Aconitum carmichaelii Debx.
Aconitum carmichaelii, also known as Chinese aconite or Fu Zi, is a species used extensively in traditional Chinese medicine for its warming and pain-relieving properties. The active compounds, including aconitine, are highly potent and are the subject of research for their potential therapeutic benefits, despite their toxicity. At CymitQuimica, we offer standardized extracts and active compounds from Aconitum carmichaelii to support research in herbal medicine, toxicology, and pharmacology.
Products of "Aconitum carmichaelii Debx."
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Hypaconitine
CAS:Hypaconitine (HA), an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism, the hepatic cytochrome P450-catalyzed metabolism of HA.Formula:C33H45NO10Purity:95%~99%Color and Shape:White powderMolecular weight:615.72Mesaconitine
CAS:Mesaconitine increases the [Ca2+]i level in endothelial cells by influx of Ca2+ from extracellular spaces, suggests that mesaconitine-induced Ca2+ influx and activation of nitric-oxide synthase in endothelial cells and, thus, induced vasorelaxation in rat aorta.Formula:C33H45NO11Purity:95%~99%Color and Shape:White powderMolecular weight:631.719Benzoylmesaconine
CAS:Benzoylmesaconine (BEN, an aconitine derivative extracted from heated-Aconiti tuber) induces the generation of CD4+ T cells antagonistic to type 2 T cells (BEN-CD4+ T cells), the combination therapy of IL-12 (an inducer of type 1 T cell responses) and BEN (an inhibitor of type 2 T cell responses) may protect TI-mice from severe HSV-1 infection.Formula:C31H43NO10Purity:95%~99%Color and Shape:PowderMolecular weight:589.682Aconine
CAS:Aconine can inhibit RANKL-induced osteoclast differentiation in RAW264.7 cells by suppressing NF-κB and NFATc1 activation and DC-STAMP expression.Formula:C25H41NO9Purity:95%~99%Color and Shape:PowderMolecular weight:499.60114-Benzoylaconine
CAS:Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell, the amino acid metabolism was the main metabolic pathway and responsible for the placental and fetal toxicity of them.Formula:C32H45NO10Purity:95%~99%Color and Shape:PowderMolecular weight:603.709
