydro-5,6-dimethoxy-2-[(4-piperidinyl)methyl]indan-1-one Hydrochloride
CAS:Formula:C17H23NO3·ClHTriethylene Glycol 2-Bromoethyl Methyl Ether
CAS:Formula:C9H19BrO4Purity:95%Color and Shape:LiquidMolecular weight:271.148760000000044-Bromoestrone (>90%)
CAS:Controlled ProductFormula:C18H21BrO2Purity:>90%Color and Shape:NeatMolecular weight:349.26Diclofenac Dodecyl Ester
Applications Diclofenac Dodecyl Ester is a Diclofenac impurity. Diclofenac is a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor. References Kretz-Rommel, A., et al.: Toxicol. Appl. Pharmacol., 120, 155 (1993), Petronilli, V., et al.: J. Biol. Chem., 269, 16638 (1994), Bort, R., et al.: J. Pharmacol. Exp. Ther., 288, 65 (1998), Poon, G., et al.: Drug Metab. Dispos., 29, 1608 (2001),Formula:C26H35Cl2NO2Color and Shape:NeatMolecular weight:464.47(24R)-Fungisterol ((24R)-δ-7-Campesterol)
CAS:Formula:C28H48OColor and Shape:White To Off-White SolidMolecular weight:400.69Benzoic acid, 4-amino-2-chloro-
CAS:Formula:C7H6ClNO2Purity:97%Color and Shape:SolidMolecular weight:171.581Amoxicillin Related Compound F (3-(4-Hydroxyphenyl)pyrazin-2-ol; phenylpyrazinediol)
CAS:Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoiFormula:C10H8N2O2Color and Shape:Yellow PowderMolecular weight:188.05858Ibutilide USP Related Compound B
CAS:Formula:C20H34N2O4SColor and Shape:Off-White SolidMolecular weight:398.56N-Succinimidyl S-Acetylthioglycolate [Cross-linking Reagent]
CAS:Formula:C8H9NO5SPurity:>94.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:231.22
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