CAS 1115-70-4: Metforminhydrochlorid
Beschreibung:
Metforminhydrochlorid ist ein orales antihyperglykämisches Mittel, das hauptsächlich zur Behandlung von Typ-2-Diabetes mellitus eingesetzt wird. Es gehört zur Klasse der Biguanide und wirkt, indem es die hepatische Glukoseproduktion verringert, die Insulinempfindlichkeit erhöht und die periphere Glukoseaufnahme und -nutzung verbessert. Die Substanz erscheint als weißes bis off-white kristallines Pulver, das in Wasser löslich ist, aber eine begrenzte Löslichkeit in organischen Lösungsmitteln aufweist. Seine chemische Formel ist C4H11N5·HCl und es hat ein Molekulargewicht von etwa 165,63 g/mol. Metforminhydrochlorid wird typischerweise in Tablettenform verabreicht und ist bekannt für sein günstiges Sicherheitsprofil, wobei gastrointestinale Nebenwirkungen die häufigsten sind. Es ist auch mit einem geringen Risiko für Hypoglykämie verbunden, wenn es allein verwendet wird. Darüber hinaus haben Forschungen potenzielle Vorteile über die glykämische Kontrolle hinaus gezeigt, einschließlich kardiovaskulärer Schutz und Gewichtsmanagement. Wie bei jedem Medikament ist es wichtig, Metformin unter ärztlicher Aufsicht zu verwenden, wobei Kontraindikationen und potenzielle Wechselwirkungen mit anderen Medikamenten zu berücksichtigen sind.
Formel:C4H11N5·ClH
InChl:InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChI Key:InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES:C(NC(=N)N)(N(C)C)=N.Cl
Synonyme:- 1,1-Dimethylbiguanide Hydrochloride
- 3-(Diaminomethylidene)-1,1-Dimethylguanidine Hydrochloride (1:1)
- Apo-Metformin
- Apophage
- Benofomin
- Biguanide, 1,1-dimethyl-, hydrochloride
- Biguanide, 1,1-dimethyl-, monohydrochloride
- Dabex
- Denkaform
- Dextin
- Diabefagos
- Weitere Synonyme anzeigen
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METFORMIN HYDROCHLORIDE CRS
CAS:METFORMIN HYDROCHLORIDE CRSFormel:C4H12ClN5Farbe und Form:PowderMolekulargewicht:165.6246Metformin hydrochloride
CAS:Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.Formel:C4H12ClN5Reinheit:97.53% - 99.00%Farbe und Form:White Or Almost White Crystals Solid CrystallineMolekulargewicht:165.63Metformin hydrochloride, EP grade
CAS:Formel:C4H11N5·HClReinheit:98.5 - 101.0 % (dried substance)Farbe und Form:White or almost white crystalsMolekulargewicht:165.62N1,N1-Dimethylbiguanide hydrochloride
CAS:Reinheit:95.0%Farbe und Form:SolidMolekulargewicht:165.63000488281251,1-Dimethylbiguanide hydrochloride, 97%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formel:C4H12ClN5Reinheit:97%Farbe und Form:Crystalline powder, WhiteMolekulargewicht:165.63Metformin HCl - Bio-X ™
CAS:Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation. Metformin HCl is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formel:C4H11N5•HClReinheit:Min. 95%Farbe und Form:PowderMolekulargewicht:165.62 g/mol1,1-Dimethylbiguanide hydrochloride
CAS:1,1-Dimethylbiguanide hydrochloride is used as an antidiabetic agent, used in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics, used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formel:C4H12ClN5Farbe und Form:White, Crystalline powderMolekulargewicht:165.63Metformin Hydrochloride
CAS:Formel:C4H11N5·HClReinheit:>98.0%(T)(HPLC)Farbe und Form:White to Almost white powder to crystalMolekulargewicht:165.63Metformin Hydrochloride
CAS:Kontrolliertes ProduktApplications An oral hypoglycemic agent. Slows electron transport in the oxidation pathway in mitochondria. Has been reported to reverse Lupus symptoms in mice in conjunction with 2-deoxy-d-glucose (D239000). Metformin is a well-known type 2 diabetes treatment. Research shows that metformin may inhibit tumor growth both directly and indirectly. Studies indicate that metformin modulates the biology of aging. Metformin blocks the conversion of select substrates into glucose in a redox-dependent manner. References Tucker, G.T., et al.: Brit. J. Clin. Pharmacol., 12, 235 (1981), DeFronzo, R.A., et al.: N. Engl. J. Med., 333, 541 (1995); Chem. and Eng. News, page 7, Feb. 23 (2015); Nir Barzilai et al., Cell Metabolism 23: 1060 June 14 (2016); Chem. and Eng. News, page 7, Feb. 23 (2015); Chem. and Eng. News, page 12, July 30 (2018)Formel:C4H11N5·ClHFarbe und Form:WhiteMolekulargewicht:165.62Metformin hydrochloride
CAS:Metformin hydrochlorideFormel:C4H12N5ClReinheit:100%Farbe und Form:WhiteMolekulargewicht:165.62571,1-Dimethylbiguanide hydrochloride
CAS:1,1-Dimethylbiguanide hydrochlorideFormel:C4H11N5·ClHReinheit:96% (Typical Value in Batch COA)Farbe und Form: white solidMolekulargewicht:165.62g/molMetformin HCl
CAS:Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.Formel:C4H12ClN5Farbe und Form:White PowderMolekulargewicht:165.62 g/molMetformin hydrochloride
CAS:Formel:C4H11N5·HClReinheit:(Titration) 98.0 - 102.0 % (dried basis)Farbe und Form:White or almost white crystalline powderMolekulargewicht:165.62Metformin hydrochloride (mM/ml)
CAS:Formel:C4H12ClN5Reinheit:98%Farbe und Form:SolidMolekulargewicht:165.6246
