Botanical Source

Isoacteoside is a phenylethanoid isolated from Monochasma savatieri Franch. ex Maxim., which is an anti-inflammatory herb widely used in traditional Chinese medicine. Isoacteoside is also reported as a potential therapeutic for Alzheimers disease. The memory-improving mechanism of isoacteoside involves reducing amyloid β peptide deposition and amyloid β cytotoxicity by inhibiting amyloid β oligomerization through the catechol moiety. This promotes amyloid β degradation and reversing cortical cholinergic dysfunction, which includes the inhibition of AChE activity (Young-Ji, 2017).

Pinocembrin is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, neuroprotective, anti-inflammatory, antioxidant, and anticancer activities. Pinocembrin inhibited LPS-induced inflammatory mediators production by suppressing PI3K/Akt/NF-κB signaling pathway, it also inhibited TGF-β1-induced epithelial-mesenchymal transition (EMT) and metastasis of Y-79 cells by inactivating the αvβ3 integrin/FAK/p38α signaling pathway.

trans-Zeatin-9-glucoside-o-glucoside is a cytokinin derivative, which is a type of plant hormone involved in various growth and developmental processes. This compound is sourced from the metabolic conversion of natural cytokinins in plants. It is formed through the glycosylation of zeatin, a naturally occurring cytokinin, adding two glucose molecules. The mode of action of trans-Zeatin-9-glucoside-o-glucoside involves its role in the regulation of cell division, shoot and root growth, and the modulation of responses to environmental stimuli. As a conjugated cytokinin, it acts as a storage form that can be converted back to the active form when required, thereby regulating the availability and activity of cytokinins in plants. This compound is predominantly used in scientific studies to understand cytokinin metabolism, transport, and function in plants. Its applications extend to plant biotechnology and physiology, where it aids in elucidating the complex hormonal interactions that control plant growth and development. Understanding these interactions is crucial for advancing agricultural practices and improving crop yield and resilience.

Alisol A may be an autophagic inducer, it has anti-cancer activity, it presents inhibitory effects on cancer cell lines tested(HepG2, MDA-MB-231, and MCF-7 cells).

Quercetagetin-7-O-glucoside, a potent inhibitor of beta-glucuronidase and lysozyme release, shows anti-inflammatory activity, can significantly inhibit arachidonic acid release from membranes.

Eriodictyol

(-)-Gallocatechin gallate has cancer-preventive activities, it can precipitate cholesterol, decreasee osteoclastogenesis at 20 microM.