Amino Acids (AA)

3-Chloro-4-methoxy-benzylamine is a quinoline derivative that is used in the synthesis of pharmaceuticals. It is a chlorinating agent that forms a hydrogen bond with other molecules to produce an alkylated product. 3-Chloro-4-methoxy-benzylamine has been shown to inhibit the activity of cyclic guanosine monophosphate (cGMP) and phosphodiesterase type 5 (PDE5). This inhibition leads to an anti-obesity effect in mice by promoting weight loss. 3CMB also inhibits the production of amyloid beta peptide and prevents Alzheimer's disease, as well as inhibits seizures caused by epilepsy.

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(2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoic acid is an analog of the amino acid serine. The synthesis of this compound is a two step process that starts with the asymmetric synthesis of the L-(+)-serine methyl ester. This ester is then hydrolyzed to form (2S,3S)-(2S,3R)-2-amino-3-hydroxy-4-methylpentanoic acid. (2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoic acid has been shown to inhibit tumor growth and induce apoptosis in cancer cells. It also inhibits serine proteases by binding to their active site and inhibiting their function. In addition, it has been shown to inhibit protein synthesis in human pancreatic cells.

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Beta-Chloro-L-alanine methyl ester HCl is a crystallizing and reutilized chemical that has been synthesized from d-serine. This synthetic compound can be found in the environment, where it is formed by thionyl chloride and chlorination of an alkyl chloride. Beta-Chloro-L-alanine methyl ester HCl is used as a decoloring agent for filtration, which removes color from substances such as coffee beans. It also serves as a chlorinating agent for the removal of organic impurities, such as methyl esters or hydrocarbons. The product is available in two forms, including the crystallizing form and the reutilized form. The crystallizing form is made by refluxing beta-chloro-L-alanine methyl ester HCl with sodium bicarbonate and ethanolamine. The reutilized form is made by adding hydrochloric acid to beta-chloro

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1-O-Octadecyl-2-O-benzyl-sn-glycerol (ODBG) is a novel antiviral drug that is being developed for the treatment of HIV. ODBG inhibits HIV by binding to the virus and preventing it from entering cells, which prevents the virus from replicating. ODBG has been shown to be effective against other viruses as well, such as herpes simplex virus and respiratory syncytial virus. ODBG is a lipid molecule that can cross cell membranes and has been shown to have low toxicity in animal studies. This drug also has potential to be used as an oral medication for patients with HIV.

Applications N-(2-Methylphenyl)-2-butenamide, is used as an intermediate in the synthesis of Crotamiton, which is a drug that can be used as scabicidal, and antipuritic (anti-itching drug). References Hirota, M. et al.: Therp. Res., 34, 235 (2013);

Applications N-Carbobenzoxy-S-phenyl-L-cysteine methyl ester is used in the preparation of γ-amino β-ketoesters by cross-Claisen condensation of α-amino acid derivatives with alkyl acetates. References Honda, Y., et al.: Tetrahedron, Lett., 44, 3163 (2003);

2-Methoxyphenylboronic acid is a boron compound that can react with organic compounds to form new carbon-carbon bonds. It is used in biological systems as an enzyme inhibitor and has been shown to be specific for epidermal growth factor receptor. 2-Methoxyphenylboronic acid binds to the active site of epidermal growth factor (EGF) receptor, which prevents the activation of the EGF signaling pathway. This inhibition results in decreased proliferation of epidermal cells and leads to the inhibition of cell growth. 2-Methoxyphenylboronic acid also inhibits the production of proton by binding to ATPase, which may result in a decrease in ATP synthesis and cell death.

Sodium 2-fluoro-alpha-methyl[1,1'-biphenyl]-4-acetate is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the activity of enzymes involved in inflammatory reactions. It has shown to be an effective treatment for the reduction of pain and inflammation associated with certain diseases, including rheumatoid arthritis. The drug also binds to DNA and blocks its ability to form supercoiled strands. This binding prevents transcription of genetic information from DNA into RNA, which is needed for protein production. Sodium 2-fluoro-alpha-methyl[1,1'-biphenyl]-4-acetate has been shown to inhibit bcl2 protein expression and may increase the risk of developing cancer. The drug can cause adverse effects such as headache and stomach upset when taken at high doses.

