APIs for research and impurities

Stability Air Sensitive, Hygroscopic Applications The active metabolite of Erdosteine (E596050). References Dechant, K., et al.: Drugs, 52, 875 (1996), Braga, P., et al.: Arzneim.-Forsch., 49, 344 (1999), Braga, P., et al.: Antimicrob. Agents Chemother., 43, 1013 (1999),

Sodium 5-(diphenylphosphinyl)pentanoate is an impurity present in the drug product and is an analytical reference material for metabolism studies. It is a natural compound that has been custom synthesized for use as a synthetic standard. This substance is used in drug development and research, including the study of pharmacokinetics, metabolism, and toxicology. Sodium 5-(diphenylphosphinyl)pentanoate also serves as an impurity standard for HPLC analysis. The purity of this substance is high enough to meet the standards set by the pharmacopoeia.

Applications Labelled Fluconazole (F421000). Used as an antifungal. References Richardson, K., et al.: Antimicrob. Ag. Chemother., 27, 832 (1985),

Please enquire for more information about NP-AHD-13C3 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Des[2-(1,2,4-triazolyl)] itraconazole-2-isocyanate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Stability Hygroscopic Applications Cabergoline is an ergot derivative and a dopamine D2-receptor agonist (1,2,3). It inhibits the secretion of prolactin and growth hormone. References (1) Kvernmo, T., et al.: Clin.Ther. 28 1065 (2006)(2) Boutinaud, M., et al.: J Dairy Sci. 99, 5707 (2016)(3) Hutton, J.T., et al.: Neurology, 46, 1062 (1996

Please enquire for more information about Dihydro artemisinin tetrahydrofuran acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (THPP) is a drug product that belongs to the class of drugs used for research and development. It has been shown to have antiinflammatory properties in animal models. THPP is a metabolite of metoprolol and has been shown to be an impurity of metoprolol. The analytical properties of THPP are not yet known. Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3--yl)-1--piperidinyl]ethyl]-2--methyl--4H--pyrido[1,2--a]pyrimidin--4one

Please enquire for more information about Aprepitant β-glucuronide sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ethylene terephthalate (ET) is a polymer that is used in the textile industry. ET is made by the reaction of ethylene glycol with terephthalic acid, which results in the formation of linear polyesters. This process can be done as a batch or continuous process. The polymerization process starts by heating the reactants and then adding an appropriate catalyst to initiate the reaction. This step is called “extrusion” and it involves forcing the reactants through a small hole under high pressure, which creates long strings of molecules of polyester. After this, the polymer strands are heated to remove any remaining water and are stretched out into long fibers under tension. These fibers are then drawn to make them thinner and stronger before they are cut into lengths. Finally, they are wound onto spools for later use.

Stability Hygroscopic Applications N-Formylcytisine is a derivative of Cytisine (C998500) that can be used as a ligand for neuronal nicotine receptors. References Boido, C.C., et al.: Farmaco, 58, 265 (2003)

Applications Lablled Caffeine (C080100). Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);