Environmental Regulatory Standards

Applications Labelled analogue of Dicyclohexyl Phthalate, a phthalate ester used as a plasticizer as well as being present in cosmetic products. Dicyclohexyl Phthalate that is a weak drug-type inducer of hepatic xenobiotic metabolism. References Lake, B.G. et al.: Acta Pharmacol. Toxicol., 51, 217 (1982); Tsutsumi, N. et al.: Optic. Mat., 29, 435 (2006);

Applications Fenpropidin-d10 is the labeled analogue of Fenpropidin (F249470), a fungicide. References Leroux, P. Walker, A.: Eur. J. Plant Path., 135, 683 (2013); Zhao, H., et. al.: Ecotox. Environ. Safe., 77, 52 (2012)

Applications Metribuzin DK is a selective triazine herbicide used in the control of broadleaf weeds. Used in the protection of vegetable and fruit crops. Pesticide. References Xie, Y. et al.: Microchem. J., 133, 468 (2017);

Applications 2,5-Dichloro-1,3-benzenedicarbonitrile is a metabolite of the fungicide 2,4,5,6-tetrachloroisophthalonitrile (TPN) in soil. References Sato, K., et al.: Biol. Fert. Soils, 3, 205 (1987)

Stability Moisture Sensitive Applications Sebuthylazine-d5 (ethyl-d5) (CAS# 1219805-56-7) is a useful isotopically labeled research compound.

Applications Diacetoxyscirpenolis is a trichothecene mycotoxin produced by various Fusarium strains. Diacetoxyscirpenol was found to occur in cereals conjugated to glucose and other sugars. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Rasmussen, P.H., et al.: Mycotoxin, Res., 28, 181 (2012); Scauflaire, J., et al.: Euro. J. Pathol., 133, 911 (2012); Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);

Applications Melamine Cyanurate is a crystalline complex formed between Melamine (M208700) and Cyanuric Acid (C987715), and is unique in that it is a halogen-free flame retardant. References Isbasar, C. et al.: J. Ana. App. Pyro., 98, 221 (2012); Horrocks, A.R. et al.: Polym. Degrad. Stab., 97, 645 (2012);

Applications rac-cis-Permethrinic acid is a potent insecticide used in the agricultural industry to eliminate unwanted pests from crops. rac-cis-Permethrinic acid is also metabolite of pyrethroid compounds, a group of pesticides that are relatively low toxicity (to organisms that are not intended to be targeted) and biodegradable. References Kale, M., et al.: Toxicol. Lett., 105, 197 (1999); Leszczynski, J., et al.: J. Am. Chem. Soc., 115, 5891 (1993); Sodurlund, D. & Bloomquist, J.: Ann. Rev. Entomol., 34, 77 (1989)

Applications 2,3,4,5,6-Pentabromophenol is used in the synthesis of alkyltrichlorosilane surface modifiers for biomedical applications. Also used in the synthesis of flame retardant polymers. References Blaszykowski, C. et al.: Langmuir, 28, 2318 (2012); Alam, S. et al.: Ann. Tech. Conf. Soc. Plas. Engineers., 3, 2400 (2011);

Applications 2,4,5-Trichlorophenoxyacetic Acid Isobutyl Ester is a component in herbicide formulation used in the protection of crops. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Noble, A. et al.: Pest. Sci., 28, 203 (1990);

Applications Melengestrol Acetate is an orally active progestational steroid. Progestogen; growth promotant. References Patton, M., et al.: Zoo Biol., 26, 311(2007), Sellin, M., et al.: Environ. Toxicol. Chem., 28, 2443 (2009), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Sanseverino, J., et al.: Toxicol. Sci., 107, 122 (2009),

Applications Butralin is a pesticide used in the protection of crops from weeds and other pests. It is a mitosis inhibitor that disrupts the cell cycle in germinating plants. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Elmore, C. et al.: Weed Res., 32, 7 (1992);

Applications Isoprocarb is a non-systematic carbamate insecticide. Isoprocarb functions by reversibly inactivating the enzyme acetylcholinesterase in insects. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Voss, G.: Anzeig. Schaedling., 40, 73 (1967); Metcalf, R.L. et al.: J. Agric. Food Chem., 15, 1022 (1967); Nishioka, T. et al.: Pest. Biochem. Physiol., 6, 320 (1976);

Stability Very Hygroscopic Applications Metolachlor ESA-d6 Sodium Salt is deuterium labelled salt form of Metolachlor ESA (M338860) which is a synthetic herbicide. References Mai, H., et al.: Aquat. Toxicol. 147, 48 (2014); McCarty, G. W., et al.: Sci Total Environ 473-474, 473 (2014);

Applications Pentabromobenzene is a flame retardant and a standard for environmental testing and research. References Dodson, R. E., et al.: Environ. Sci. Technol. 51, 4860 (2017); EPA. Method 1668, (EPA 821-R-00-002) (1999)

Impurity Lamivudine EP Impurity J Applications (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione (Lamivudine EP Impurity J) is an impurity of Lamivudine (L172500). (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is also being further studied to determine its potential as an anti-HIV agent. References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993)