4-Methyloxy-phenyl)-piperazin-1-yl]-phenylamine is an organic compound that has a reactive silicon group. It contains two phenyl groups, one of which is attached to the silicon. This compound exhibits phase equilibrium in water and can be used as a monomer for fabricating inorganic materials with orderly patterns, such as glass and metal oxides. This product also has impurities and can be grown at different rates depending on the conditions, such as temperature. The optical properties of 4-methyloxy-phenyl)-piperazin-1-yl]-phenylamine are dependent on its environment and it has been shown to have exothermic properties when reacting with iron powder.

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8-Methoxy-1-octanol is a glycoside that is the product of maltose, which is an alcohol, and glycosylation. It is synthesized by reacting maltose with glycosylation reagents such as thiols or alcohols. 8-Methoxy-1-octanol has been found to be the most stable of the long chain glycosides studied so far. The synthetic process for 8-methoxy-1-octanol starts with a reaction between stannic chloride and glycerol in ethanol to produce octaacetate. This product reacts with methanol to produce methoxymaltoside, which then reacts with hydrochloric acid to produce 8-methoxy-1-octanol.

4-Phenoxyphenylacetic acid is a ligand that is used as a catalyst. It has been shown to catalyze the hydrochlorination of 4-ethoxybenzene to 4-chlorobenzene. 4-Phenoxyphenylacetic acid binds to metals and forms complexes with them, which increases its catalytic activity. The stability of the complex is also increased by the presence of heteroatoms such as chlorine or bromine on the ring system. Ligands that interact with metals are more electronegative than those that do not, and this can affect their stability in the complex.

1-[(4-Methylphenyl)sulfonyl]piperidine-4-carboxylic acid is a synthetic intermediate that can be used in the synthesis of pharmaceuticals. It is also a promising candidate for use as a catalyst in organic synthesis. The use of 1-[(4-methylphenyl)sulfonyl]piperidine-4-carboxylic acid has been shown to provide high yields, traceless reactions, and excellent functional group tolerance. Organocatalytic methods are used to produce this compound by reaction with chloroacetic acid and phenylmagnesium bromide. The mechanism of this reaction is thought to involve an organocatalytic addition of chloride ion to the carbonyl group followed by deprotonation at the alpha position on the piperidine ring. 1-[(4-Methylphenyl)sulfonyl]piperidine-4-carboxylic

Substance P is a neuropeptide that is found in the central nervous system. It is also found in the gastrointestinal tract and plays a role in the regulation of smooth muscle contraction. Substance P has been shown to be involved in inflammatory responses, immune responses, and regulation of water and electrolyte balance. The maximal response of substance P occurs at concentrations between 0.1 to 1 nM and its inhibitory effect on the apical Ca2+ response occurs at concentrations between 10-100 nM. In addition, substance P has been shown to have an excitatory effect on 5-HT7 receptors with subunit composition GluN1/GluN2A/GluN2B/GluN3A/5-HT7(H).

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Applications Thieno[2,3-d]pyrimidine derivative.

Applications Methyl(4-methylnaphthalen-1-ylmethyl)amine-d3 is the isotope analog of Methyl(4-methylnaphthalen-1-ylmethyl)amine. Methyl(4-methylnaphthalen-1-ylmethyl)amine is a reagent in the preparation of heterocyclic compounds as enoyl-acyl carrier protein reductase FabI inhibitors and antibacterial agents. References Stuetz, A., et al.: J. Med. Chem., 29, 112 (1986); Berman, J., et al.: PCT Int. Appl., 2004:515512 (2004)

5-Iodo-2-methoxybenzoic acid methyl ester is a compound with the molecular formula of C8H7INO3. It is a white crystalline solid. The compound is used as an intermediate for organic synthesis and for research purposes. 5-Iodo-2-methoxybenzoic acid methyl ester has been shown to be an inhibitor of transcription, translation, and RNA processing in cell culture experiments. This drug also blocks the replication of DNA by binding to the enzyme DNA polymerase, thereby preventing DNA replication.

