Phthalate Standards

Applications Decyl Hexyl Phthalate is an phthalate esters used as plasticizers and additives. Used in toxiciology studies as well as risk assessment studies of food contamination that occurs via migration of phthalates into foodstuffs from food-contact materials (FCM). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Awad, N.E., et al.: Bull. Factul. Pharma., 40, 233 (2002); Harris, C.A., et al.: Environ. Health. Perspect., 105, 802 (1997);

Applications Phosphoric Acid Tris(2-​methylphenyl) Ester is a metabolic precursor to neuropathy target esterase (NTE) inhibitors. It is also a flame retardant and plasticizer in marine fish and human milk. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Li, W., et al.: Toxicol. Lett., 98, 139 (1998); Sundkvist, A., et al.: J. Environ. Monitoring, 12, 943 (2010)

Applications Isophthalic-2,4,5,6-d4 Acid (CAS# 148472-48-4) is a useful isotopically labeled research compound.

Stability Hygroscopic Applications An oxidative metabolite of Bis(2-ethylhexyl)phthalate (DEHP) (B433850), as biomarker for human exposure assessment. References Gray, T., et al.: Toxicol. Lett., 11, 141 (1982), Albro, P., et al.: Drug Metab. Rev., 21, 13 (1989), Gray, L., et al.: Toxicol. Sci., 58, 350 (2000),

Applications Labelled Dicyclohexyl Phthalate (DCHP) metabolite. References Okubo, T., et al.: Biol. Pharm. Bull., 26, 1219 (2003), Silva, M., et al.: J. Anal. Toxicol., 29, 819 (2005), Matsumoto, M., et al.: Reg. Toxicol. Pharmacol., 50, 37 (2008),

Applications 2-(((4-Methyl-7-oxyooctyl)oxy)carbonyl)cyclohexanecarboxylic Acid is a secondary oxidized metabolite of the di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) monoester (MINCH) and may be used as biomarkers of DINCH exposure. DINCH is a major substitute for some high molecular weight phthalates that adversely affect reproductive function. References Schutze, A., et. al.: J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 895, 123 (2012)

Stability Hygroscopic Applications A glucuronide conjugate of the phthalate ester metabolite Monomethyl Phthalate (M566540). References Thompson, R.M. et al.: Drug Metab. Disp., 1, 489 (1973);