Sulfonamides and Derivatives
Sulphonamides are compounds that contain a sulphonamide functional group (-SO₂NH₂), where a sulphur atom is bonded to an amino group. They were among the first synthetic antibiotics used in medicine, inhibiting folic acid synthesis in bacteria, which gives them antimicrobial properties. They are mainly used to treat bacterial infections, although their use has declined due to antimicrobial resistance. In addition to their use as antibiotics, sulphonamides also have applications in the treatment of diseases such as malaria and inflammatory bowel diseases.
At CymitQuimica, we offer high-purity sulphonamides and their derivatives for research in microbiology and pharmaceutical development.
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3-Chloro-4-hydroxyacetanilide
CAS:3-Chloro-4-hydroxyacetanilide is a chemical compound that belongs to the class of acetanilides. It has long-term toxicity and is used as a drug substance in the production of aniline derivatives. 3-Chloro-4-hydroxyacetanilide has been shown to be carcinogenic in hamsters. The long term exposure to this chemical was shown to cause liver damage and increased incidence of tumours in rats. This drug also contains impurities and traces of chloride, chlorine, and thionyl chloride, which are toxic substances that can cause irritation or burns on contact with skin or eyes.Formula:C8H8ClNO2Purity:Min. 95%Molecular weight:185.61 g/molTorasemide (Torsemide) Impurity 4
CAS:Formula:C16H20N4O3SColor and Shape:White To Off-White SolidMolecular weight:348.42Sulfamethoxazole
CAS:Sulfamethoxazole (STX 608), a sulfonamide antimicrobial, inhibits Cytochrome P450 2C9.Formula:C10H11N3O3SPurity:99.71%Color and Shape:Crystals Or White PowderMolecular weight:253.285-Chloro Hydrochlorothiazide
CAS:Formula:C7H7Cl2N3O4S2Color and Shape:White To Off-White SolidMolecular weight:332.17Sulfamethoxazole sodium
CAS:Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibioticFormula:C10H10N3NaO3SPurity:99.13% - 99.43%Color and Shape:SolidMolecular weight:275.26Piroxicam EP Impurity A
CAS:Formula:C5H6N2Color and Shape:White To Off-White SolidMolecular weight:94.12Chlortalidone (Chlorthalidone) EP Impurity D
CAS:Formula:C16H15ClN2O4SColor and Shape:White To Off-White SolidMolecular weight:366.823-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid
CAS:3-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid is a chemical compound that is an impurity standard for HPLC. It is also used as a pharmacopoeia, drug development, and analytical reference standard. The CAS number for this compound is 66364-71-4. This compound has been shown to be metabolized by microsomal oxidation, glucuronidation, or sulfation pathways in humans. 3-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid can also be found in natural sources such as plants and animals.Formula:C18H14N4O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:398.39 g/molIbuprofen EP Impurity F
CAS:Controlled ProductFormula:C13H18O2Color and Shape:NeatMolecular weight:206.28Dorzolamide Impurity 14
Formula:C12H17NO6S3Color and Shape:White To Off-White SolidMolecular weight:367.45Sulfadimethoxine
CAS:Sulfadimethoxine (Sulphadimethoxine) is a sulfanilamide that is used as an anti-infective agent.Formula:C12H14N4O4SPurity:99.30%Color and Shape:Yellow To Straw Yellow PowderMolecular weight:310.33Acetazolamide Impurity - N-(5-Acetamido-1,3,4-Thiadiazole-2-YL) Sulphamoyl-1,3,4-Thiadiazol-2-yl Acetamide
Formula:C8H9N7O4S3Molecular weight:363.40Glipizide Impurity 1 HCl
CAS:Formula:C15H23N3O3S·HClColor and Shape:White To Off-White SolidMolecular weight:325.43 36.46Bromfenac
CAS:Bromfenac, a potent COX inhibitor, targets ocular inflammation with IC50s of 5.56 nM for COX-1 and 7.45 nM for COX-2.Formula:C15H12BrNO3Color and Shape:SolidMolecular weight:334.16Bumetanide Impurity 1 (Bumetanide Propyl Analogue)