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4-Methoxy-2-iodoaniline is a synthetic compound that is used as an anti-cancer drug. It has been shown to have potent anti-cancer effects in animal models, with the most pronounced activity being against solid tumors. In addition, 4-methoxy-2-iodoaniline has been shown to inhibit the growth of cancer cells by binding to proteins and inhibiting their function. This compound inhibits the production of tropane alkaloids and coerulescine, which are important for the synthesis of DNA and RNA. The anti-cancer properties of this compound are mainly due to its ability to bind to DNA and prevent transcription.

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Antioxidant; mucolytic agent; anti-viral against influenza A viruses

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2-Methylnaphthol[1,2-d]thiazole is a dyestuff that is used in the production of dyes. It has a sulfurous odor and reacts with acids. 2-Methylnaphthol[1,2-d]thiazole is used for the desulfurization of organic compounds. 2-Methylnaphthol[1,2-d]thiazole has been shown to be a strong fluorescer under UV light and can be quantified using the fluorescence method. The byproduct of this reaction is nitrous oxide (N2O). This dyestuff also exhibits high thermostability and constant emissions when heated.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol sulfate dihydrate (benserazide) is a cholinergic agent that has been shown to increase the release of acetylcholine by acting as an agonist at nicotinic receptors. It increases the amount of acetylcholine released in the brain and can be used for the treatment of Alzheimer's disease. Benserazide has also been shown to have a depressant effect on the respiratory system, which can be beneficial for lung diseases. This drug also has anti-inflammatory properties and can inhibit growth factor synthesis.

Glycine dimethylamide is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

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Applications 4-(4-Methoxyphenyl)-1-butanol is used as a reactant in nonimidazole histamine H3 receptor ligands preparation with combined inhibitory histamine N-methyltransferase activity. References Apelt, J., et al.: J. Med. Chem., 45, 1128 (2002);

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2-Methoxyphenylhydrazine hydrochloride is a chemical that is used as a research scaffold, building block, or intermediate. It can be used in the synthesis of complex compounds with high quality and purity. This product is soluble in water and alcohols. 2-Methoxyphenylhydrazine hydrochloride has CAS No. 6971-45-5 and a molecular weight of 183.2 g/mol.

4-Methoxy-6-methyl-2H-pyran-2-one is a synthetic chemical that belongs to the class of diazonium salts. It has been shown to have inhibitory activities against energy metabolism in vitro studies. The reaction rate of this compound is increased by hydrogen bond and decreased by modifiers, which are organic compounds that can bind to the active methylene group. 4-Methoxy-6-methyl-2H-pyran-2-one has been synthesized using an asymmetric synthesis process. This process involves the use of two different reactants to produce a single product with two different chiral centers.

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(S)-3-Methoxypyrrolidine is a chiral compound that has been shown to have anticancer activity. It is a photoinduced drug that can be activated by light of specific wavelengths. The high expression of (S)-3-methoxypyrrolidine in tumor cells makes it a potential target for cancer therapy. This compound inhibits the growth of tumor cells by binding to FGFR4 and inhibiting the downstream signaling pathway. (S)-3-methoxypyrrolidine is also an indolizidine alkaloid with pharmacological, pharmacokinetic, and pharmacodynamic properties that are similar to those of the more well-known drug paclitaxel.

3-Methoxybenzenethiol is a reactive chemical that can be used for the synthesis of amines. It has an optimal reaction at a particle size of 10 nm and a reaction rate of 0.5 s-1. 3-Methoxybenzenethiol is an organic substance that contains hydroxyl, carbonyl, and amino groups. The hydroxyl group is present in the form of ether linkages with other molecules to form a particle. This substance has been shown to have surface-enhanced Raman spectroscopic properties and can be used to examine the molecular electrostatic potentials of surfaces. 3-Methoxybenzenethiol has a molecular weight of 142 g/mol, which makes it soluble in organic solvents such as diethyl succinate. The three isomers are shown below: 3-methoxybenzenethiol (I) 3-hydroxybenzene thiol (II

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