APIs for research and impurities

4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is a drug that has been developed for the treatment of cancer. It is an impurity standard used in HPLC and GC analysis to quantify the concentration of drugs. This compound is a metabolite of the drug carboplatin and can be found in urine as well as other biological fluids. Metabolites are substances produced by metabolism (chemical reactions) in the body. 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one can also be found naturally in plants such as ivy or wild parsnip.

N-Acetyl zonisamide is a drug that is used in the treatment of epilepsy. It has a broad spectrum of activity and has been shown to be effective against seizures caused by both genetic and acquired conditions. N-Acetyl zonisamide's mechanism of action is not fully understood, but it may involve inhibition of carbonic anhydrase, modulation of serotonergic systems, and antagonism at adenosine receptors. Zonisamide also binds to glutamate and dopamine receptors in the brain, which may contribute to its clinical effects.

7β,25-Dihydroxycholesterol is a steroid precursor that is synthesized in the liver and is converted to other steroid hormones. It has been shown to be important in immune function and as a regulator of cholesterol metabolism. In addition, 7β,25-Dihydroxycholesterol can bind to follicle cells and immune cells, activating signalling pathways. This compound has been shown to have an immunosuppressive effect on the humoral immune response by blocking antibody production. The receptor for 7β,25-Dihydroxycholesterol has been identified as GPER1. Knockout mice studies have shown that this receptor plays a role in regulating the number of plasma cells and oxysterols.

Compounds with other nitrogen function, nesoi

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Impurity Clindamycin Phosphate EP Impurity E Stability Hygroscopic Applications Clindamycin Hydrochloride (Clindamycin Phosphate EP Impurity E) is a semi-synthetic antibiotic prepared from Lincomycin. Antibacterial. References Birkenmeyer, R.D., et al.: J. Med. Chem., 13, 616 (1970); Oesterling, et al.: J. Pharm. Sci., 59, 63 (1970); Gray, J.E., et al.: Toxicol. Appl. Pharmacol., 21, 516 (1972); Brown, L.W., et al.: Anal. Profiles Drug Subs., 10, 75 (1981);

Please enquire for more information about Methyl 1-(4-bromophenyl)-1H-pyrazole-4-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Olmesartan methyl ketone is a synthetic drug product that is used as an analytical reference standard. It has been shown to be metabolized in vivo to its active form, olmesartan. The chemical structure of this compound is similar to the active metabolite of other angiotensin II receptor blockers, such as losartan and valsartan. This compound is an impurity in the API Olmesartan medoxomil, which is a potent angiotensin II receptor blocker used for the treatment of hypertension (high blood pressure).

Please enquire for more information about Depyrazine 6,8-dinitrophenyl varenicline including the price, delivery time and more detailed product information at the technical inquiry form on this page

(S)-3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is a polymerase chain reaction (PCR) reagent that is used as a building block for the synthesis of five membered ring lactams and dihedral polymers. This compound is synthesized by chemoenzymatic coupling of propanamine with trifluoroacetic acid in the presence of methyl groups, followed by catalytic hydrogenation to yield the desired product. The asymmetric synthesis of this compound was achieved through chiral resolution using NMR spectroscopy.