CAS:Formula:C16H18N2O5SColor and Shape:White To Off-White SolidMolecular weight:350.39Furosemide EP Impurity B
CAS:Formula:C7H5Cl2NO4SColor and Shape:White To Off-White SolidMolecular weight:270.084-Carboxy Tolbutamide-d9
CAS:Controlled ProductStability Hygroscopic Applications A labelled metabolite of Tolbutamide. Formed by the cytochrome CYP2CIIC8 and IIC9 subfamily of P450 enzymes. References Relling, etl al.: J. Pharmacol. Exp. Ther., 252, 442 (1990), Parent, et al.: J. Pharmacol. Exp. Ther., 261, 780 (1992), Ho, et al.: Life Sci., 52, 21 (1993),Formula:C12D9H7N2O5SColor and Shape:NeatMolecular weight:309.393-Ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
CAS:Color and Shape:Neat4-[(1,4-Diazepan-1-yl)sulfonyl]morpholine
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:249.3300018310547Dorzolamide Impurity 2 Sodium Salt
CAS:Formula:C20H28N3O8S6·NaColor and Shape:White To Off-White SolidMolecular weight:630.82 22.99N,N-Dimethyl Zonisamide (Zonisamide USP Related Compound C (Mixture of Isomers))
CAS:Formula:C11H13N3O3SMolecular weight:267.31Ibuprofen Impurity 12
CAS:Formula:C21H27NOColor and Shape:White To Off-White SolidMolecular weight:309.45Hydrochlorothiazide-13C-d2
CAS:Formula:C613CH6D2ClN3O4S2Color and Shape:White To Off-White SolidMolecular weight:300.73Metamizole EP Impurity C HCl
CAS:Formula:C12H15N3O·HClColor and Shape:Off-White SolidMolecular weight:217.27 36.46(E)-N-(5-(benzylthio)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene) Acetamide
CAS:Formula:C12H13N3OS2Molecular weight:279.38Torasemide Impurity E
CAS:Torasemide Impurity E is a drug product that belongs to the group of impurities. It is a natural product and can be found in the environment. Torasemide Impurity E has been shown to inhibit bacterial growth in vitro and also antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus. Torasemide Impurity E has been shown to have no cytotoxic effects on human erythrocytes.Formula:C15H17N3O4SPurity:Min. 95%Molecular weight:335.38 g/molSulfadiMethoxine sodium
CAS:Sulfadimethoxine is a antimicrobial agent, treatment of respiratory, urinary tract, enteric, and soft tissue infectionsFormula:C12H13N4NaO4SPurity:99.53%Color and Shape:White Or Straw Yellow PowderMolecular weight:332.31Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494Aceclofenac EP Impurity C
CAS:Formula:C16H15Cl2NO2Color and Shape:White To Off-White SolidMolecular weight:324.20Indomethacin Impurity 6
CAS:Formula:C11H11NO3Color and Shape:Pale Yellow SolidMolecular weight:205.214-Chloro-3-sulfamoylbenzoic Acid
CAS:Controlled ProductFormula:C7H6ClNO4SColor and Shape:NeatMolecular weight:235.64Indomethacin Impurity 17
Formula:C10H11ClO3Color and Shape:White To Off-White SolidMolecular weight:214.652-(4-Isobutylphenyl)propionitrile
CAS:Controlled ProductFormula:C13H17NColor and Shape:NeatMolecular weight:187.28Amtolmetin guacil
CAS:Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性,具有额外的镇痛、解热和胃保护特性。Formula:C24H24N2O5Purity:99.63%Color and Shape:White Needle-Shaped CrystalMolecular weight:420.46Trimethoprim EP Impurity D
CAS:Formula:C14H17N3O4Color and Shape:Off-White SolidMolecular weight:291.312-Amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-4-ol
CAS:Controlled ProductFormula:C14H17N3O4Color and Shape:NeatMolecular weight:291.30Metazachlor Impurity 3
CAS:Formula:C3H3ClO2Color and Shape:White To Off-White SolidMolecular weight:106.51Paracetamol EP Impurity A (Acetaminophen USP Related Compound C)
CAS:Formula:C8H9NO2Color and Shape:Brown SolidMolecular weight:151.17Sulfadimethoxine EP Impurity E
CAS:Formula:C6H8N2O2SColor and Shape:White To Off-White SolidMolecular weight:172.20Sulfasalazine EP Impurity E Trisodium Salt
CAS:Formula:C29H19N6O7S2·3NaMolecular weight:627.63 3*22.99Altizide
CAS:Altizide is a thiazide diuretic. It is used to treat oedema and hypertension.Formula:C11H14ClN3O4S3Purity:98%Color and Shape:SolidMolecular weight:383.893-Cysteinyl Acetaminophen HCl
