APIs for research and impurities

Applications A deuterated selective acetylcholinesterase inhibitor. Useful for the treatment of Alzheimer's disease. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bickel, U., et al.: Clin. Pharmacol. Ther., 50, 420 (1991), Maelicke, A., et al.: Drugs Dis Today, 1, 53 (1996), Sauvaltre, T., et al.: J. Med. Chem., 50, 5311 (2007),

Moclobemide N-oxide is a metabolite of moclobemide, an antidepressant drug. It is a white to off-white crystalline powder with a molecular formula of C14H14N2O4 and a molecular weight of 237.3. Moclobemide N-oxide is used in the treatment of depression, but it has not been approved for clinical use in the United States. Moclobemide N-oxide is extensively metabolized by cytochrome P450 enzymes, which may lead to variations in its activity among patients. The following are examples of high quality descriptions: Rifapentine is an anti-tuberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency

Cyamemazine is an antipsychotic drug that has been used for the treatment of schizophrenia and other psychotic disorders. N-Desmethyl cyamemazine maleate, a metabolite of cyamemazine, has been shown to have neuroprotective effects in vitro.

Varenicline Diamine Impurity - Bio-X ™ is a diamine impurity of varenicline, a medication used for smoking cessation. Varenicline acts as a partial agonist at α4β2 nicotinic acetylcholine receptors, which are involved in the addictive effects of nicotine. Researchers utilize this compound to study its effects on nicotine addiction and develop potential treatments for smoking cessation. This impurity is used as a reference standard or analytical tool in the quality control and manufacturing process of varenicline and serves as an important marker for ensuring the purity and consistency of varenicline during its production, helping to maintain the medication's safety and efficacy for patients seeking to quit smoking.This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Stability Moisture Sensitive Applications Oxyfedrine acts as a vasodilator affecting the coronary base flow. References Baraka, Y. et al.: J. Drug Res., 12, 161 (1980);

Applications Nonsteroidal anti-inflamatory agent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bird, H.A., et al.: Curr. Med. Res. Opin., 8, 9 (1982), Gonzalez, J.P., et al.: Drugs, 34, 289 (1987), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs. Excip., 22, 431 (1993),

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