APIs for research and impurities

Applications Antipsychotic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Enniatin B4 is a potent inhibitor of cancer cells that has been shown to disrupt the cell cycle and induce apoptosis in breast cancer cell lines. This compound is derived from Chinese medicine and is a protein that specifically targets tumor cells, making it an effective anticancer agent. Enniatin B4 has also been found to be an inhibitor of leukemia cells and has shown activity against aryl hydrocarbon receptor (AhR)-dependent cancers. In human studies, this compound has demonstrated promising results as a potential treatment for various types of cancer due to its ability to selectively target cancer cells while leaving healthy cells unharmed.

Cyromazine (CGA-72662) is an ectoparasiticide.

Cetirizine metabolite

Applications Trimethylarsinoxide is an organic derivative of arsine and is a building block to other organoarsenic compounds. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Marquez-Garcia, B., et al.: J. Geochem. Explorat., 119, 51 (2012); Button, M., et al.: Environ. Pollut., 169, 74 (2012);

Applications Ethylestrenol is an anabolic steroid. Ethylestrenol is an illegal growth promoter used in livestock and are often tested for as part of a routine screening program for forbidden growth promoters. References Van Puymbroeck, M. et al.: J. Chrom. B Biomed. Sci. Appl., 728, 217 (1999); Wekhe, S.N. et al.: J. Appl. Animal Res., 5, 119 (1994);

9-Chloro nevirapine (9CNP) is a synthetic drug that is used as an anti-retroviral agent. 9CNP binds to the HIV reverse transcriptase enzyme and blocks the synthesis of viral DNA and RNA, which prevents HIV from multiplying. 9CNP also has a high affinity for the human liver cytochrome P450 enzyme CYP3A4. This means that it may be metabolized by this enzyme, leading to increased levels of active metabolites in the blood.

Tenofovir disoproxil related compound B is a peptidyl prodrug that is metabolized by esterases to tenofovir. It has been shown to be an effective agent against Mycobacterium tuberculosis and other bacterial species. Tenofovir disoproxil related compound B was also found to inhibit protein synthesis in Mycobacterium avium and Mycobacterium smegmatis, but not in Escherichia coli. This drug binds to the ribosome's 30S subunit, which blocks the binding of aminoacyl-tRNA and prevents the formation of peptide bonds. The mechanism of action for this drug is similar to that of the antibiotic erythromycin.

Applications Dienogest-d8 (major) is labelled derivative of 19-Nortestosterone. It is used in combination with estrogen as oral contraceptive. References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998)

Applications Sulbactam Pivoxil is a prodrug of the semi-synthetic β-lactamase inhibitor Sulbactam (S699195). References Foulds, G. et al.: Curr. Chemother. Infect. Dis., Proc. Int. Congr. Chemother., 11, 353 (1980); Pei, Q. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 879, 2000 (2011);