CAS:Formula:C11H14N2O4S·HClColor and Shape:White To Off-White SolidMolecular weight:270.31 36.46Pyroxasulfone
CAS:Pyroxasulfone stops fatty acid growth, controls pre-emergence grass weeds in crops.Formula:C12H14F5N3O4SColor and Shape:SolidMolecular weight:391.31Acetazolamide EP Impurity G
CAS:Formula:C2H3N3S2Color and Shape:Pale Yellow SolidMolecular weight:133.19Mesotrione
CAS:Mesotrione is a selective triketone herbicideFormula:C14H13NO7SPurity:99.39%Color and Shape:Light Yellow Crystalline PowderMolecular weight:339.32Saflufenacil Impurity 1
CAS:Formula:C16H15ClF4N4O5SColor and Shape:White To Off-White SolidMolecular weight:486.82Ethyl [(4-Methylphenyl)sulphonyl]carbamate
CAS:Controlled ProductFormula:C10H13NO4SColor and Shape:NeatMolecular weight:243.28N-[[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester
CAS:Applications N-[[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester, is an impurity of Glimepiride (G410150), which is a medium- to long-acting sulfonylurea antidiabetic drug. References Ratheiser, K., et al.: Arzneim.-Forsch., 43, 856, (1993);Formula:C18H23N3O6SColor and Shape:White To Off-WhiteMolecular weight:409.46Dorzolamide Impurity 6 DiHCl
Formula:C20H29N3O8S6·2HClColor and Shape:White To Off-White SolidMolecular weight:631.85 2*36.46Bumetanide Impurity 9 HCl
Formula:C11H16N2O5S·HClColor and Shape:Off-White SolidMolecular weight:288.32 36.46Piroxicam EP Impurity D
CAS:Formula:C10H9NO5SColor and Shape:White To Off-White SolidMolecular weight:255.24Sulfasalazine EP Impurity I Sodium Salt
CAS:Formula:C13H9N2O6S·NaColor and Shape:Orange SolidMolecular weight:321.29 22.99rac-Ibuprofen amide
CAS:Ibuprofen amide is a nonsteroidal anti-inflammatory drug that belongs to the class of amides. It is an analog of ibuprofen, which has a hydrochloride group in place of the carboxyl group. Ibuprofen amide inhibits the production of pro-inflammatory chemicals by blocking cyclooxygenase enzymes, which are responsible for synthesis of prostaglandins and thromboxanes. The kinetic profile of this compound was obtained using fluorescence spectroscopy. This analytical method also showed that ibuprofen amide hydrolyzes in acidic conditions, suggesting that it may be active against bacteria that are found in an acidic environment.Formula:C13H19NOPurity:Min. 98 Area-%Molecular weight:205.3 g/molIbuprofen 1,2-Propylene Glycol Esters (Mixture of Regio- and Stereoisomers)
Controlled ProductFormula:C16H24O3Color and Shape:MixtureMolecular weight:528.72Glipizide Impurity 27
Formula:C36H46N8O8S2Color and Shape:White To Off-White SolidMolecular weight:782.93N,N-Bis(methylsulphonyl)-2-phenoxyaniline
CAS:Controlled ProductFormula:C14H15NO5S2Color and Shape:NeatMolecular weight:341.40Indomethacin Impurity 4 HCl
CAS:Formula:C7H10N2O·HClColor and Shape:White To Off-White SolidMolecular weight:138.17 36.46Indomethacin Impurity 11
CAS:Formula:C10H11ClO4Color and Shape:White To Off-White SolidMolecular weight:230.64Aceclofenac EP Impurity G
CAS:Formula:C18H15Cl2NO6Color and Shape:White To Off-White SolidMolecular weight:412.23Ibuprofen EP Impurity C
CAS:Formula:C13H19NOColor and Shape:White To Off-White SolidMolecular weight:205.30Flufenamic Acid Ethyl Ester
CAS:Controlled ProductFormula:C16H14F3NO2Color and Shape:NeatMolecular weight:309.28Paracetamol EP Impurity E
CAS:Formula:C8H8O2Color and Shape:White To Off-White SolidMolecular weight:136.15Furosemide EP Impurity C (Furosemide USP Related Compound B)
CAS:Formula:C7H7ClN2O4SColor and Shape:White To Off-White SolidMolecular weight:250.65Sulfamethoxazole Impurity 2
CAS:Formula:C10H11N3O3SColor and Shape:Off-White SolidMolecular weight:253.28Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Minute Brownish-Yellow CrystalsMolecular weight:398.39Indomethacin
