Botanical Source

Methyl hesperidin has potentiating effect on coronary vasodilation induced by adenosine or related compounds, It caused inhibition of nitrendipine transport in the ileum and jejunum, but not in the duodenum. Methyl hesperidin exerts no obvious toxic effects in mice of either sex when administered at a level as high as 5.0% in the diet.

Saikosaponin B2(SSb2) is an efficient inhibitor of early entry, including neutralization of virus particles, preventing viral attachment, and inhibiting viral entry/fusion, SSb2 may be of value for development as an antagonist of entry and could be explored as prophylactic treatment during the course of liver transplantation.

Taxifolin 7-O-rhamnoside is a natural product from Hypericum japonicum.

Neochlorogenic acid (NCA) is a natural polyphenolic compound found in dried fruits and other plants, has shown that phenolic acids including NCA have outstanding antioxidant, antibacterial, antiviral, and antipyretic activities, it also exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.

Dehydrocostus lactone(DCL) is exuded from sunflower roots and low DCL concentrations stimulate germination of the root parasite Orobanche cumana.

Troxerutin is a flavonoid compound, which is derived from the natural bioflavonoid rutin, typically sourced from plants such as Sophora japonica. Its mode of action is primarily through its vasoprotective, antioxidant, and anti-inflammatory properties. Troxerutin acts by stabilizing vascular endothelial cells, reducing capillary permeability, and enhancing microcirculation. It also scavenges free radicals and inhibits lipid peroxidation, which helps in mitigating oxidative stress. Troxerutin is used extensively in the medical and pharmaceutical fields for its therapeutic applications. It is primarily indicated for the treatment of chronic venous insufficiency, varicose veins, and hemorrhoids due to its capacity to improve venous tone and decrease capillary fragility. Additionally, it is also explored for its potential neuroprotective effects and its capability to ameliorate diabetic complications due to its significant antioxidant activity. Research continues into its broad-spectrum pharmacological activities and potential applications in managing cardiovascular and metabolic disorders.