APIs for research and impurities

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This drug product is a custom synthesis, CAS No. 2200280-97-1, drug development, Metabolite, Synthetic, Impurity standard, Metabolism studies, API impurity, Natural (pharmacopoeia), analytical (HPLC standard), Research and Development (High purity). It is a metabolite of the drug N-[4-amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)sulphinyl]-2-hydroxy-2-methylpropanamide. This compound has been shown to have high affinity for the dopamine receptor with an IC50 of 0.5 nM.

Applications A ring-opened analog of Fentanyl (F274990). An opioid analgesic with potency similar to morphine. References Casy, A.F. et al.: J. Pharm. Pharmacol., 19, 17 (1967); Dosen-Micovic, L. et al.: Elec. Conf. Heterocyc. Chem., 157 (1998);

Applications A steroid used as a probe in the detection of different viruses. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lin, L. et al., J. Virol. Methods, 171, 91 (2010); Finnegan, C.J. et al., J. Virol. Methods, 121, 223 (2004); Rubio, L. et al., J. Virol. Methods, 114, 105 (2003)

Stability Hygroscopic Applications A metabolite of Lansoprazole, as gastric pump inhibitor. References Uno, T., et al.: J. Clin. Pharmacol., 45, 690 (2005), Saito, M., et al.: Brit. J. Clin. Pharmacol., 59, 302 (2005),

Zm 306416 hydrochloride is a new synthetic compound with antimicrobial activities. It has been shown to be active against gram-positive bacteria, gram-negative bacteria, and fungi. Zm 306416 hydrochloride can also protect mice from carbon tetrachloride-induced liver damage by reducing serum bilirubin levels and inhibiting lipid peroxidation. This compound can also be used as a photocatalyst in organic synthesis.

Stability Hygroscopic Applications Labelled Vigabatrin. A novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic. References Vajda, F., et al.: Clin. Neurosci., 7, 88 (2000), Beghi, E., et al.: Lancet. Neurol., 3, 618 (2004), Sagirli, O., et al.: J. Pharmaceut. Biomed., 42, 618 (2006),