CAS:Indomethacin (Indomethacin) is a inhibitor of COX1 and COX2. Indomethacin is a non-steroidal anti-inflammatory agent. Cost-effective and quality-assured.Formula:C19H16ClNO4Purity:99.27% - 99.76%Color and Shape:Pale-Yellow To Yellow-Tan Crystalline Powder Physical Description Crystals (Ntp 1992)Molecular weight:357.79Sulfadimethoxine Sodium Salt
CAS:Formula:C12H13N4O4S·NaColor and Shape:White To Off-White SolidMolecular weight:309.32 22.99(2-Ethoxy-2-oxoethyl) 2-(5-Methoxy-2-methyl-1H-indol-3-yl)acetate
Formula:C16H19NO5Color and Shape:Neat(2,4-Diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanone
CAS:Controlled ProductFormula:C14H16N4O4Color and Shape:NeatMolecular weight:304.30Trimethoprim
CAS:Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.Formula:C14H18N4O3Purity:99.80% - 99.81%Color and Shape:White To Yellowish PowderMolecular weight:290.32Furosemide Impurity 30-d3 (4-Chloro-2-Fluorobenzoic Acid-d3)
CAS:Formula:C7HD3ClFO2Molecular weight:177.57Dorzolamide Impurity 16
Formula:C10H14N2O5S3Color and Shape:White To Off-White SolidMolecular weight:338.41Ibuprofen EP Impurity M
CAS:Formula:C13H18O3Color and Shape:White To Off-White SolidMolecular weight:222.28(3RS)-1,3-Bis[4-(2-methylpropyl)phenyl]butan-1-one
CAS:Controlled ProductFormula:C24H32OColor and Shape:NeatMolecular weight:336.51Acetazolamide EP Impurity A
CAS:Formula:C4H4ClN3OSColor and Shape:White To Off-White SolidMolecular weight:177.612-[4-(2-Methylpropanoyl)phenyl] propanoic acid
CAS:2-[4-(2-Methylpropanoyl)phenyl] propanoic acid is a pharmaceutical intermediate that is used for the production of carprofen. It has been found to be an analytical method for the determination of 4-hydroxybenzoic acid and 4-isobutylacetophenone. The compound is analyzed by chromatographic methods and electrophoresis methods. The optimization of the solvent composition, flow rate, and impurities during the synthesis process are also studied in this research. 2-[4-(2-Methylpropanoyl)phenyl] propanoic acid has been found to be a meaningful validation of analytical methods for medicines, with an impurity limit of 0.1%.Formula:C13H16O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:220.26 g/molTolbutamide-d9
CAS:Formula:C12H9D9N2O3SColor and Shape:White To Off-White SolidMolecular weight:279.40Metamizole Impurity 5
CAS:Formula:C25H30N6O2Color and Shape:White To Off-White SolidMolecular weight:446.56Aceclofenac methyl ester
CAS:Aceclofenac methyl ester is an analgesic that belongs to the arylpropionic acid derivatives. It has been developed for the treatment of acute pain. Aceclofenac methyl ester has a structural formula of CH3CO-O-CH3 and a molecular weight of 164.2 g/mol. Aceclofenac is metabolized by CYP450 enzymes, which are located in the liver and other organs, to form acetic acid and 5-hydroxyaceclofenac. The reaction time is approximately 1 hour and tetrahydrofuranyl (THF) is used as a nucleophile in this reaction. This product can be synthesized by reacting ethyl acetate with acetonitrile in high yield, making it stable and anhydrous. The analgesic effects of aceclofenac methyl ester are due to its ability to block the transmission of pain signals from nerves to the brain at the spinal cord levelFormula:C17H15Cl2NO4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:368.21 g/molDorzolamide Impurity 2 DiHCl
Formula:C20H29N3O8S6·2HClColor and Shape:White To Off-White SolidMolecular weight:631.85 2 36.461-(2-Methylpropyl)-4-[(3RS)-3-[4-(2-methylpropyl)phenyl]butyl]benzene
CAS:Controlled ProductFormula:C24H34Color and Shape:NeatMolecular weight:322.534-Carboxy Tolbutamide
CAS:Controlled ProductFormula:C12H16N2O5SColor and Shape:NeatMolecular weight:300.33Trimethoprim 3-oxide
CAS:Trimethoprim 3-oxide trimethoprim primary metabolite.Formula:C14H18N4O4Purity:98%Color and Shape:SolidMolecular weight:306.32
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