CAS: 3682-04-0

Naringenin triacetate is a synthetic derivative of the naturally occurring flavonoid naringenin, which is primarily sourced from citrus fruits. As a derivative, it is characterized by the acetylation of naringenin, which influences its solubility and bioavailability. The primary mode of action involves modulation of various biochemical pathways due to its enhanced lipophilicity, compared to naringenin. This characteristic facilitates its interaction with cellular membranes and intracellular targets. Naringenin triacetate is widely utilized in research settings to explore its potential antioxidant, anti-inflammatory, and anticancer properties. It serves as a vital tool in the study of cellular redox states, inflammation pathways, and the modulation of apoptotic processes. Additionally, its role in influencing metabolic syndrome parameters makes it a compound of interest in metabolic and pharmacokinetic studies. The derivative's structural modification allows researchers to better understand the impact of acetylation on bioactivity and therapeutic potential, thereby offering insights into improved drug formulation and delivery mechanisms.

Naringenin Triacetate is a derivative of the flavonoid Naringenin with good binding affinity for the Nac binding site of the structural domain of the BRD4-BD1.