Phytochemicals

Applications (+)-[6]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with antioxidant activity, which functions as an anti-inflammatory and antitumor agent. (+)-[6]-Gingerol down regulates proinflammatory cytokine release by macrophages. (+)-[6]-Gingerol has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Aeschbach, R. et al.: Food Chem. Toxicol., 32, 31 (1994); Tripathi, S. et al.: J. Surg. Res., 130, 318 (2006); Kim, S.O., et al.: Oncogene 24, 2558 (2005);

Applications A fatty acid ester component of volatile oil from Rhododendron anthopogonoides; shows antimicrobial activity.

Applications Spinosin is a C-glycoside flavonoid extracted from Zizhiphi Spinozae, improved pentobarbital-induced sleep. References Wang, Li. et al.: Pharm. Biochem. Behav., 90, 399 (2008);

Applications A methylated pyrollidine which is an essential part of the structure of Cefipime (C242750) often analyzed via ion chromatography. A cigarette smoke constitutent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Prasanna, S.J. et al.: J. Chrom. Sci., 48, 830 (2010); Adam, T. et al.: Anal. Chim. Acta, 657, 36 (2010);

Stability Light Sensitive Applications A naturally occurring insecticide and acaricide with possible neurotoxic effects on neuroblastoma cells. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lee, B.K. et al.: Toxicol. Lett., 157, 49 (2005); Srivastava, S. et al.: Pharmac. Biol., 39, 226 (2001);

Applications Withanolide A, is a neuritogenic steroid. It may act as deterrent for feeding insect larva and other herbivores. Withaferin A, causes activation of Notch2 and Notch4 in human breast cancer cells, and thus used as novel anticancer agents. References Liffert, R., et al.: Chemical Science, 4, 2851 (2013); Lee. J., et al.: Breast Cancer, Res. treat., 136, 45 (2012);

Stability Hygroscopic Applications 8-Oxo-2’-deoxyadenosine is the first example of a native DNA lesion that stabilizes human telomeric G-quadruplex DNA. References Aggrawal, M., et al.: Biochem. Biophy. Res. Comm., 421, 671 (2012); Singh, T.A., et al.: J. Phy. Chem., 114, 16611 (2010);

Applications Platycodin D is a known inhibitor of the proliferation of human gastric cancer cells as well as inducing apoptosis. It also causes anti-atherosclerotic. References Wu, J. et al.: Biol. Pharm. Bull. 35, 1216 (2012); Chun, J. et al.: J. Cell. Biochem., 114, 456 (2013);

Applications (1R,​2R,​5R)​-​2-​Isopropyl-​5-​methylcyclohexanol is used in the tetrahydropyranylation of alcohols. References Magyar, A. et al.: Catal. Lett., 145, 1876 (2015);

Stability Hygroscopic Applications (+)-ar-Turmerone is an anti-tumor and immune activating agent, which maintains a cytotoxic effect in cancer cells. Antimicrobial agent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Kim, D. et al.: Int. J. Mol. Med., 31, 386 (2013); Dehghanzadeh, N. et al.: Asian. J. Exp. Biol. Sci., 3, 767 (2012);