Phytochemicals

Applications Saikosaponin C is an inhibitor of liposaccharide-induced apoptosis through suppression of caspase-3 activation. Neuroprotective agent. References Li, Z. et al.: J. Ethnopharmacol., 148, 794 (2013); Lee, T. et al.: Biochem. Biophys. Res. Comm., 445, 615 (2014);

Applications A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner. References Huang, Y. et al.: Drug Dev. Res., 69, 196 (2008); Huang, Y. et al.: J. Pharmacol. Sci., 108, 198 (2008); Song, J. et al.: J. Pharmacol. Sci., 113, 409 (2010);

Applications Various benzothiazole-benzamides synthesized were evaluated for their analgesic and antidepressant activities. References Porsolt, R., et al.: Nature, 266, 730 (1977), Foster, J., et al.: Bioorg. Med. Chem., 7, 2415 (1999), Caliendo, G., et al.: Eur. J. Med. Chem., 36, 517 (2001), Rana, A., et al.: Eur. J. Med. Chem., 43, 1114 (2008),

Applications 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide, has been shown to be one of the potential novel biomarkers of peroxisome proliferation in the rat. References Ringeissen, S., Biomarkers, 8, 240 (2003); Shibata, K., et al.: Biosci. Biotech. and Biochem., 77, 2105 (2013);

Stability Light Sensitive Applications Morusin is an inhibitor of human cervical cancer stem cell growth, attenuating NF-kB activity, and initiating apoptosis. References Wang, L. et al.: Mol. Cell. Biochem., 379, 7 (2013);

Applications A nicotine derivative. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Joyce, N.J., et al.: Heterocycles, 29, 7, 1335 (1989),

Stability Light Sensitive Applications Praeruptorin B is a bioactive constituent of Peucedani Radix, a traditional Chinese medicinal herb used in the treatment of respiratory and pulmonary disorders. References Song, Y. et al.: Rapid. Commun. Mass. Spect., 25, 719 (2011);

Applications An intermediate in the preparation of Alfentanil and Sufentanil Citrate References Colapret, J., et al.: J. Med. Chem., 32, 968 (1989),