Sulfonamides and Derivatives

Sulfadiazine, a short-acting sulfonamide, blocks bacterial folic acid synthesis; used with pyrimethamine to treat toxoplasmosis in AIDS, newborns.

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)

Bromisoval (Isobromyl) is a mild hypnotic and sedative with potential toxicity.

Applications Bis(4-hydroxyphenyl) Sulfone is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin. References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012);

Sulfadiazine sodium (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.

Acemetacin (TVX 1322) is a carboxymethyl ester of indometacin.

Sulfathiazole (2-Sulfanilamidothiazole), an organosulfur compound, has been served as a short-acting sulfa medicine.

2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid 2-(carboxymethoxy)-2-oxoethyl ester is a drug product that belongs to the class of Custom synthesis. It is a metabolite of loratadine, an antihistamine drug. The compound is a metabolite of loratadine, which is an antihistamine drug used for the treatment of allergies. It is produced by the oxidation of loratadine by cytochrome P450 enzymes and can be detected in urine at concentrations up to 5 ng/mL. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid 2-(carboxymethoxy)-2-oxoethyl ester has been shown to be effective in inhibiting the growth of bacteria that are resistant to penicillin and erythromycin.

Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.

Methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide (MTBC) is a drug target that is a carboxylate. MTBC has been shown to have potent inhibition activity against benzothiazine oxidases. MTBC can be used as an inhibitor of enzymes involved in the biosynthesis of benzothiazines and may be useful for the treatment of diseases such as Parkinson's disease and schizophrenia. The inhibition potential of MTBC has been unraveled through its interaction with peroxidases and other oxidases. In vitro studies have shown that MTBC can inhibit the oxidation of low molecular weight compounds by acting as a scavenger for hydrogen peroxide. This drug also exhibits unsymmetrical dehydration to produce methyl 4-(hydroxyamino)-2H-1,2-benzothiazine 1,1-dioxoate (MTBA), which is an

Applications Glimepiride-d4 (phenylethyl-a,a,b,b-d4) (cis/trans) is a useful isotopically labeled compound of Glimepiride (G410150)

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Nimesulide (R805) is a relatively COX-2 selective inhibitor with analgesic and antipyretic properties.